PT1386608E - Remedial agent for glomerular disease - Google Patents

Remedial agent for glomerular disease Download PDF

Info

Publication number
PT1386608E
PT1386608E PT02720493T PT02720493T PT1386608E PT 1386608 E PT1386608 E PT 1386608E PT 02720493 T PT02720493 T PT 02720493T PT 02720493 T PT02720493 T PT 02720493T PT 1386608 E PT1386608 E PT 1386608E
Authority
PT
Portugal
Prior art keywords
glomerular
glomerular disease
remedial agent
preventive
therapeutic agent
Prior art date
Application number
PT02720493T
Other languages
Portuguese (pt)
Inventor
Takashi Nakagawa
Makoto Suda
Yoichi Yamauchi
Original Assignee
Kowa Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kowa Co filed Critical Kowa Co
Publication of PT1386608E publication Critical patent/PT1386608E/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D215/14Radicals substituted by oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The present invention is directed to a preventive or therapeutic agent for a glomerular disease comprising as an active ingredient a compound represented by formula (1): <CHEM> or a salt thereof. The preventive or therapeutic agent for glomerular diseases is useful for preventing or treating a variety of glomerular diseases including chronic glomerular nephritis.
PT02720493T 2001-04-19 2002-04-18 Remedial agent for glomerular disease PT1386608E (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2001121058 2001-04-19
JP2001361257 2001-11-27
PCT/JP2002/003870 WO2002085363A1 (en) 2001-04-19 2002-04-18 Remedial agent for glomerular disease

Publications (1)

Publication Number Publication Date
PT1386608E true PT1386608E (en) 2011-07-26

Family

ID=26613829

Family Applications (1)

Application Number Title Priority Date Filing Date
PT02720493T PT1386608E (en) 2001-04-19 2002-04-18 Remedial agent for glomerular disease

Country Status (6)

Country Link
US (1) US7504415B2 (en)
EP (1) EP1386608B1 (en)
JP (1) JP4235000B2 (en)
AT (1) ATE511395T1 (en)
PT (1) PT1386608E (en)
WO (1) WO2002085363A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE511395T1 (en) 2001-04-19 2011-06-15 Kowa Co AGENTS FOR THE TREATMENT OF GLOMERULOPATHY
MY131170A (en) * 2002-03-28 2007-07-31 Nissan Chemical Ind Ltd Therapeutic agent for glomerular disease
WO2006046528A1 (en) 2004-10-29 2006-05-04 Kowa Co., Ltd. Therapeutic agent for glomerular disease
WO2008082537A2 (en) 2006-12-19 2008-07-10 The General Hospital Corporation Compounds for modulating integrin cd11b/cd18
ES2766751T3 (en) 2012-04-20 2020-06-15 Gb006 Inc Compositions for the regulation of integrins

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2569746B2 (en) 1987-08-20 1997-01-08 日産化学工業株式会社 Quinoline mevalonolactones
CA1336714C (en) * 1987-08-20 1995-08-15 Yoshihiro Fujikawa Quinoline type mevalonolactone inhibitors of cholesterol biosynthesis
CA2052014A1 (en) * 1990-10-19 1992-04-20 Henry Y. Pan Method for preventing diabetic complications employing a cholesterol lowering drug alone or in combination with an ace inhibitor
JPH08198898A (en) * 1995-01-30 1996-08-06 Takeda Chem Ind Ltd Cholesterol-taking out accelerator
US6090839A (en) * 1996-12-23 2000-07-18 Merck & Co., Inc. Antidiabetic agents
US6147109A (en) 1997-10-14 2000-11-14 The General Hospital Corporation Upregulation of Type III endothelial cell Nitric Oxide Synthase by HMG-CoA reductase inhibitors
CA2405793A1 (en) 2000-04-12 2001-10-18 Novartis Ag Combination of organic compounds
US6620821B2 (en) * 2000-06-15 2003-09-16 Bristol-Myers Squibb Company HMG-CoA reductase inhibitors and method
AU2001284413A1 (en) * 2000-08-30 2002-03-13 Sankyo Company Limited Medicinal compositions for preventing or treating heart failure
PL361097A1 (en) * 2000-10-12 2004-09-20 Nissan Chemical Industries, Ltd. Preventives and remedies for complications of diabetes
ATE511395T1 (en) 2001-04-19 2011-06-15 Kowa Co AGENTS FOR THE TREATMENT OF GLOMERULOPATHY

Also Published As

Publication number Publication date
JPWO2002085363A1 (en) 2004-08-05
WO2002085363A1 (en) 2002-10-31
EP1386608A4 (en) 2005-02-09
EP1386608A1 (en) 2004-02-04
EP1386608B1 (en) 2011-06-01
ATE511395T1 (en) 2011-06-15
US20040116468A1 (en) 2004-06-17
JP4235000B2 (en) 2009-03-04
US7504415B2 (en) 2009-03-17

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