PT1803820E - A process for the preparation of vitamin k2 - Google Patents

A process for the preparation of vitamin k2 Download PDF

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Publication number
PT1803820E
PT1803820E PT05425932T PT05425932T PT1803820E PT 1803820 E PT1803820 E PT 1803820E PT 05425932 T PT05425932 T PT 05425932T PT 05425932 T PT05425932 T PT 05425932T PT 1803820 E PT1803820 E PT 1803820E
Authority
PT
Portugal
Prior art keywords
vitamin
preparation
dsmz
dsm
december
Prior art date
Application number
PT05425932T
Other languages
Portuguese (pt)
Inventor
Alberto Benedetti
Simona Daly
Roberto Xaiz
Hermes Pagani
Original Assignee
Gnosis Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gnosis Spa filed Critical Gnosis Spa
Publication of PT1803820E publication Critical patent/PT1803820E/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/66—Preparation of oxygen-containing organic compounds containing the quinoid structure
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

A process for the preparation of vitamin K2 (MK - 7) comprising the culture of Bacillus subtilis mutant strain GN13/72 - DSM 17766 deposited on December 05, 2005 at the DSMZ.
PT05425932T 2005-12-29 2005-12-29 A process for the preparation of vitamin k2 PT1803820E (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP05425932A EP1803820B1 (en) 2005-12-29 2005-12-29 A process for the preparation of vitamin K2

Publications (1)

Publication Number Publication Date
PT1803820E true PT1803820E (en) 2009-07-14

Family

ID=36588821

Family Applications (1)

Application Number Title Priority Date Filing Date
PT05425932T PT1803820E (en) 2005-12-29 2005-12-29 A process for the preparation of vitamin k2

Country Status (15)

Country Link
US (1) US7718407B2 (en)
EP (1) EP1803820B1 (en)
JP (1) JP5043425B2 (en)
KR (1) KR101439473B1 (en)
AT (1) ATE434666T1 (en)
CA (1) CA2572373C (en)
CY (1) CY1109266T1 (en)
DE (1) DE602005015133D1 (en)
DK (1) DK1803820T3 (en)
ES (1) ES2326379T3 (en)
HR (1) HRP20090507T1 (en)
PL (1) PL1803820T3 (en)
PT (1) PT1803820E (en)
RS (1) RS51172B (en)
SI (1) SI1803820T1 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0817528D0 (en) * 2008-09-24 2008-10-29 Syntavit As Process
IN2009MU00380A (en) * 2009-02-18 2010-04-02
KR20120016642A (en) * 2009-06-03 2012-02-24 시에이치알. 한센 에이/에스 Bacteria thya(-) mutants with increased vitamin k
DE102010001832A1 (en) 2010-02-11 2011-08-11 Wacker Chemie AG, 81737 Process for the fermentative production of menaquinone-7 with Escherichia coli
KR101196338B1 (en) 2010-06-16 2012-11-01 무주군약초영농조합법인 Bacillus amyloliquefaciens having high productivity of vitamin K2
JP2014150731A (en) * 2013-02-05 2014-08-25 Fuji Oil Co Ltd Food product including menaquinone-7, and method of producing menaquinone-7 with use of microorganism
WO2014131084A1 (en) * 2013-02-27 2014-09-04 The University Of Sydney Fermentation and in situ extraction of menaquinones during microbial culture
JP6411586B2 (en) * 2016-06-15 2018-10-24 アサヒグループホールディングス株式会社 Bone metabolism improver
KR101875502B1 (en) * 2016-08-03 2018-07-09 민병규 Method for producing vitamin K2 from bacillus subtilis using pH-stat fed-batch culture
WO2020123432A1 (en) * 2018-12-11 2020-06-18 The Penn State Research Foundation Method for production of vitamin k using biofilm reactors
CN110499345B (en) * 2019-09-02 2021-05-28 福建康鸿生物科技有限公司 Fermentation method of vitamin k2(MK-7 type)
KR102354881B1 (en) * 2019-10-30 2022-02-07 주식회사 지에프퍼멘텍 Novel Bacillus subtilis natto Isolated from Korean Traditional Soy Bean Paste with High Productivity for High Purity Trans Type Menaquinone-7 and the Use Thereof
US11912654B2 (en) 2021-09-03 2024-02-27 Synergia Life Sciences Pvt. Ltd. Process for stereospecific synthesis of vitamin K2 and its novel intermediates

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4843877B1 (en) * 1970-03-03 1973-12-21
ES2007758A6 (en) * 1987-12-07 1989-07-01 Espanola Petrol A process for the obtention of thermostable alpha-amylases by culturing superproductive microorganisms at high temperatures.
US5024937A (en) * 1989-04-06 1991-06-18 Dow Corning Corporation Method for processing aqueous fermentation broths
JPH069474B2 (en) * 1990-03-20 1994-02-09 有限会社ビセイケン Method for producing alcohol-fermented fermented product and alcohol-fermented fermented food
US5525695A (en) * 1991-10-15 1996-06-11 The Dow Chemical Company Elastic linear interpolymers
JP3272657B2 (en) 1998-01-19 2002-04-08 シャープ株式会社 Switching power supply
JP4068103B2 (en) * 1998-05-17 2008-03-26 洋行 須見 Production method of vitamin K by culture of Yunnan SL-001
US6677143B2 (en) * 1998-05-17 2004-01-13 Honda Trading Company Method for culturing Bacillus subtilis natto to produce water-soluble vitamin K and food product, beverage, or feed containing the cultured microorganism or the vitamin K derivative
JP4104741B2 (en) * 1998-09-08 2008-06-18 旭松食品株式会社 Vitamin K high-producing strain and method for producing vitamin K using the same
JP4264159B2 (en) * 1999-04-07 2009-05-13 株式会社ミツカングループ本社 Vitamin K2 high productivity natto, its breeding method and natto
JP2001346546A (en) * 2000-06-08 2001-12-18 Kikkoman Corp Method for producing vitamin k concentrate
JP2002034554A (en) * 2000-07-28 2002-02-05 Mitsukan Group Honsha:Kk Bacillus natto producing vitamin k at high concentration, method for breeding the same and fermented soybean
JP2005237300A (en) * 2004-02-26 2005-09-08 Aichi Prefecture Food material and method for producing the same

Also Published As

Publication number Publication date
CY1109266T1 (en) 2014-07-02
DE602005015133D1 (en) 2009-08-06
KR20070072383A (en) 2007-07-04
JP2007181461A (en) 2007-07-19
DK1803820T3 (en) 2009-10-12
PL1803820T3 (en) 2009-12-31
EP1803820A1 (en) 2007-07-04
CA2572373C (en) 2014-02-04
CA2572373A1 (en) 2007-06-29
EP1803820B1 (en) 2009-06-24
ATE434666T1 (en) 2009-07-15
US20070154998A1 (en) 2007-07-05
ES2326379T3 (en) 2009-10-08
JP5043425B2 (en) 2012-10-10
RS51172B (en) 2010-10-31
KR101439473B1 (en) 2014-09-11
HRP20090507T1 (en) 2009-10-31
SI1803820T1 (en) 2009-10-31
US7718407B2 (en) 2010-05-18

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