PL84880B1 - - Google Patents

Info

Publication number

PL84880B1

PL84880B1 PL15685669A PL15685669A PL84880B1 PL 84880 B1 PL84880 B1 PL 84880B1 PL 15685669 A PL15685669 A PL 15685669A PL 15685669 A PL15685669 A PL 15685669A PL 84880 B1 PL84880 B1 PL 84880B1

Authority

PL

Poland

Prior art keywords

formula

radical

compound

carbon atoms

group

Prior art date

1969-01-28

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• 150000001875 compounds Chemical class 0.000 claims description 7
• -1 alkyl radical Chemical class 0.000 claims description 6
• 238000000034 method Methods 0.000 claims description 6
• 125000004432 carbon atom Chemical group C* 0.000 claims description 4
• 125000003545 alkoxy group Chemical group 0.000 claims description 2
• 125000003277 amino group Chemical group 0.000 claims description 2
• 150000001735 carboxylic acids Chemical class 0.000 claims description 2
• 125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 2
• 125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 2
• WCYWZMWISLQXQU-UHFFFAOYSA-N methyl Chemical compound [CH3] WCYWZMWISLQXQU-UHFFFAOYSA-N 0.000 claims description 2
• LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 claims description 2
• VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 claims 1
• 239000005977 Ethylene Substances 0.000 claims 1
• 125000003118 aryl group Chemical group 0.000 claims 1
• 125000004104 aryloxy group Chemical group 0.000 claims 1
• 235000013877 carbamide Nutrition 0.000 claims 1
• 229910052736 halogen Inorganic materials 0.000 claims 1
• 150000002367 halogens Chemical class 0.000 claims 1
• 150000003254 radicals Chemical class 0.000 claims 1
• 150000003672 ureas Chemical class 0.000 claims 1
• JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 description 2
• 229910052783 alkali metal Inorganic materials 0.000 description 2
• 150000001412 amines Chemical class 0.000 description 2
• 239000008280 blood Substances 0.000 description 2
• 210000004369 blood Anatomy 0.000 description 2
• NGNBDVOYPDDBFK-UHFFFAOYSA-N 2-[2,4-di(pentan-2-yl)phenoxy]acetyl chloride Chemical compound CCCC(C)C1=CC=C(OCC(Cl)=O)C(C(C)CCC)=C1 NGNBDVOYPDDBFK-UHFFFAOYSA-N 0.000 description 1
• YUTQRQJTFPEEPB-UHFFFAOYSA-N 4-methyl-1,2-thiazole Chemical compound CC=1C=NSC=1 YUTQRQJTFPEEPB-UHFFFAOYSA-N 0.000 description 1
• OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
• ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 1
• JLRGJRBPOGGCBT-UHFFFAOYSA-N Tolbutamide Chemical compound CCCCNC(=O)NS(=O)(=O)C1=CC=C(C)C=C1 JLRGJRBPOGGCBT-UHFFFAOYSA-N 0.000 description 1
• OHBTULDTCSOWOY-UHFFFAOYSA-N [C].C=C Chemical compound [C].C=C OHBTULDTCSOWOY-UHFFFAOYSA-N 0.000 description 1
• 239000002253 acid Substances 0.000 description 1
• 150000007513 acids Chemical class 0.000 description 1
• 150000001340 alkali metals Chemical class 0.000 description 1
• 125000004391 aryl sulfonyl group Chemical group 0.000 description 1
• 229910052799 carbon Inorganic materials 0.000 description 1
• 238000006243 chemical reaction Methods 0.000 description 1
• 229910052801 chlorine Inorganic materials 0.000 description 1
• 239000000460 chlorine Substances 0.000 description 1
• NISGSNTVMOOSJQ-UHFFFAOYSA-N cyclopentanamine Chemical compound NC1CCCC1 NISGSNTVMOOSJQ-UHFFFAOYSA-N 0.000 description 1
• 206010012601 diabetes mellitus Diseases 0.000 description 1
• 239000003814 drug Substances 0.000 description 1
• 230000000694 effects Effects 0.000 description 1
• 125000005843 halogen group Chemical group 0.000 description 1
• 239000000543 intermediate Substances 0.000 description 1
• 239000011159 matrix material Substances 0.000 description 1
• 229940126701 oral medication Drugs 0.000 description 1
• 125000003170 phenylsulfonyl group Chemical group C1(=CC=CC=C1)S(=O)(=O)* 0.000 description 1
• UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 description 1
• 238000000926 separation method Methods 0.000 description 1
• 239000007858 starting material Substances 0.000 description 1
• 229940124597 therapeutic agent Drugs 0.000 description 1
• 229960005371 tolbutamide Drugs 0.000 description 1