PL449419A1 - Cykliczne peptydy do zastosowania jako inhibitory furyny przeciwko wirusom z rodzaju Flavivirus i wirusom z rodziny Herpesviridae - Google Patents

Cykliczne peptydy do zastosowania jako inhibitory furyny przeciwko wirusom z rodzaju Flavivirus i wirusom z rodziny Herpesviridae

Info

Publication number
PL449419A1
PL449419A1 PL449419A PL44941924A PL449419A1 PL 449419 A1 PL449419 A1 PL 449419A1 PL 449419 A PL449419 A PL 449419A PL 44941924 A PL44941924 A PL 44941924A PL 449419 A1 PL449419 A1 PL 449419A1
Authority
PL
Poland
Prior art keywords
viruses
cyclic peptides
inhibitors against
furin inhibitors
genus flavivirus
Prior art date
Application number
PL449419A
Other languages
English (en)
Inventor
Dawid Dębowski
Agata Gitlin-Domagalska
Aleksandra Helbik-Maciejewska
Gabriela Brzuska
Andrea Lipińska
Krzysztof Rolka
Ewelina Król
Original Assignee
Uniwersytet Gdański
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uniwersytet Gdański filed Critical Uniwersytet Gdański
Priority to PL449419A priority Critical patent/PL449419A1/pl
Publication of PL449419A1 publication Critical patent/PL449419A1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Zgłoszenie dotyczy cyklicznych peptydów — bicyklicznych o wzorze ogólnym 1 i monocyklicznych o wzorze ogólnym 2 do zastosowania jako inhibitory furyny przeciwko wirusom rodzaju Flavivirus i wirusom z rodziny Herpesviridae, zwłaszcza przeciwko wirusowi Zika (ZIKV) i wirusowi BHV-1.
PL449419A 2024-07-31 2024-07-31 Cykliczne peptydy do zastosowania jako inhibitory furyny przeciwko wirusom z rodzaju Flavivirus i wirusom z rodziny Herpesviridae PL449419A1 (pl)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL449419A PL449419A1 (pl) 2024-07-31 2024-07-31 Cykliczne peptydy do zastosowania jako inhibitory furyny przeciwko wirusom z rodzaju Flavivirus i wirusom z rodziny Herpesviridae

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL449419A PL449419A1 (pl) 2024-07-31 2024-07-31 Cykliczne peptydy do zastosowania jako inhibitory furyny przeciwko wirusom z rodzaju Flavivirus i wirusom z rodziny Herpesviridae

Publications (1)

Publication Number Publication Date
PL449419A1 true PL449419A1 (pl) 2026-02-02

Family

ID=98604976

Family Applications (1)

Application Number Title Priority Date Filing Date
PL449419A PL449419A1 (pl) 2024-07-31 2024-07-31 Cykliczne peptydy do zastosowania jako inhibitory furyny przeciwko wirusom z rodzaju Flavivirus i wirusom z rodziny Herpesviridae

Country Status (1)

Country Link
PL (1) PL449419A1 (pl)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060142204A1 (en) * 2002-10-09 2006-06-29 Genoscience Pyrrolidine derivatives for use in treating heaptitis c virus infection
US20150141324A1 (en) * 2011-09-02 2015-05-21 SOCPRA Sciences Sante et Humaines S.E.C. Stable peptide-based furin inhibitors

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060142204A1 (en) * 2002-10-09 2006-06-29 Genoscience Pyrrolidine derivatives for use in treating heaptitis c virus infection
US20150141324A1 (en) * 2011-09-02 2015-05-21 SOCPRA Sciences Sante et Humaines S.E.C. Stable peptide-based furin inhibitors

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
GITLIN-DOMAGALSKA A. I INN.:: "ACS Medicinal Chemistry Letters 2023 14 (4), 458-465", CYCLIC PEPTIDIC FURIN INHIBITORS DEVELOPED BY COMBINATORIAL CHEMISTRY, *

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