PT1237838E - NEW PROCESS - Google Patents

NEW PROCESS

Info

Publication number
PT1237838E
PT1237838E PT00983617T PT00983617T PT1237838E PT 1237838 E PT1237838 E PT 1237838E PT 00983617 T PT00983617 T PT 00983617T PT 00983617 T PT00983617 T PT 00983617T PT 1237838 E PT1237838 E PT 1237838E
Authority
PT
Portugal
Prior art keywords
useful
preparation
new process
present
enantioner
Prior art date
Application number
PT00983617T
Other languages
Portuguese (pt)
Inventor
Kjell Andersson
Alan Eric Fischer
Panagiotis Ioannidis
Magnus Larsson
Maria Larsson
Sivaprasad Sivadasan
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of PT1237838E publication Critical patent/PT1237838E/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/734—Ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/377—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/41—Preparation of salts of carboxylic acids
    • C07C51/412—Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Separation By Low-Temperature Treatments (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)

Abstract

The present invention relates to novel resolution methods, which are useful in the preparation of enantiomerically enriched intermediates which in their turn are useful in the prepartion of compounds with a pharmacological effect on the insulin resistance syndrome (IRS). It is such a process that the present inventions sets out to define, and more particularly for the preparation of the (S)-enantioner of certain 2-ethoxy-3-(4-hydroxyphenyl)propanoic acids and derivatives thereof.
PT00983617T 1999-12-03 2000-11-29 NEW PROCESS PT1237838E (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9904415A SE9904415D0 (en) 1999-12-03 1999-12-03 New process

Publications (1)

Publication Number Publication Date
PT1237838E true PT1237838E (en) 2004-08-31

Family

ID=20417980

Family Applications (1)

Application Number Title Priority Date Filing Date
PT00983617T PT1237838E (en) 1999-12-03 2000-11-29 NEW PROCESS

Country Status (20)

Country Link
US (2) US7002037B2 (en)
EP (1) EP1237838B1 (en)
JP (1) JP2003515578A (en)
KR (1) KR100794091B1 (en)
CN (1) CN1213016C (en)
AT (1) ATE264287T1 (en)
AU (1) AU765938B2 (en)
BR (1) BR0016136A (en)
CA (1) CA2392032C (en)
DE (1) DE60009953T2 (en)
DK (1) DK1237838T3 (en)
ES (1) ES2218258T3 (en)
IL (2) IL149576A0 (en)
MX (1) MXPA02005321A (en)
NO (1) NO20022604L (en)
PT (1) PT1237838E (en)
SE (1) SE9904415D0 (en)
TR (1) TR200401717T4 (en)
WO (1) WO2001040159A1 (en)
ZA (1) ZA200203705B (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9812770A (en) 1997-10-27 2000-12-12 Reddy Research Foundation Bicyclic compounds, process for their preparation and pharmaceutical compositions containing the same
CN1280574A (en) 1997-10-27 2001-01-17 雷迪研究基金会 New heterocyclic compounds and their use in medicine, process for their prepartion and pharmaceutical compositions containing them
US6369067B1 (en) 1997-10-27 2002-04-09 Dr. Reddy's Research Foundation Monocyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them
KR100517644B1 (en) 1997-10-27 2005-09-28 닥터 레디스 레보러터리즈 리미티드 Novel tricyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them
US6440961B1 (en) 1997-10-27 2002-08-27 Dr. Reddy's Research Foundation Tricyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them
US6531596B1 (en) 1998-10-29 2003-03-11 Dr. Reddy's Laboratories Ltd. Process for the preparation of new antidiabetic agents
WO2000026200A1 (en) 1998-10-29 2000-05-11 Dr. Reddy's Research Foundation An improved process for the preparation of new antidiabetic agents
SE9904415D0 (en) * 1999-12-03 1999-12-03 Astra Ab New process
US6897199B2 (en) 2001-02-05 2005-05-24 Dr. Reddy's Laboratories Ltd. Pharmaceutically acceptable salts of phenoxazine and phenothiazine compounds
US6962940B2 (en) 2002-03-20 2005-11-08 Celgene Corporation (+)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione: methods of using and compositions thereof
US20070142472A1 (en) * 2003-11-27 2007-06-21 Tohru Yokozawa Process for producing optically active 3-(4-hydroxyphenyl)proprionic acids
DE102004035034A1 (en) 2004-07-20 2006-02-16 Degussa Ag Resolution of p-hydroxyphenyl-2-alkoxy-propionic acids
ITMI20061297A1 (en) 2006-07-04 2008-01-05 Laboratorio Chimico Int Spa PROCEDURE FOR THE PREPARATION OF ACID (R) - (-) - 3- (CARBAMYLMETHYL) -5-METHYLESANOIC AND PREGABALIN AND INTERMEDIATE OF SYNTHESIS
KR101558005B1 (en) 2007-03-08 2015-10-06 알비레오 에이비 2--3- 2-substituted-3-phenylpropionic acid derivatives and their use in the treatment of inflammatory bowel disease
CN102131766B (en) * 2008-08-25 2013-12-11 杜邦电子聚合物公司 New propanoates and processes for preparing the same
CN101838195B (en) * 2009-03-17 2014-08-13 天士力制药集团股份有限公司 Chemical resolution preparation method for optical pure Beta-3, 4-dyhydroxyophenyl lactic acid
CN104447294A (en) * 2014-11-24 2015-03-25 苏州乔纳森新材料科技有限公司 Chiral resolution method of 3-cyclohexene-1-formic acid

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5306725A (en) 1989-03-01 1994-04-26 Katayama Chemical Inc. Stabilized isothiazolone liquid formulation
NZ253742A (en) 1992-07-03 1997-06-24 Smithkline Beecham Plc Heterocyclylaminoalkoxy substituted phenyl derivatives and pharmaceutical compositions
US5232945A (en) 1992-07-20 1993-08-03 Pfizer Inc. 3-aryl-2-hydroxypropionic acid derivatives and analogs as antihypertensives
GB9604242D0 (en) * 1996-02-28 1996-05-01 Glaxo Wellcome Inc Chemical compounds
KR100517644B1 (en) 1997-10-27 2005-09-28 닥터 레디스 레보러터리즈 리미티드 Novel tricyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them
SE9801992D0 (en) 1998-06-04 1998-06-04 Astra Ab New 3-aryl-2-hydroxypropionic acid derivative I
MA26634A1 (en) 1998-06-04 2004-12-20 Astra Ab NOVEL 3-ARYL PROPIONIC ACID DERIVATIVES AND THE LIKE
SE9801990D0 (en) * 1998-06-04 1998-06-04 Astra Ab New 3-aryl propionic acid derivatives and analogs
SE9904415D0 (en) * 1999-12-03 1999-12-03 Astra Ab New process

Also Published As

Publication number Publication date
WO2001040159A1 (en) 2001-06-07
DE60009953T2 (en) 2005-03-31
CA2392032A1 (en) 2001-06-07
TR200401717T4 (en) 2004-09-21
US20060069283A1 (en) 2006-03-30
ES2218258T3 (en) 2004-11-16
KR100794091B1 (en) 2008-01-10
SE9904415D0 (en) 1999-12-03
IL149576A (en) 2007-09-20
DE60009953D1 (en) 2004-05-19
ATE264287T1 (en) 2004-04-15
EP1237838B1 (en) 2004-04-14
CN1433393A (en) 2003-07-30
NO20022604L (en) 2002-07-11
EP1237838A1 (en) 2002-09-11
BR0016136A (en) 2002-08-20
JP2003515578A (en) 2003-05-07
CA2392032C (en) 2008-10-28
US7002037B2 (en) 2006-02-21
ZA200203705B (en) 2003-10-29
DK1237838T3 (en) 2004-07-12
IL149576A0 (en) 2002-11-10
MXPA02005321A (en) 2002-12-06
KR20020058071A (en) 2002-07-12
US20030139474A1 (en) 2003-07-24
AU765938B2 (en) 2003-10-02
NO20022604D0 (en) 2002-05-31
CN1213016C (en) 2005-08-03
AU2034901A (en) 2001-06-12

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