PT100913A - Prepn. of erythromycin 9-(O-((2-methoxy ethoxy)methyl)oxime - used as antibiotic active against Gram positive bacteria - Google Patents

Prepn. of erythromycin 9-(O-((2-methoxy ethoxy)methyl)oxime - used as antibiotic active against Gram positive bacteria

Info

Publication number
PT100913A
PT100913A PT10091392A PT10091392A PT100913A PT 100913 A PT100913 A PT 100913A PT 10091392 A PT10091392 A PT 10091392A PT 10091392 A PT10091392 A PT 10091392A PT 100913 A PT100913 A PT 100913A
Authority
PT
Portugal
Prior art keywords
erythromycin
oxime
prepn
methyl
methoxy ethoxy
Prior art date
Application number
PT10091392A
Other languages
Portuguese (pt)
Inventor
Alba Agusti Cruz
Eduard Elias Vilarelle
Antonio Ginebreda Marti
Original Assignee
Prodesfarma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prodesfarma Sa filed Critical Prodesfarma Sa
Publication of PT100913A publication Critical patent/PT100913A/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Prepn. of erythromycin 9-(O-((2-methoxy ethoxy)methyl)oxime) (roxitromicin) (I) comprises treating a 2-methoxy-ethoxymethyl ammonium salt of erythromycin-9-oxime of formula (V) (where X is an anion derived from an acid). Reaction is in a non alcoholic polar solvent.
PT10091392A 1991-10-01 1992-09-29 Prepn. of erythromycin 9-(O-((2-methoxy ethoxy)methyl)oxime - used as antibiotic active against Gram positive bacteria PT100913A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9102152A ES2036472B1 (en) 1991-10-01 1991-10-01 PROCEDURE FOR OBTAINING ERYTHROMYCIN 9- (0 - ((2-METOXYETOXI) METHYL) OXIME) (ROXYTHROMYCIN).

Publications (1)

Publication Number Publication Date
PT100913A true PT100913A (en) 1993-11-30

Family

ID=8273673

Family Applications (1)

Application Number Title Priority Date Filing Date
PT10091392A PT100913A (en) 1991-10-01 1992-09-29 Prepn. of erythromycin 9-(O-((2-methoxy ethoxy)methyl)oxime - used as antibiotic active against Gram positive bacteria

Country Status (2)

Country Link
ES (1) ES2036472B1 (en)
PT (1) PT100913A (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT102202B (en) 1998-09-10 2001-04-30 Hovione Sociedade Quimica S A PROCESS FOR THE PURIFICATION OF ROXITROMYCIN
EP1004591B1 (en) * 1998-11-24 2003-04-09 Max India Limited Process for preparing roxithromycin and derivatives thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2473525A1 (en) * 1980-01-11 1981-07-17 Roussel Uclaf NOVEL OXIMES DERIVED FROM ERYTHROMYCIN, PROCESS FOR PREPARING THEM AND THEIR APPLICATION AS MEDICAMENTS

Also Published As

Publication number Publication date
ES2036472B1 (en) 1994-03-01
ES2036472A1 (en) 1993-05-16

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Effective date: 19990408