PL4536675T3 - Sposób oczyszczania 2-metoksyestradiolu z 4-metoksyestradiolu i produkty pośrednie sposobu - Google Patents

Sposób oczyszczania 2-metoksyestradiolu z 4-metoksyestradiolu i produkty pośrednie sposobu

Info

Publication number
PL4536675T3
PL4536675T3 PL23738863.2T PL23738863T PL4536675T3 PL 4536675 T3 PL4536675 T3 PL 4536675T3 PL 23738863 T PL23738863 T PL 23738863T PL 4536675 T3 PL4536675 T3 PL 4536675T3
Authority
PL
Poland
Prior art keywords
methoxyestradiol
intermediates
purification
Prior art date
Application number
PL23738863.2T
Other languages
English (en)
Inventor
Roberto Lenna
Claudio DELFRATE
Davide RIGAMONTI
Michele BOGHI
Original Assignee
Industriale Chimica S.R.L.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT102022000012425A external-priority patent/IT202200012425A1/it
Priority claimed from IT102022000020784A external-priority patent/IT202200020784A1/it
Application filed by Industriale Chimica S.R.L. filed Critical Industriale Chimica S.R.L.
Publication of PL4536675T3 publication Critical patent/PL4536675T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0066—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
    • C07J1/007—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0066—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
    • C07J1/007—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • C07J1/0074—Esters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
PL23738863.2T 2022-06-13 2023-06-12 Sposób oczyszczania 2-metoksyestradiolu z 4-metoksyestradiolu i produkty pośrednie sposobu PL4536675T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT102022000012425A IT202200012425A1 (it) 2022-06-13 2022-06-13 Processo per la purificazione di 2-metossiestradiolo da 4-metossiestradiolo ed intermedio del processo
IT102022000020784A IT202200020784A1 (it) 2022-10-10 2022-10-10 Processo per la purificazione di 2-metossiestradiolo da 4-metossiestradiolo ed intermedi del processo
PCT/IB2023/056042 WO2023242712A1 (en) 2022-06-13 2023-06-12 Process for the purification of 2-methoxyestradiol from 4- methoxyestradiol and intermediates of the process

Publications (1)

Publication Number Publication Date
PL4536675T3 true PL4536675T3 (pl) 2026-07-06

Family

ID=87158123

Family Applications (1)

Application Number Title Priority Date Filing Date
PL23738863.2T PL4536675T3 (pl) 2022-06-13 2023-06-12 Sposób oczyszczania 2-metoksyestradiolu z 4-metoksyestradiolu i produkty pośrednie sposobu

Country Status (7)

Country Link
EP (1) EP4536675B1 (pl)
CN (1) CN119894916A (pl)
CA (1) CA3259059A1 (pl)
ES (1) ES3066722T3 (pl)
FR (1) FR3136464B1 (pl)
PL (1) PL4536675T3 (pl)
WO (1) WO2023242712A1 (pl)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN122171728B (zh) * 2026-05-13 2026-07-17 广东长隆集团有限公司 一种利用糠酰氯衍生-液相色谱串联质谱检测类固醇激素的方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7572600A (en) * 1999-08-23 2001-03-19 Entremed, Inc Methods of obtaining 2-methoxyestradiol of high purity
AUPQ342599A0 (en) * 1999-10-14 1999-11-04 University Of Melbourne, The Conjugates and uses thereof

Also Published As

Publication number Publication date
CA3259059A1 (en) 2023-12-21
ES3066722T3 (en) 2026-05-14
FR3136464A1 (fr) 2023-12-15
EP4536675B1 (en) 2026-01-21
FR3136464B1 (fr) 2026-04-10
EP4536675A1 (en) 2025-04-16
WO2023242712A1 (en) 2023-12-21
CN119894916A (zh) 2025-04-25