PT103003A - Set of medicinal metal enzyme high capacity inhibitors comprises succinic and iminodiacetic acids giving high zinc and nickel ion complexing capacity - Google Patents
Set of medicinal metal enzyme high capacity inhibitors comprises succinic and iminodiacetic acids giving high zinc and nickel ion complexing capacityInfo
- Publication number
- PT103003A PT103003A PT103003A PT103003A PT103003A PT 103003 A PT103003 A PT 103003A PT 103003 A PT103003 A PT 103003A PT 103003 A PT103003 A PT 103003A PT 103003 A PT103003 A PT 103003A
- Authority
- PT
- Portugal
- Prior art keywords
- capacity
- ion complexing
- nickel ion
- inhibitors comprises
- metal enzyme
- Prior art date
Links
- 102000004190 Enzymes Human genes 0.000 title abstract 2
- 108090000790 Enzymes Proteins 0.000 title abstract 2
- 230000000536 complexating effect Effects 0.000 title abstract 2
- NBZBKCUXIYYUSX-UHFFFAOYSA-N iminodiacetic acid Chemical class OC(=O)CNCC(O)=O NBZBKCUXIYYUSX-UHFFFAOYSA-N 0.000 title abstract 2
- 239000003112 inhibitor Substances 0.000 title abstract 2
- 239000002184 metal Substances 0.000 title abstract 2
- 229910052751 metal Inorganic materials 0.000 title abstract 2
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 title 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 title 1
- 229910001453 nickel ion Inorganic materials 0.000 title 1
- 229910052725 zinc Inorganic materials 0.000 title 1
- 239000011701 zinc Substances 0.000 title 1
- 241000894006 Bacteria Species 0.000 abstract 1
- 102000005741 Metalloproteases Human genes 0.000 abstract 1
- 108010006035 Metalloproteases Proteins 0.000 abstract 1
- PTFCDOFLOPIGGS-UHFFFAOYSA-N Zinc dication Chemical compound [Zn+2] PTFCDOFLOPIGGS-UHFFFAOYSA-N 0.000 abstract 1
- 125000000524 functional group Chemical group 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 150000002500 ions Chemical class 0.000 abstract 1
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Set of medicinal metal enzyme high capacity inhibitors comprises succinic and iminodiacetic acids containing at least one hydroxamate group and functional groups or moelcular residues. The Zn (II) and Ni (II) ion complexing capacity is high, for inhibiting metalloproteinases (matrices and bacteria pharmacology).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PT103003A PT103003A (en) | 2003-08-04 | 2003-08-04 | Set of medicinal metal enzyme high capacity inhibitors comprises succinic and iminodiacetic acids giving high zinc and nickel ion complexing capacity |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PT103003A PT103003A (en) | 2003-08-04 | 2003-08-04 | Set of medicinal metal enzyme high capacity inhibitors comprises succinic and iminodiacetic acids giving high zinc and nickel ion complexing capacity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT103003A true PT103003A (en) | 2005-02-28 |
Family
ID=34836875
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT103003A PT103003A (en) | 2003-08-04 | 2003-08-04 | Set of medicinal metal enzyme high capacity inhibitors comprises succinic and iminodiacetic acids giving high zinc and nickel ion complexing capacity |
Country Status (1)
| Country | Link |
|---|---|
| PT (1) | PT103003A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9700599B2 (en) | 2012-11-13 | 2017-07-11 | Adocia | Rapid-acting insulin formulation comprising a substituted anionic compound |
| US9795678B2 (en) | 2014-05-14 | 2017-10-24 | Adocia | Fast-acting insulin composition comprising a substituted anionic compound and a polyanionic compound |
| US10525133B2 (en) | 2014-05-14 | 2020-01-07 | Adocia | Aqueous composition comprising at least one protein and one solubilizing agent, preparation thereof and uses thereof |
| US10792335B2 (en) | 2015-11-16 | 2020-10-06 | Adocia | Rapid-acting insulin composition comprising a substituted citrate |
-
2003
- 2003-08-04 PT PT103003A patent/PT103003A/en active IP Right Grant
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9700599B2 (en) | 2012-11-13 | 2017-07-11 | Adocia | Rapid-acting insulin formulation comprising a substituted anionic compound |
| US10583175B2 (en) | 2012-11-13 | 2020-03-10 | Adocia | Rapid-acting insulin formulation comprising a substituted anionic compound |
| US10646551B2 (en) | 2012-11-13 | 2020-05-12 | Adocia | Rapid-acting insulin formulation comprising a substituted anionic compound |
| US10881716B2 (en) | 2012-11-13 | 2021-01-05 | Adocia | Rapid-acting insulin formulation comprising a substituted anionic compound |
| US11324808B2 (en) | 2012-11-13 | 2022-05-10 | Adocia | Rapid-acting insulin formulation comprising a substituted anionic compound |
| US9795678B2 (en) | 2014-05-14 | 2017-10-24 | Adocia | Fast-acting insulin composition comprising a substituted anionic compound and a polyanionic compound |
| US10525133B2 (en) | 2014-05-14 | 2020-01-07 | Adocia | Aqueous composition comprising at least one protein and one solubilizing agent, preparation thereof and uses thereof |
| US10792335B2 (en) | 2015-11-16 | 2020-10-06 | Adocia | Rapid-acting insulin composition comprising a substituted citrate |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BB1A | Laying open of patent application |
Effective date: 20040129 |
|
| FG3A | Patent granted, date of granting |
Effective date: 20050804 |