PL446099A1 - Method for producing a bioactive coating from folic acid on the surface of porous implants, bioactive coating produced by this method and implant with bioactive coating - Google Patents
Method for producing a bioactive coating from folic acid on the surface of porous implants, bioactive coating produced by this method and implant with bioactive coatingInfo
- Publication number
- PL446099A1 PL446099A1 PL446099A PL44609923A PL446099A1 PL 446099 A1 PL446099 A1 PL 446099A1 PL 446099 A PL446099 A PL 446099A PL 44609923 A PL44609923 A PL 44609923A PL 446099 A1 PL446099 A1 PL 446099A1
- Authority
- PL
- Poland
- Prior art keywords
- bioactive coating
- implant
- folic acid
- producing
- coating
- Prior art date
Links
- 239000011248 coating agent Substances 0.000 title abstract 7
- 238000000576 coating method Methods 0.000 title abstract 7
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 title abstract 6
- 239000007943 implant Substances 0.000 title abstract 6
- 238000000034 method Methods 0.000 title abstract 5
- 230000000975 bioactive effect Effects 0.000 title abstract 4
- OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 title abstract 3
- 229960000304 folic acid Drugs 0.000 title abstract 3
- 235000019152 folic acid Nutrition 0.000 title abstract 3
- 239000011724 folic acid Substances 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title 1
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 abstract 2
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 210000000988 bone and bone Anatomy 0.000 abstract 1
- 238000007654 immersion Methods 0.000 abstract 1
- 230000008929 regeneration Effects 0.000 abstract 1
- 238000011069 regeneration method Methods 0.000 abstract 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 abstract 1
- 235000017557 sodium bicarbonate Nutrition 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Dermatology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Materials For Medical Uses (AREA)
Abstract
Przedmiotem zgłoszenia jest sposób wytwarzania bioaktywnej powłoki z kwasu foliowego na powierzchni porowatych implantów do regeneracji kości gąbczastej metodą zanurzeniową charakteryzujący się tym, że umieszcza się implant w roztworze powłokotwórczym, który stanowi wodny roztwór kwasu foliowego i wodorowęglanu sodu. Kolejnym przedmiotem zgłoszenia jest powłoka implantu wytworzona sposobem według wynalazku, jak również implant z powłoką wytworzoną sposobem według wynalazku.The subject of the application is a method of producing a bioactive coating of folic acid on the surface of porous implants for the regeneration of cancellous bone using the immersion method, characterized by placing the implant in a coating solution, which is an aqueous solution of folic acid and sodium bicarbonate. Another subject of the application is an implant coating produced by the method according to the invention, as well as an implant with a coating produced by the method according to the invention.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL446099A PL446099A1 (en) | 2023-09-14 | 2023-09-14 | Method for producing a bioactive coating from folic acid on the surface of porous implants, bioactive coating produced by this method and implant with bioactive coating |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL446099A PL446099A1 (en) | 2023-09-14 | 2023-09-14 | Method for producing a bioactive coating from folic acid on the surface of porous implants, bioactive coating produced by this method and implant with bioactive coating |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL446099A1 true PL446099A1 (en) | 2024-02-12 |
Family
ID=89855699
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL446099A PL446099A1 (en) | 2023-09-14 | 2023-09-14 | Method for producing a bioactive coating from folic acid on the surface of porous implants, bioactive coating produced by this method and implant with bioactive coating |
Country Status (1)
| Country | Link |
|---|---|
| PL (1) | PL446099A1 (en) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003099346A2 (en) * | 2002-05-24 | 2003-12-04 | Angiotech International Ag | Compositions and methods for coating medical implants |
| KR20050023270A (en) * | 2002-05-24 | 2005-03-09 | 안지오테크 인터내셔날 아게 | Compositions and methods for coating medical implants |
| US20130115263A1 (en) * | 2002-05-24 | 2013-05-09 | Angiotech Pharmaceuticals, Inc. | Compositions and methods for coating medical implants |
| CN109157674A (en) * | 2018-09-26 | 2019-01-08 | 湖北大学 | A kind of load medicine structure and preparation method thereof that surface of metal titanium pH controllably releases the drug |
-
2023
- 2023-09-14 PL PL446099A patent/PL446099A1/en unknown
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003099346A2 (en) * | 2002-05-24 | 2003-12-04 | Angiotech International Ag | Compositions and methods for coating medical implants |
| KR20050023270A (en) * | 2002-05-24 | 2005-03-09 | 안지오테크 인터내셔날 아게 | Compositions and methods for coating medical implants |
| US20130115263A1 (en) * | 2002-05-24 | 2013-05-09 | Angiotech Pharmaceuticals, Inc. | Compositions and methods for coating medical implants |
| CN109157674A (en) * | 2018-09-26 | 2019-01-08 | 湖北大学 | A kind of load medicine structure and preparation method thereof that surface of metal titanium pH controllably releases the drug |
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