PT1309575E - BIPHENYL DERIVATIVES AND THEIR USE AS ACTIVATORS OF THE PPAR RANGE RECEIVERS - Google Patents
BIPHENYL DERIVATIVES AND THEIR USE AS ACTIVATORS OF THE PPAR RANGE RECEIVERSInfo
- Publication number
- PT1309575E PT1309575E PT01965314T PT01965314T PT1309575E PT 1309575 E PT1309575 E PT 1309575E PT 01965314 T PT01965314 T PT 01965314T PT 01965314 T PT01965314 T PT 01965314T PT 1309575 E PT1309575 E PT 1309575E
- Authority
- PT
- Portugal
- Prior art keywords
- activators
- biphenyl derivatives
- range receivers
- ppar
- ppar range
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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- A61P17/06—Antipsoriatics
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- A—HUMAN NECESSITIES
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
- C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/47—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
- C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/51—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to an acyclic carbon atom of a carbon skeleton containing six-membered aromatic rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
- C07C233/81—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
- C07C233/82—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/87—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom of a carbon skeleton containing six-membered aromatic rings
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- C—CHEMISTRY; METALLURGY
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
- C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/36—Oxygen or sulfur atoms
- C07D207/40—2,5-Pyrrolidine-diones
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/22—Nitrogen and oxygen atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/34—Oxygen atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/70—Biological properties of the composition as a whole
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0010447A FR2812876B1 (en) | 2000-08-08 | 2000-08-08 | NOVEL BIAROMATIC COMPOUNDS THAT ACTIVATE PPAR-GAMMA TYPE RECEPTORS AND THEIR USE IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS |
Publications (1)
Publication Number | Publication Date |
---|---|
PT1309575E true PT1309575E (en) | 2005-10-31 |
Family
ID=8853412
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT01965314T PT1309575E (en) | 2000-08-08 | 2001-08-03 | BIPHENYL DERIVATIVES AND THEIR USE AS ACTIVATORS OF THE PPAR RANGE RECEIVERS |
Country Status (20)
Country | Link |
---|---|
US (1) | US6927228B2 (en) |
EP (1) | EP1309575B1 (en) |
JP (1) | JP2004505958A (en) |
KR (1) | KR20030051611A (en) |
CN (1) | CN1468226A (en) |
AR (1) | AR032888A1 (en) |
AT (1) | ATE297386T1 (en) |
AU (2) | AU2001285981B2 (en) |
BR (1) | BR0113251A (en) |
CA (1) | CA2418895A1 (en) |
DE (1) | DE60111393T2 (en) |
DK (1) | DK1309575T3 (en) |
ES (1) | ES2245373T3 (en) |
FR (1) | FR2812876B1 (en) |
MX (1) | MXPA03001184A (en) |
PL (1) | PL360292A1 (en) |
PT (1) | PT1309575E (en) |
RU (1) | RU2280033C2 (en) |
WO (1) | WO2002012210A1 (en) |
ZA (1) | ZA200300667B (en) |
Families Citing this family (61)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1214305A1 (en) | 1999-08-31 | 2002-06-19 | Maxia Pharmaceuticals, Inc. | Benzylidene-thiazolidinediones and analogues and their use in the treatment of inflammation |
JP2005506290A (en) * | 2001-03-07 | 2005-03-03 | マキシア・ファーマシューティカルズ・インコーポレイテッド | Heterocyclic derivatives for treating cancer and other proliferative diseases |
WO2002072543A2 (en) | 2001-03-08 | 2002-09-19 | Maxia Pharmaceuticals, Inc. | Rxr activating molecules |
TWI311133B (en) | 2001-04-20 | 2009-06-21 | Eisai R&D Man Co Ltd | Carboxylic acid derivativeand the salt thereof |
US20040152746A1 (en) * | 2001-04-30 | 2004-08-05 | Bardsley Hazel Judith | Treatment of scarring and related conditions using ppar-gamma activators |
EP1394147A4 (en) * | 2001-06-04 | 2007-10-24 | Eisai R&D Man Co Ltd | Carboxylic acid derivative and medicine comprising salt or ester of the same |
JP2005500379A (en) * | 2001-08-17 | 2005-01-06 | インサイト サンディエゴ インコーポレーテッド | Oxime derivatives to treat dyslipidemia and hypercholesterolemia |
JP2005513026A (en) | 2001-11-15 | 2005-05-12 | インサイト サン ディエゴ インコーポレイテッド | Hypercholesterolemia, dyslipidemia and other metabolic disorders; N-substituted heterocycles to treat cancer and other diseases |
JP2005518376A (en) | 2001-12-14 | 2005-06-23 | ノボ ノルディスク アクティーゼルスカブ | Compounds and their use to reduce the activity of hormone sensitive lipases |
US6908939B2 (en) | 2001-12-21 | 2005-06-21 | Galderma Research & Development S.N.C. | Biaromatic ligand activators of PPARγ receptors |
FR2833949B1 (en) * | 2001-12-21 | 2005-08-05 | Galderma Res & Dev | NOVEL PPARy RECEPTOR ACTIVATION LIGANDS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN HUMAN MEDICINE AND COSMETICS |
FR2836683B1 (en) * | 2002-03-01 | 2006-06-23 | Galderma Res & Dev | NOVEL PPARy RECEPTOR ACTIVATION LIGANDS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN HUMAN MEDICINE AND COSMETICS |
US7196108B2 (en) | 2002-03-08 | 2007-03-27 | Incyte San Diego Inc. | Bicyclic heterocycles for the treatment of diabetes and other diseases |
US7102000B2 (en) * | 2002-03-08 | 2006-09-05 | Incyte San Diego Inc. | Heterocyclic amide derivatives for the treatment of diabetes and other diseases |
JP4515911B2 (en) | 2002-10-07 | 2010-08-04 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | Modulation of anxiety by blocking anandamide hydrolysis |
PL374758A1 (en) * | 2002-10-24 | 2005-10-31 | Merck Patent Gmbh | Methylene urea derivatives |
RU2005119167A (en) | 2002-11-19 | 2006-01-20 | Галдерма Ресерч Энд Девелопмент, С.Н.С. (Fr) | NEW BIARY AROMATIC COMPOUNDS ACTIVATORS OF TYPE PPARY AND THEIR APPLICATION IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS |
FR2847251B1 (en) * | 2002-11-19 | 2006-11-17 | NOVEL BI-AROMATIC ACTIVATED PPARy RECEPTOR-ACTIVE COMPOUNDS AND THEIR USE IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | |
BR0315951A (en) * | 2002-11-25 | 2005-09-13 | Galderma Res & Dev | Compounds, cosmetic composition, cosmetic use of a composition, use of a compound and pharmaceutical composition |
FR2847580B1 (en) * | 2002-11-25 | 2006-03-03 | Galderma Res & Dev | NOVEL BI-AROMATIC RECEPTOR-ACTIVATING COMPOUNDS OF PPARy TYPE AND THEIR USE IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS |
FR2848553B1 (en) * | 2002-12-12 | 2007-03-30 | Galderma Res & Dev | NOVEL MODULATING COMPOUNDS OF PPARY RECEPTORS AND THEIR USE IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS |
CA2506732A1 (en) | 2002-12-12 | 2004-06-24 | Galderma Research & Development, S.N.C. | Compounds which modulate ppar.gamma. type receptors, and use thereof in cosmetic or pharmaceutical compositions |
US20050014767A1 (en) * | 2003-01-29 | 2005-01-20 | Magnus Pfahl | Benzoxazole, benzothiazole, and benzimidazole derivatives for the treatment of cancer and other diseases |
US20050038098A1 (en) * | 2003-04-18 | 2005-02-17 | Catherine Tachdjian | Substituted dihydronaphthalene and isochroman compounds for the treatment of metabolic disorders, cancer and other diseases |
EP1638964B1 (en) * | 2003-06-20 | 2011-07-27 | Galderma Research & Development | Novel compounds that modulate ppar-gamma type receptors, and use thereof in cosmetic or pharmaceutical compositions |
FR2856401B1 (en) * | 2003-06-20 | 2010-02-12 | Galderma Res & Dev | NOVEL MODULATING COMPOUNDS OF PPARGAMMA RECEPTORS AND THEIR USE IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS |
MXPA06012679A (en) * | 2004-05-06 | 2007-01-16 | Galderma Res & Dev | NOVEL BIAROMATIC COMPOUNDS WHICH ACTIVATE PPARgamma-TYPE RECEPTORS, THEIR PROCESS OF PREPARATION AND THEIR USE IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS. |
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AU3275999A (en) * | 1998-03-10 | 1999-09-27 | Ono Pharmaceutical Co. Ltd. | Carboxylic acid derivatives and drugs containing the same as the active ingredient |
WO2003018011A1 (en) * | 2001-08-24 | 2003-03-06 | Wyeth Holdings Corporation | 5-(substituted)-5-(substitutedsulfonyl or sulfanyl)thiazolidine-2,4-diones useful for inhibition of farnesyl-protein transferase |
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2000
- 2000-08-08 FR FR0010447A patent/FR2812876B1/en not_active Expired - Fee Related
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2001
- 2001-08-03 JP JP2002518187A patent/JP2004505958A/en not_active Withdrawn
- 2001-08-03 CA CA002418895A patent/CA2418895A1/en not_active Abandoned
- 2001-08-03 ES ES01965314T patent/ES2245373T3/en not_active Expired - Lifetime
- 2001-08-03 MX MXPA03001184A patent/MXPA03001184A/en active IP Right Grant
- 2001-08-03 EP EP01965314A patent/EP1309575B1/en not_active Expired - Lifetime
- 2001-08-03 AU AU2001285981A patent/AU2001285981B2/en not_active Ceased
- 2001-08-03 DE DE60111393T patent/DE60111393T2/en not_active Expired - Lifetime
- 2001-08-03 RU RU2003106424/04A patent/RU2280033C2/en not_active IP Right Cessation
- 2001-08-03 DK DK01965314T patent/DK1309575T3/en active
- 2001-08-03 AU AU8598101A patent/AU8598101A/en active Pending
- 2001-08-03 CN CNA018170080A patent/CN1468226A/en active Pending
- 2001-08-03 BR BR0113251-2A patent/BR0113251A/en not_active IP Right Cessation
- 2001-08-03 AT AT01965314T patent/ATE297386T1/en not_active IP Right Cessation
- 2001-08-03 KR KR10-2003-7001815A patent/KR20030051611A/en not_active Application Discontinuation
- 2001-08-03 WO PCT/FR2001/002543 patent/WO2002012210A1/en active IP Right Grant
- 2001-08-03 PL PL01360292A patent/PL360292A1/en not_active Application Discontinuation
- 2001-08-03 PT PT01965314T patent/PT1309575E/en unknown
- 2001-08-06 AR ARP010103748A patent/AR032888A1/en unknown
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2003
- 2003-01-24 ZA ZA200300667A patent/ZA200300667B/en unknown
- 2003-02-10 US US10/360,615 patent/US6927228B2/en not_active Expired - Fee Related
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BR0113251A (en) | 2003-06-24 |
CN1468226A (en) | 2004-01-14 |
FR2812876A1 (en) | 2002-02-15 |
WO2002012210A9 (en) | 2002-04-18 |
EP1309575B1 (en) | 2005-06-08 |
PL360292A1 (en) | 2004-09-06 |
RU2280033C2 (en) | 2006-07-20 |
DE60111393T2 (en) | 2006-03-23 |
AU2001285981B2 (en) | 2006-01-19 |
US20040039038A1 (en) | 2004-02-26 |
MXPA03001184A (en) | 2003-10-15 |
AR032888A1 (en) | 2003-12-03 |
DE60111393D1 (en) | 2005-07-14 |
ES2245373T3 (en) | 2006-01-01 |
ATE297386T1 (en) | 2005-06-15 |
WO2002012210A1 (en) | 2002-02-14 |
DK1309575T3 (en) | 2005-09-12 |
US6927228B2 (en) | 2005-08-09 |
JP2004505958A (en) | 2004-02-26 |
AU8598101A (en) | 2002-02-18 |
EP1309575A1 (en) | 2003-05-14 |
ZA200300667B (en) | 2004-02-11 |
KR20030051611A (en) | 2003-06-25 |
FR2812876B1 (en) | 2002-09-27 |
CA2418895A1 (en) | 2002-02-14 |
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