PT1056542E - PARALLEL TRANSPORT MANDRIS USING REPULSIVE FIELD ORIENTATION - Google Patents
PARALLEL TRANSPORT MANDRIS USING REPULSIVE FIELD ORIENTATIONInfo
- Publication number
- PT1056542E PT1056542E PT99908261T PT99908261T PT1056542E PT 1056542 E PT1056542 E PT 1056542E PT 99908261 T PT99908261 T PT 99908261T PT 99908261 T PT99908261 T PT 99908261T PT 1056542 E PT1056542 E PT 1056542E
- Authority
- PT
- Portugal
- Prior art keywords
- bead
- beads
- repulsive
- control
- collection zones
- Prior art date
Links
- 239000011324 bead Substances 0.000 abstract 20
- 239000004020 conductor Substances 0.000 abstract 2
- 239000003989 dielectric material Substances 0.000 abstract 1
- 238000007599 discharging Methods 0.000 abstract 1
- 230000005684 electric field Effects 0.000 abstract 1
- 230000014759 maintenance of location Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L13/00—Cleaning or rinsing apparatus
- B01L13/02—Cleaning or rinsing apparatus for receptacle or instruments
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00457—Dispensing or evacuation of the solid phase support
- B01J2219/00459—Beads
- B01J2219/00468—Beads by manipulation of individual beads
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/02—Adapting objects or devices to another
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00178—Special arrangements of analysers
- G01N2035/00237—Handling microquantities of analyte, e.g. microvalves, capillary networks
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T279/00—Chucks or sockets
- Y10T279/23—Chucks or sockets with magnetic or electrostatic means
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Clinical Laboratory Science (AREA)
- Container, Conveyance, Adherence, Positioning, Of Wafer (AREA)
- Sampling And Sample Adjustment (AREA)
- Specific Conveyance Elements (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Load-Engaging Elements For Cranes (AREA)
- Control And Safety Of Cranes (AREA)
- Steering Control In Accordance With Driving Conditions (AREA)
- Escalators And Moving Walkways (AREA)
- Motorcycle And Bicycle Frame (AREA)
- Electrostatic Spraying Apparatus (AREA)
- Electrostatic Separation (AREA)
- Adornments (AREA)
Abstract
Bead transporter chucks for selective pick up and discharging of polymer beads for chemical synthesis or analysis, whereby repulsive field conductors are arranged around bead electrodes used for selectively attracting and retaining beads. Problems of bead control are addressed by adding repulsive fields to help guide and direct beads to desired or designated bead collection zones. The repulsive electrodes create non-uniform electric fields that control, focus, and deflect charged beads in the vicinity of the bead collection zone, helping prevent multiple bead retention at intended bead collection zones. For better bead control, and allowing manipulation of beads with higher charge/mass ratios, dielectric material may be positioned around the bead electrode and between the bead electrode and the repulsive field conductor. Multiple bead electrodes may be provided to form two or more bead collection zones, and these may selectively addressed and controlled (e.g, x-y addressing) for individual and selective control of the bead collection zones. Methods and applied voltages are given for using the bead transporter chuck to transport and dispense beads.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/026,303 US6096368A (en) | 1998-02-19 | 1998-02-19 | Bead transporter chucks using repulsive field guidance and method |
Publications (1)
Publication Number | Publication Date |
---|---|
PT1056542E true PT1056542E (en) | 2003-10-31 |
Family
ID=21831045
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT99908261T PT1056542E (en) | 1998-02-19 | 1999-02-19 | PARALLEL TRANSPORT MANDRIS USING REPULSIVE FIELD ORIENTATION |
Country Status (13)
Country | Link |
---|---|
US (1) | US6096368A (en) |
EP (1) | EP1056542B1 (en) |
JP (1) | JP2002503547A (en) |
KR (1) | KR20010041041A (en) |
AT (1) | ATE244607T1 (en) |
AU (1) | AU743087B2 (en) |
CA (1) | CA2321007A1 (en) |
DE (1) | DE69909441T2 (en) |
ES (1) | ES2203079T3 (en) |
HK (1) | HK1034051A1 (en) |
HU (1) | HUP0100782A3 (en) |
PT (1) | PT1056542E (en) |
WO (1) | WO1999042216A1 (en) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0907889B1 (en) | 1996-04-25 | 2007-07-04 | BioArray Solutions Ltd. | Light-controlled electrokinetic assembly of particles near surfaces |
US6182712B1 (en) | 1997-07-21 | 2001-02-06 | Inhale Therapeutic Systems | Power filling apparatus and methods for their use |
US6063194A (en) | 1998-06-10 | 2000-05-16 | Delsys Pharmaceutical Corporation | Dry powder deposition apparatus |
US6923979B2 (en) * | 1999-04-27 | 2005-08-02 | Microdose Technologies, Inc. | Method for depositing particles onto a substrate using an alternating electric field |
EP1207955A1 (en) * | 1999-08-27 | 2002-05-29 | Picogram, Inc. | Method and device for performing operations at charged microlocations |
US6295194B1 (en) * | 1999-09-10 | 2001-09-25 | Delsys Pharmaceutical Corporation | Bead or particle manipulating chucks |
US6427688B1 (en) * | 2000-02-01 | 2002-08-06 | Dura Pharmaceuticals, Icn. | Dry powder inhaler |
ES2259666T3 (en) | 2000-06-21 | 2006-10-16 | Bioarray Solutions Ltd | MOLECULAR ANALYSIS OF MULTIPLE ANALYTICS USING SERIES OF RANDOM PARTICLES WITH APPLICATION SPECIFICITY. |
US9709559B2 (en) | 2000-06-21 | 2017-07-18 | Bioarray Solutions, Ltd. | Multianalyte molecular analysis using application-specific random particle arrays |
US20020117753A1 (en) * | 2001-02-23 | 2002-08-29 | Lee Michael G. | Three dimensional packaging |
US7262063B2 (en) | 2001-06-21 | 2007-08-28 | Bio Array Solutions, Ltd. | Directed assembly of functional heterostructures |
US6686207B2 (en) | 2001-10-12 | 2004-02-03 | Massachusetts Institute Of Technology | Manipulating micron scale items |
US20040002073A1 (en) | 2001-10-15 | 2004-01-01 | Li Alice Xiang | Multiplexed analysis of polymorphic loci by concurrent interrogation and enzyme-mediated detection |
US7335153B2 (en) | 2001-12-28 | 2008-02-26 | Bio Array Solutions Ltd. | Arrays of microparticles and methods of preparation thereof |
EP1515890B1 (en) * | 2002-06-27 | 2012-07-11 | Novartis AG | Device and method for controlling the flow of a powder |
CA2497917A1 (en) * | 2002-09-13 | 2004-03-25 | Exelixis, Inc. | Apparatus for pipetting powder |
WO2004047007A1 (en) | 2002-11-15 | 2004-06-03 | Bioarray Solutions, Ltd. | Analysis, secure access to, and transmission of array images |
WO2005029705A2 (en) | 2003-09-18 | 2005-03-31 | Bioarray Solutions, Ltd. | Number coding for identification of subtypes of coded types of solid phase carriers |
JP4564959B2 (en) | 2003-09-22 | 2010-10-20 | バイオアレイ ソリューションズ リミテッド | Surface-immobilized polyelectrolyte with multiple functional groups that can be covalently bonded to biomolecules |
NZ547492A (en) | 2003-10-28 | 2009-12-24 | Bioarray Solutions Ltd | Optimization of gene expression analysis using immobilized capture probes of different lengths and densities |
PT1694859E (en) | 2003-10-29 | 2015-04-13 | Bioarray Solutions Ltd | Multiplexed nucleic acid analysis by fragmentation of double-stranded dna |
US7848889B2 (en) | 2004-08-02 | 2010-12-07 | Bioarray Solutions, Ltd. | Automated analysis of multiplexed probe-target interaction patterns: pattern matching and allele identification |
US8486629B2 (en) | 2005-06-01 | 2013-07-16 | Bioarray Solutions, Ltd. | Creation of functionalized microparticle libraries by oligonucleotide ligation or elongation |
US9105492B2 (en) | 2012-05-08 | 2015-08-11 | LuxVue Technology Corporation | Compliant micro device transfer head |
US9034754B2 (en) | 2012-05-25 | 2015-05-19 | LuxVue Technology Corporation | Method of forming a micro device transfer head with silicon electrode |
US8569115B1 (en) | 2012-07-06 | 2013-10-29 | LuxVue Technology Corporation | Method of forming a compliant bipolar micro device transfer head with silicon electrodes |
US9255001B2 (en) | 2012-12-10 | 2016-02-09 | LuxVue Technology Corporation | Micro device transfer head array with metal electrodes |
US9236815B2 (en) * | 2012-12-10 | 2016-01-12 | LuxVue Technology Corporation | Compliant micro device transfer head array with metal electrodes |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5028501A (en) * | 1989-06-14 | 1991-07-02 | Rca Licensing Corp. | Method of manufacturing a luminescent screen assembly using a dry-powdered filming material |
GB9301122D0 (en) * | 1993-01-21 | 1993-03-10 | Scient Generics Ltd | Method of analysis/separation |
US5788814A (en) * | 1996-04-09 | 1998-08-04 | David Sarnoff Research Center | Chucks and methods for positioning multiple objects on a substrate |
US5858099A (en) * | 1996-04-09 | 1999-01-12 | Sarnoff Corporation | Electrostatic chucks and a particle deposition apparatus therefor |
US5846595A (en) * | 1996-04-09 | 1998-12-08 | Sarnoff Corporation | Method of making pharmaceutical using electrostatic chuck |
US5728532A (en) * | 1996-05-31 | 1998-03-17 | Ackley; Donald E. | Electrode configuration for matrix addressing of a molecular detection device |
-
1998
- 1998-02-19 US US09/026,303 patent/US6096368A/en not_active Expired - Fee Related
-
1999
- 1999-02-19 ES ES99908261T patent/ES2203079T3/en not_active Expired - Lifetime
- 1999-02-19 KR KR1020007009074A patent/KR20010041041A/en not_active Application Discontinuation
- 1999-02-19 WO PCT/US1999/003575 patent/WO1999042216A1/en not_active Application Discontinuation
- 1999-02-19 AT AT99908261T patent/ATE244607T1/en not_active IP Right Cessation
- 1999-02-19 EP EP99908261A patent/EP1056542B1/en not_active Expired - Lifetime
- 1999-02-19 HU HU0100782A patent/HUP0100782A3/en unknown
- 1999-02-19 DE DE69909441T patent/DE69909441T2/en not_active Expired - Fee Related
- 1999-02-19 CA CA002321007A patent/CA2321007A1/en not_active Abandoned
- 1999-02-19 JP JP2000532215A patent/JP2002503547A/en not_active Withdrawn
- 1999-02-19 PT PT99908261T patent/PT1056542E/en unknown
- 1999-02-19 AU AU27739/99A patent/AU743087B2/en not_active Ceased
-
2001
- 2001-06-06 HK HK01103918A patent/HK1034051A1/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DE69909441T2 (en) | 2003-12-24 |
WO1999042216A8 (en) | 1999-11-04 |
EP1056542B1 (en) | 2003-07-09 |
HUP0100782A2 (en) | 2001-07-30 |
ES2203079T3 (en) | 2004-04-01 |
AU2773999A (en) | 1999-09-06 |
CA2321007A1 (en) | 1999-08-26 |
DE69909441D1 (en) | 2003-08-14 |
US6096368A (en) | 2000-08-01 |
HK1034051A1 (en) | 2001-10-12 |
JP2002503547A (en) | 2002-02-05 |
HUP0100782A3 (en) | 2002-10-28 |
EP1056542A1 (en) | 2000-12-06 |
KR20010041041A (en) | 2001-05-15 |
ATE244607T1 (en) | 2003-07-15 |
WO1999042216A1 (en) | 1999-08-26 |
AU743087B2 (en) | 2002-01-17 |
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