PT100429A - Use of xanthine derivatives in the preparation of a medication for inhibition of the production of tumour necrosis factor - Google Patents
Use of xanthine derivatives in the preparation of a medication for inhibition of the production of tumour necrosis factorInfo
- Publication number
- PT100429A PT100429A PT10042992A PT10042992A PT100429A PT 100429 A PT100429 A PT 100429A PT 10042992 A PT10042992 A PT 10042992A PT 10042992 A PT10042992 A PT 10042992A PT 100429 A PT100429 A PT 100429A
- Authority
- PT
- Portugal
- Prior art keywords
- medication
- inhibition
- preparation
- production
- necrosis factor
- Prior art date
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The present invention relates to the use of 8-substituted xanthines of formula I: <IMAGE> in which R1 and R2 each independently of the other represent alkyl or -(CH2)m-A; m represents zero or a whole number 1, 2 or 3; A represents a cyclic hydrocarbon radical, substituted or unsubstituted; R3 represents a halogen atom, a nitro group or an -NR4R5 group; R4 and R5 each independently of the other represent hydrogen, alkyl or alkylcarbonyl; or R4 and R5 together with the nitrogen to which they are bound form an optionally substituted heterocyclic group; and the pharmaceutically acceptable salts thereof in the preparation of a medication for inhibition of the production of tumour necrosis factor (TNF).
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PT10042992A PT100429B (en) | 1992-04-28 | 1992-04-28 | USE OF XANTIN DERIVATIVES IN THE PREPARATION OF A MEDICATION FOR INHIBITION OF THE PRODUCTION OF TUMOR NECROSIS FACTOR |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PT10042992A PT100429B (en) | 1992-04-28 | 1992-04-28 | USE OF XANTIN DERIVATIVES IN THE PREPARATION OF A MEDICATION FOR INHIBITION OF THE PRODUCTION OF TUMOR NECROSIS FACTOR |
Publications (2)
Publication Number | Publication Date |
---|---|
PT100429A true PT100429A (en) | 1993-10-29 |
PT100429B PT100429B (en) | 1999-10-29 |
Family
ID=20085139
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT10042992A PT100429B (en) | 1992-04-28 | 1992-04-28 | USE OF XANTIN DERIVATIVES IN THE PREPARATION OF A MEDICATION FOR INHIBITION OF THE PRODUCTION OF TUMOR NECROSIS FACTOR |
Country Status (1)
Country | Link |
---|---|
PT (1) | PT100429B (en) |
-
1992
- 1992-04-28 PT PT10042992A patent/PT100429B/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
PT100429B (en) | 1999-10-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
BB1A | Laying open of patent application |
Effective date: 19930326 |
|
FG3A | Patent granted, date of granting |
Effective date: 19990715 |
|
MM4A | Annulment/lapse due to non-payment of fees;searched & examined patent |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 20130115 |