PT101316A - Prepn. of 2,3-di:hydro-5-beta-1H-imidazol-1-yl-ethoxy-1H-indene-1-carboxylic acid - having antithrombotic and anti-platelet aggregation activity - Google Patents

Prepn. of 2,3-di:hydro-5-beta-1H-imidazol-1-yl-ethoxy-1H-indene-1-carboxylic acid - having antithrombotic and anti-platelet aggregation activity

Info

Publication number
PT101316A
PT101316A PT10131693A PT10131693A PT101316A PT 101316 A PT101316 A PT 101316A PT 10131693 A PT10131693 A PT 10131693A PT 10131693 A PT10131693 A PT 10131693A PT 101316 A PT101316 A PT 101316A
Authority
PT
Portugal
Prior art keywords
prepn
imidazol
ethoxy
beta
acid
Prior art date
Application number
PT10131693A
Other languages
Portuguese (pt)
Other versions
PT101316B (en
Inventor
Rafael Foquet
Josep M Castello
Jose A Ortiz
Aurelio Sacristan
Original Assignee
Ferrer Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferrer Int filed Critical Ferrer Int
Priority to PT10131693A priority Critical patent/PT101316B/en
Publication of PT101316A publication Critical patent/PT101316A/en
Publication of PT101316B publication Critical patent/PT101316B/en

Links

Abstract

Prepn. of 2,3-dihydro-5-(beta -(1H-imidazol- 1-yl)ethoxy)-1H-inden-1-carboxylic acid comprises reacting 5-methoxy-1-indanone with trimethyl silylcyanate in the presence of a Lewis acid; acid hydrolysis; treating with trichlorate in acid medium; acid demethylation; esterification with an aliphatic alcohol; alkylation with 2-chloroethylsulphonate; reaction with imidazole and finally hydrolysing using mineral acid.
PT10131693A 1993-07-26 1993-07-26 METHOD OF PREPARING 2,3-DIHYDRO-5- (BETA (1H-IMIDAZOL-1-YL) ETOXY) -1H-INDEN-1-CARBOXYLIC ACID PT101316B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PT10131693A PT101316B (en) 1993-07-26 1993-07-26 METHOD OF PREPARING 2,3-DIHYDRO-5- (BETA (1H-IMIDAZOL-1-YL) ETOXY) -1H-INDEN-1-CARBOXYLIC ACID

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PT10131693A PT101316B (en) 1993-07-26 1993-07-26 METHOD OF PREPARING 2,3-DIHYDRO-5- (BETA (1H-IMIDAZOL-1-YL) ETOXY) -1H-INDEN-1-CARBOXYLIC ACID

Publications (2)

Publication Number Publication Date
PT101316A true PT101316A (en) 1995-01-31
PT101316B PT101316B (en) 1999-09-30

Family

ID=20085302

Family Applications (1)

Application Number Title Priority Date Filing Date
PT10131693A PT101316B (en) 1993-07-26 1993-07-26 METHOD OF PREPARING 2,3-DIHYDRO-5- (BETA (1H-IMIDAZOL-1-YL) ETOXY) -1H-INDEN-1-CARBOXYLIC ACID

Country Status (1)

Country Link
PT (1) PT101316B (en)

Also Published As

Publication number Publication date
PT101316B (en) 1999-09-30

Similar Documents

Publication Publication Date Title
MX9703063A (en) Boronic ester and acid compounds, synthesis and uses.
MX9605678A (en) Process for producing active agent preparations in the form of a solid solution of the active agent in a polymer matrix and active agent preparations obtained thereby.
AU4887393A (en) Method of inhibiting corrosion in aqueous systems
PT101316A (en) Prepn. of 2,3-di:hydro-5-beta-1H-imidazol-1-yl-ethoxy-1H-indene-1-carboxylic acid - having antithrombotic and anti-platelet aggregation activity
ES8507460A1 (en) Process for esterifying 3,5-ditert-butyl-4-hydroxybenzoic acid.
ES8800300A1 (en) Water reducible coating compositions
HU0004999D0 (en) Process for the saponification of the pettidester
AU2845289A (en) Process for preparing 1-hydroxyalkyl-5-nitroimidazoles
MX9703766A (en) Process for preparation of 5-hydroxymethylthiazole.
AU1329895A (en) Metallic implant and process for treating a metallic implant
AU629790B3 (en) An electrochemical process employing a modified polymeric foam to enhance the recoverability of metal values from solution
MX9603946A (en) Chemical castration.
MX9505078A (en) Processs for the preparation of alkyl halogendifluoracetates.
CA2177888A1 (en) Continuous process for the manufacture of sodium c4-c8alkoxide
ES8609424A1 (en) Hydrated catalyst complex and process.
AU2845389A (en) Process for preparing 1-hydroxyalkyl-2-methyl-5- nitroimidazoles
HUT49381A (en) Electrolyte for galvanization
ES2001715A6 (en) Water-proof paper support for photographic purposes.
GR3018712T3 (en) Process for the preparation of n-formyl-l-aspartic anhydride
TW249214B (en) Process of moistening surface-printing
MX9705919A (en) A method of preparing an undifferentiated cell.
GB2315068B (en) Preparation of 4,4,4-trichloro-butan-1-ol
GB9507659D0 (en) Alkylation process
UA15491A (en) Process for the preparation of isopropyl naphthalene
TW363958B (en) Process for producing alpha-(tert-alkyl) cyanoacetic acid ester

Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19931018

FG3A Patent granted, date of granting

Effective date: 19990628

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20021231