PT108561B - HERBICIDE MIXTURE - Google Patents

Abstract

The present invention provides a synergistic herbicidal composition comprising a mixture of methyl isodiphosphorus (Compound I) or its salts, fluorosulfame (Compound II) or its salts and diflulufenium. The present invention also relates to a process for controlling infestation of winter and spring cranberry crops by the application of said composition.

Description

DESCRIPTION '' HERBICIDE MIXTURE

AREA OF THE INVENTION

This invention falls within the field of crop protection and relates specifically to a synergistic herbicidal combination comprising iodosulfuron-methyl or its salts, florasulam or its salts and diflufenication, and the preparation and use of said composition for the control of weeds of winter and spring cereal crops.

BACKGROUND

THE INVENTION

In the field of crop protection, the use of an active substance to control weeds can become increasingly difficult over time, resulting from the emergence of resistance to the herbicides used. This leads to loss of efficiency in the control of weeds and, consequently, loss of crop production and crop yield.

A very developed way of approaching this problem

consists of use of a combination of many different substances active presenting many different mechanisms biochemists of here.

the combination of a plurality of active ingredients frequently causes problems of physical or basic incompatibility, which can be demonstrated, for example, in the lack of physical stability of the formulation, degradation of one or more active substances over the time, antagonism in terms of biological efficiency or phytotoxicity effects in the culture.

compound (I), iodosulfuron-methyl (IUPAC: 4-iodo-2- [3 (4-methoxy-6-methyl-1,3,5-triazin-2-yl) ureidosulfonyl] methyl benzoate), whose structural formula and:

and a description of the herb 丄 cid

EP 0574418 ・ in European Patent

Preferably the sodium salt of iodosulfuron-methyl (iodosulfuron-methyl-sodium) _r which has the structural formula (la):

Iodosulfuron-methane is a sulfon that acts by inhibiting the biosynthesis of essential amino acids from susceptible plants, through the inhibition of the enzyme acetolactate synthase (ALS) ・

It is known to be used in the initial post-emergence (both in terms of crops and weeds) in wheat. The weeds controlled are ryegrass (Lolium rigidium) _r Balance (Avena spp), annual Phalaris (Phalaris paradoxa) , and several broadleaf weeds.

compound (II), florasulam (IUPAC: 2 ^r r 6 ^r r 8-trifluoro-5metoxifl ^^ Jtriazolofl ^ Sc] pyrimidin-2-sulfonanilide), described in European Patent EP 0343752, has the following structural formula:

florasulame is a mid azolopan sulfonan used in post-emergence on cereals to control broadleaf weeds, which acts by inhibiting acetolactate synthase (ALS).

compound (III), diflufenicao, (IUPAC: 2 ^r _r 4 ^r -difluoro-2 (a, a, a-trifluoro - ^? - tolyloxy) nicotinanilide), described in European Patent EP 053011, has the following structural formula:

F (III) diflufenication is a pyridine-carboxamide that can be used in pre- or post-emergence in cereals to control broadleaf weeds and which acts by inhibiting phytoenodeshydrogenase, a key enzyme in the biosynthesis of carotenoids, pigments that are responsible for absorbing light for photosynthesis.

There are patent documents that refer to the use of the above mentioned active ingredients in the composition of herbicidal mixtures:

European Patent EP 0831707 Bl refers to combinations of the 4-iodo-2 - [(4-methoxy-6-methyl-1,2,5-triazin-2yl) carbamoylsulfamoyl] esters, in particular iodosulfuromethyl and benzoic acid of its salts, with another active substance selected from a set that includes diflufenicao. The patent presents an example of synergy in combating Lolium multiflorum, in which the addition of 13 g / ha of diflufenication (which up to a dose of 25 g / ha did not reveal any herbicidal activity) to 10 g / ha of methyl iodosulfuron allowed to obtain an increase in efficiency in the control of said weed of patent application EP2095712 A1 refers to combinations of diflufenicao with florasulam. The patent application presents an example of synergy in combating Lolium mul tiflorum, in which neither the use of 9 g / ha of diflufenica nor the use of 0.5 g / ha of florasulam showed any herbicidal activity, but the combination of 9 g / ha of diflufenicao with 0.5 g / ha of florasulam allowed to obtain an efficiency of 30

6 _Z 3

In one aspect of the invention, the process is characterized in that 7.5 g / ha is applied to 10 g / ha of iodosulfurization; 3 g / ha to 4 g / ha of florasulam and 60 g / ha to 80 g / ha of diflufenicao.

DETAILED DESCRIPTION OF THE INVENTION The aim of the present invention is to provide a mixture of herbicidal active substances showing high efficiency in the control of weeds in winter and spring cereal crops (hard and soft wheat, barley, triticale oats and rye) selected from the group comprising Anagallis arvensis _f Anthemis spp. _r Galium aparine _f Lolium multiflorum ^ Lolium rigidum _f Matricaria chamomilla _f Papaver rhoeas _f Pieris echioides _f Poa annua _f Rumex crispus _f Sinapis arvensis _f Stellaria media and Veronica spp.

It was surprisingly found that combining iodosulfuron-methyl (compound I) or its sodium salt (compound la) with florasulam (compound II) and diflufenication (compound III), there is a synergistic effect on biological efficiency, which translates into an unexpected increase in efficiency when compared to the effectiveness of each of the active ingredients ・

It is synergistic in effect to allow lower application doses or a more potent herbicidal action with the same application doses, which translates into an economically more advantageous process for the user and also more favorable from an ecological point of view.

All concentrations of the active substances referred to in the present application are expressed as mass percentage (

The formulation can be presented in the form of wettable powder (WP), water-dispersible granules (WG), aqueous suspension (SC), or oil suspension (OD).

The formulations are prepared in a known manner, for example, by mixing the active compounds with other formulants selected from dispersants, wetters, disintegrants, stabilizers, pH and viscosity correctors, inert and combinations thereof.

Examples of preferred dispersants are sodium or calcium lignosulfonates (Borresperse pH (for example citric acid) and inert (for example, silica or kaolin).

The application rates of the mixture according to the invention are in the range of 7.5 g / ha to 10 g / ha of iodosulfurization; 3 g / ha to 4 g / ha of florasulam and 60 g / ha to 80 g / ha of diflufenicao.

Example of formu 丄 且

By way of example, a formulation in the form of water-dispersible granules (WG) is carried out using the following composition and procedure:

Component

Compounds Ia _z II and III and cloquintocet-mexyl are mixed and subsequently ground in an air jet mill, until a sufficiently fine particle size (at least 95

Synergic effect

To quantify the synergistic effect resulting from the association of active substances, the methodology described by Colby (Colby, SR, '' Calculating synergistic and antagonistic response of herbicide compositions ^, Weeds 15, pp 20-22, 1967) was used, according to which the expected efficiency (EE) for the mixture of active ingredients is compared using the Colby formula:

EE = x + y - (xy) / 100 where:

-EE and the expected efficiency, in%, using the mixture of active compounds

B in concentrations a and b.

-x and efficiency, in%, using the active compound in concentration a;

-yea efficiency, in%, using the active compound in concentration b;

with the efficiency observed experimentally.

For a mixture of three active substances A, the above referendum presents a modification of the

Colby according to which the expected efficiency (EE) is determined by:

(xy + xz + yz) / 100 + (xyz) / 10000 where:

-x and y are defined as in the previous formula;

-z and the efficiency, in%, using the active compound C in concentration c.

-EE and the expected efficiency, in

TABLE A

Efficiency in controlling inf controlostant㊀ Galium aparine after 28 days

Active substance Dose of Efficacy (active substance applied, g / h synergistic effect that translates into an increased efficiency in combating weeds in winter and spring crops.

Claims (4)

REIVINDl ： CACHES 1. Synergistic herbicidal composition characterized by comprising a set of active substances consisting of iodosulfuron-methyl or its salts, florasulam or its salts and diflufenication. 2. Herbicidal composition according to claim 1, characterized by: 一the range of iodosulfuron concentraQao is between 4,0 hard wheat and soft _z barley, triticale, oats and rye, selected from the group comprising _F Anagallis arvensis Anthemis spp. _r Galium aparine _f Lolium multiflorum ^ Lolium rigidum _f Matricaria chamomilla _f Papaver rhoeas _f Pieris echioides _f Poa annua _r Rumex crlspus _f Sinapis arvensis _f Stellaria media e Veronica spp · 7. Process for combating weeds of hard and common wheat, barley, triticale, oats and rye, characterized in that a herbicidal composition according to any one of claims 1 to 5 is applied to these or to the soil. Process according to claim 7, characterized in that 7.5 g / ha is applied to 10 g / ha of iodosulfurization; 3 g / ha to 4 g / ha of florasulam and 60 g / ha to 80 g / ha of diflufenicao.