PL447103A1 - Związki, pochodne 2-(1H)-chinolonu z ugrupowaniem benzotiazoliowym, sposób ich otrzymywania oraz ich zastosowanie - Google Patents

Związki, pochodne 2-(1H)-chinolonu z ugrupowaniem benzotiazoliowym, sposób ich otrzymywania oraz ich zastosowanie

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Publication number
PL447103A1
PL447103A1 PL447103A PL44710323A PL447103A1 PL 447103 A1 PL447103 A1 PL 447103A1 PL 447103 A PL447103 A PL 447103A PL 44710323 A PL44710323 A PL 44710323A PL 447103 A1 PL447103 A1 PL 447103A1
Authority
PL
Poland
Prior art keywords
derivative
quinolone
methylbenzo
formyl
iodide
Prior art date
Application number
PL447103A
Other languages
English (en)
Other versions
PL249639B1 (pl
Inventor
Jolanta Kolińska
Aleksandra Grzelakowska
Original Assignee
Politechnika Łódzka
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Politechnika Łódzka filed Critical Politechnika Łódzka
Priority to PL447103A priority Critical patent/PL249639B1/pl
Publication of PL447103A1 publication Critical patent/PL447103A1/pl
Publication of PL249639B1 publication Critical patent/PL249639B1/pl

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/29—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using visual detection
    • G01N21/293—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using visual detection with colour charts, graduated scales or turrets
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence

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  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Przedmiotem zgłoszenia są związki pochodne 2-(1H)-chinolonu z ugrupowaniem benzotiazoliowym w pozycji 3, o wzorze ogólnym I, w którym: R1, R2, oznaczają niezależnie od siebie atom wodoru, bromu, chloru, grupę metylową, metoksylową, N,N-dimetyloaminową lub N,N-dietyloaminową, R3 oznacza atom wodoru, grupę metylową, etylową lub propylową, a R4 oznacza grupę metylową, etylową lub propylową. Przedmiotem zgłoszenia jest także sposób otrzymywania związków o wzorze ogólnym I, w drodze kondensacji jodku pochodnej 2-metylobenzo[d]tiazolu z pochodną 3-formylo-2-(1H)-chinolonu, w środowisku bezwodnego etanolu, charakteryzujący się tym, że kondensacji poddaje się jodek pochodnej 2-metylobenzo[d]tiazolu o wzorze II z pochodną 3-formylo-2-(1H)-chinolonu o wzorze III, w których R1, R2, R3, R4 mają znaczenie określone w zastrzeżeniu 1, przy stosunku molowym pochodnej 3-formylo-2-(1H)-chinolonu do jodku pochodnej 2-metylobenzo[d]tiazolu 1:1, w środowisku bezwodnego etanolu użytego w ilości 295 — 590 moli na 1 mol jodku pochodnej 2-metylobenzo[d]tiazolu, w polu mikrofalowym o mocy zmiennej od 1 do 200 W, przy zakresie temperatury 80°C — 100°C w czasie 30 — 60 minut i po stwierdzeniu zaniku substratów w mieszaninie reakcyjnej za pomocą chromatografii cienkowarstwowej, w której fazę ruchomą stanowi mieszanina dichlorometanu i metanolu o stosunku objętościowym składników 10:1 (v/v), mieszaninę reakcyjną ochładza się do temperatury pokojowej, powstały osad produktu odsącza się, przemywa bezwodnym etanolem i suszy na powietrzu. Zgłoszenie obejmuje także zastosowanie związków o wzorze ogólnym I, jako znaczników kolorymetrycznych i fluorescencyjnych w detekcji anionu wodorosiarczynu.
PL447103A 2023-12-15 2023-12-15 Związki, pochodne 2-(1H)-chinolonu z ugrupowaniem benzotiazoliowym, sposób ich otrzymywania oraz ich zastosowanie PL249639B1 (pl)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL447103A PL249639B1 (pl) 2023-12-15 2023-12-15 Związki, pochodne 2-(1H)-chinolonu z ugrupowaniem benzotiazoliowym, sposób ich otrzymywania oraz ich zastosowanie

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL447103A PL249639B1 (pl) 2023-12-15 2023-12-15 Związki, pochodne 2-(1H)-chinolonu z ugrupowaniem benzotiazoliowym, sposób ich otrzymywania oraz ich zastosowanie

Publications (2)

Publication Number Publication Date
PL447103A1 true PL447103A1 (pl) 2025-06-16
PL249639B1 PL249639B1 (pl) 2026-05-25

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ID=96014235

Family Applications (1)

Application Number Title Priority Date Filing Date
PL447103A PL249639B1 (pl) 2023-12-15 2023-12-15 Związki, pochodne 2-(1H)-chinolonu z ugrupowaniem benzotiazoliowym, sposób ich otrzymywania oraz ich zastosowanie

Country Status (1)

Country Link
PL (1) PL249639B1 (pl)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2363459A1 (de) * 1973-12-20 1975-06-26 Basf Ag Neue fluoreszierende chinolinverbindungen
US20070281360A1 (en) * 2006-06-02 2007-12-06 Pierce Biotechnology, Inc. Protein detection and quantitation using hydroxyquinolone dyes

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2363459A1 (de) * 1973-12-20 1975-06-26 Basf Ag Neue fluoreszierende chinolinverbindungen
US20070281360A1 (en) * 2006-06-02 2007-12-06 Pierce Biotechnology, Inc. Protein detection and quantitation using hydroxyquinolone dyes

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
A., GRZELAKOWSKA ET AL.: "Coloration Technology 132 Issue 2, April 2016, 121-129; https://doi.org/10.1111/cote.12187", „SYNTHESIS, SPECTROSCOPIC CHARACTERISATION, AND POTENTIAL APPLICATION OF DYES CONTAINING A CARBOSTYRIL SKELETON AS SENSORS FOR THIOLS" *

Also Published As

Publication number Publication date
PL249639B1 (pl) 2026-05-25

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