PT101316A - Prepn. of 2,3-di:hydro-5-beta-1H-imidazol-1-yl-ethoxy-1H-indene-1-carboxylic acid - having antithrombotic and anti-platelet aggregation activity - Google Patents
Prepn. of 2,3-di:hydro-5-beta-1H-imidazol-1-yl-ethoxy-1H-indene-1-carboxylic acid - having antithrombotic and anti-platelet aggregation activityInfo
- Publication number
- PT101316A PT101316A PT10131693A PT10131693A PT101316A PT 101316 A PT101316 A PT 101316A PT 10131693 A PT10131693 A PT 10131693A PT 10131693 A PT10131693 A PT 10131693A PT 101316 A PT101316 A PT 101316A
- Authority
- PT
- Portugal
- Prior art keywords
- prepn
- imidazol
- ethoxy
- beta
- acid
- Prior art date
Links
Abstract
Prepn. of 2,3-dihydro-5-(beta -(1H-imidazol- 1-yl)ethoxy)-1H-inden-1-carboxylic acid comprises reacting 5-methoxy-1-indanone with trimethyl silylcyanate in the presence of a Lewis acid; acid hydrolysis; treating with trichlorate in acid medium; acid demethylation; esterification with an aliphatic alcohol; alkylation with 2-chloroethylsulphonate; reaction with imidazole and finally hydrolysing using mineral acid.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PT10131693A PT101316B (en) | 1993-07-26 | 1993-07-26 | METHOD OF PREPARING 2,3-DIHYDRO-5- (BETA (1H-IMIDAZOL-1-YL) ETOXY) -1H-INDEN-1-CARBOXYLIC ACID |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PT10131693A PT101316B (en) | 1993-07-26 | 1993-07-26 | METHOD OF PREPARING 2,3-DIHYDRO-5- (BETA (1H-IMIDAZOL-1-YL) ETOXY) -1H-INDEN-1-CARBOXYLIC ACID |
Publications (2)
Publication Number | Publication Date |
---|---|
PT101316A true PT101316A (en) | 1995-01-31 |
PT101316B PT101316B (en) | 1999-09-30 |
Family
ID=20085302
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT10131693A PT101316B (en) | 1993-07-26 | 1993-07-26 | METHOD OF PREPARING 2,3-DIHYDRO-5- (BETA (1H-IMIDAZOL-1-YL) ETOXY) -1H-INDEN-1-CARBOXYLIC ACID |
Country Status (1)
Country | Link |
---|---|
PT (1) | PT101316B (en) |
-
1993
- 1993-07-26 PT PT10131693A patent/PT101316B/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
PT101316B (en) | 1999-09-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
BB1A | Laying open of patent application |
Effective date: 19931018 |
|
FG3A | Patent granted, date of granting |
Effective date: 19990628 |
|
MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 20021231 |