PL4536187T3 - Kompozycje zawierające 5,10-metyleno-(6r)-tetrahydrofolian disodowy - Google Patents
Kompozycje zawierające 5,10-metyleno-(6r)-tetrahydrofolian disodowyInfo
- Publication number
- PL4536187T3 PL4536187T3 PL23730517.2T PL23730517T PL4536187T3 PL 4536187 T3 PL4536187 T3 PL 4536187T3 PL 23730517 T PL23730517 T PL 23730517T PL 4536187 T3 PL4536187 T3 PL 4536187T3
- Authority
- PL
- Poland
- Prior art keywords
- tetrahydrofolate
- disodium
- methylene
- compositions
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1611—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP22177932 | 2022-06-08 | ||
| PCT/EP2023/064972 WO2023237484A1 (en) | 2022-06-08 | 2023-06-05 | Compositions comprising disodium 5,10-methylene-(6r)-tetrahydrofolate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL4536187T3 true PL4536187T3 (pl) | 2026-05-04 |
Family
ID=81984853
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL23730517.2T PL4536187T3 (pl) | 2022-06-08 | 2023-06-05 | Kompozycje zawierające 5,10-metyleno-(6r)-tetrahydrofolian disodowy |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20250360135A1 (cg-RX-API-DMAC10.html) |
| EP (2) | EP4706775A3 (cg-RX-API-DMAC10.html) |
| JP (1) | JP7894470B2 (cg-RX-API-DMAC10.html) |
| KR (1) | KR20250022145A (cg-RX-API-DMAC10.html) |
| CN (1) | CN119365186A (cg-RX-API-DMAC10.html) |
| AU (1) | AU2023282347A1 (cg-RX-API-DMAC10.html) |
| CA (1) | CA3258734A1 (cg-RX-API-DMAC10.html) |
| ES (1) | ES3069418T3 (cg-RX-API-DMAC10.html) |
| IL (1) | IL317395A (cg-RX-API-DMAC10.html) |
| PL (1) | PL4536187T3 (cg-RX-API-DMAC10.html) |
| WO (1) | WO2023237484A1 (cg-RX-API-DMAC10.html) |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1215945A (en) | 1983-03-20 | 1986-12-30 | Bengt Gustavsson | Fluid transfer system |
| CH682664A5 (en) | 1991-10-15 | 1993-10-29 | Eprova Ag | Stable salts of 5,10-methylene tetrahydrofolate. |
| ATE262799T1 (de) * | 1996-01-31 | 2004-04-15 | Univ South Alabama | Lebensmittel und vitamin herstellungen mit natürlichem isomeren von reduzierten folaten |
| CH696628A5 (de) | 2002-02-26 | 2007-08-31 | Eprova Ag | Verwendung von Folaten zur Herstellung einer Zubereitung geeignet zur Vorbeugung und Behandlung von Entzündungen und entzündungsassoziierter Krankheiten, im Speziellen zur Beeinflussung der |
| CH697021A5 (de) * | 2003-06-26 | 2008-03-31 | Merck Eprova Ag | Stabile pharmazeutische Zusammensetzungen von 5, 10-Methylentetrahydrofolat. |
| WO2007064968A2 (en) | 2005-12-02 | 2007-06-07 | Adventrx Pharmaceuticals, Inc. | Stable pharmaceutical compositions of 5,10 methylenetetrahydrofolate |
| JP6235779B2 (ja) | 2012-03-28 | 2017-11-22 | 株式会社コーセー | 葉酸含有組成物及び葉酸の安定化方法 |
| EP2799061A1 (en) | 2013-04-30 | 2014-11-05 | Aprofol AG | Stable high dose pharmaceutical composition containing folates |
| EP2837631A1 (en) | 2013-08-14 | 2015-02-18 | Merck & Cie | New stable salt of 5,10-methylene-(6R)-tetrahydrofolic acid |
| US10059710B2 (en) * | 2016-02-17 | 2018-08-28 | Merck & Cie | Stable formulations of 5,10-methylene-(6R)-tetrahydrofolic acid |
| PT3668516T (pt) * | 2017-08-16 | 2021-12-23 | Merck Patent Gmbh | Liofilizados estáveis que compreendem ácido 5,10-metileno-(6r)-tetra-hidrofólico e um ácido dicarboxílico |
| CN107892692A (zh) * | 2017-12-28 | 2018-04-10 | 华东理工大学 | (6s)‑5‑甲基四氢叶酸锌盐的制备方法及其应用 |
-
2023
- 2023-06-05 WO PCT/EP2023/064972 patent/WO2023237484A1/en not_active Ceased
- 2023-06-05 CA CA3258734A patent/CA3258734A1/en active Pending
- 2023-06-05 ES ES23730517T patent/ES3069418T3/es active Active
- 2023-06-05 EP EP26153960.5A patent/EP4706775A3/en active Pending
- 2023-06-05 EP EP23730517.2A patent/EP4536187B1/en active Active
- 2023-06-05 US US18/872,672 patent/US20250360135A1/en active Pending
- 2023-06-05 KR KR1020257000562A patent/KR20250022145A/ko active Pending
- 2023-06-05 AU AU2023282347A patent/AU2023282347A1/en active Pending
- 2023-06-05 PL PL23730517.2T patent/PL4536187T3/pl unknown
- 2023-06-05 IL IL317395A patent/IL317395A/en unknown
- 2023-06-05 CN CN202380045351.1A patent/CN119365186A/zh active Pending
- 2023-06-05 JP JP2024570947A patent/JP7894470B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP4536187C0 (en) | 2026-01-28 |
| EP4536187B1 (en) | 2026-01-28 |
| EP4706775A2 (en) | 2026-03-11 |
| EP4536187A1 (en) | 2025-04-16 |
| IL317395A (en) | 2025-02-01 |
| CA3258734A1 (en) | 2023-12-14 |
| WO2023237484A1 (en) | 2023-12-14 |
| AU2023282347A1 (en) | 2025-01-16 |
| EP4706775A3 (en) | 2026-06-10 |
| JP7894470B2 (ja) | 2026-07-23 |
| KR20250022145A (ko) | 2025-02-14 |
| CN119365186A (zh) | 2025-01-24 |
| ES3069418T3 (en) | 2026-06-08 |
| US20250360135A1 (en) | 2025-11-27 |
| JP2025518274A (ja) | 2025-06-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL315791A (en) | compositions | |
| GB202319163D0 (en) | Compositions | |
| IL317503A (en) | Risankizumab compositions | |
| EP4536187C0 (en) | COMPOSITIONS CONTAINING 5,10-METHYLENE-(6R)-DISODIC TETRAHYDROFOLATE | |
| IL315870A (en) | The compounds containing cannabinoids | |
| CA244734S (en) | Figurine | |
| CA235189S (en) | Figurine | |
| GB202213970D0 (en) | 5000%vv3davtripple4000x10,000xshohryakuvaixonevaivai137millioncirclexdotshohryakuvaizonevai Shohryakuvaizonevaivai13millioncirclexdotgagaligagaligalifaligalig | |
| GB202213971D0 (en) | 5000%vv3davtripple4000x10,000xshohryakuvai137millioncirclexdotshohryakuvaizonevai shohryakuvaizonevaivai13millioncircleexdotgagaligagaligaligaligaligalishohry | |
| GB202213972D0 (en) | 5000%vv3davtripple4000x10,000xshohryakuvaizonevaivai137millioncirclexdot shohryakuvaivai13millioncirclexdotgagaligagaligaligaligaligaalishohryakuvaishohryakuv | |
| IL317418A (en) | Stable pharmaceutical preparations comprising 5,10-methylene-(6R)-tetrahydrofolic acid and NaCl | |
| GB202215342D0 (en) | 5000%nanoakattamakkunzokkukumTITLE too long | |
| HK40119541A (en) | Amusement machine of the pusher type | |
| GB202511471D0 (en) | Exosome-based compositions | |
| GB202510664D0 (en) | Compositions | |
| GB202505602D0 (en) | Compositions | |
| GB202500743D0 (en) | Compositions | |
| GB202411739D0 (en) | Compositions | |
| GB202407447D0 (en) | Aquafeed compositions | |
| GB202404395D0 (en) | Compositions | |
| CA3298060A1 (en) | Lubricant compositions | |
| GB202413620D0 (en) | Aquafeed compositions | |
| GB202403478D0 (en) | Compositions | |
| GB202409568D0 (en) | Application number-GB2400964.9 | |
| GB202319731D0 (en) | Compositions |