PL445352A1 - Method of producing high purity acetamiprid and crystalline form of acetamiprid - Google Patents

Method of producing high purity acetamiprid and crystalline form of acetamiprid

Info

Publication number
PL445352A1
PL445352A1 PL445352A PL44535223A PL445352A1 PL 445352 A1 PL445352 A1 PL 445352A1 PL 445352 A PL445352 A PL 445352A PL 44535223 A PL44535223 A PL 44535223A PL 445352 A1 PL445352 A1 PL 445352A1
Authority
PL
Poland
Prior art keywords
acetamiprid
crystalline form
high purity
producing high
methyl
Prior art date
Application number
PL445352A
Other languages
Polish (pl)
Other versions
PL247425B1 (en
Inventor
Wiesław PUCKO
Andrzej Tarwacki
Arkadiusz Białek
Mirosław Gucma
Jarosław Hupko
Krzysztof Bajdor
Original Assignee
Sieć Badawcza Łukasiewicz - Instytut Przemysłu Organicznego
Instytut Chemii Organicznej Polskiej Akademii Nauk
Synthos Spółka Akcyjna
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sieć Badawcza Łukasiewicz - Instytut Przemysłu Organicznego, Instytut Chemii Organicznej Polskiej Akademii Nauk, Synthos Spółka Akcyjna filed Critical Sieć Badawcza Łukasiewicz - Instytut Przemysłu Organicznego
Priority to PL445352A priority Critical patent/PL247425B1/en
Publication of PL445352A1 publication Critical patent/PL445352A1/en
Publication of PL247425B1 publication Critical patent/PL247425B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61—Halogen atoms or nitro radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)

Abstract

Przedmiotem zgłoszenia jest sposób wytwarzania acetamiprydu w reakcji kondensacji N-metylo-2-chloro-5-pirydylometyloaminy i metylo- lub etylo- N-cyjanoacetamidyny. Reakcję kondensacji prowadzi się stosując w procesie jako rozpuszczalnik wodę lub mieszaninę woda-alkohol C1-C4 przy stosunku wagowym fazy wodnej do alkoholowej w zakresie od 10:1 do 1:10, w temperaturze pomiędzy 2°C a 40°C, a wydzielony produkt suszy się w temperaturze 40°C – 50°C. Wynalazek obejmuje także formę krystaliczną acetamiprydu.The subject of the application is a method for producing acetamiprid by condensation of N-methyl-2-chloro-5-pyridylmethylamine and methyl- or ethyl-N-cyanoacetamidine. The condensation reaction is carried out using water or a water-C1-C4 alcohol mixture as the solvent, at a weight ratio of the aqueous to alcohol phase in the range of 10:1 to 1:10, at a temperature between 2°C and 40°C, and the isolated product is dried at a temperature of 40°C - 50°C. The invention also includes a crystalline form of acetamiprid.

PL445352A 2023-06-23 2023-06-23 Method of producing high purity acetamiprid and crystalline form of acetamiprid PL247425B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL445352A PL247425B1 (en) 2023-06-23 2023-06-23 Method of producing high purity acetamiprid and crystalline form of acetamiprid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL445352A PL247425B1 (en) 2023-06-23 2023-06-23 Method of producing high purity acetamiprid and crystalline form of acetamiprid

Publications (2)

Publication Number Publication Date
PL445352A1 true PL445352A1 (en) 2024-12-30
PL247425B1 PL247425B1 (en) 2025-06-30

Family

ID=96171645

Family Applications (1)

Application Number Title Priority Date Filing Date
PL445352A PL247425B1 (en) 2023-06-23 2023-06-23 Method of producing high purity acetamiprid and crystalline form of acetamiprid

Country Status (1)

Country Link
PL (1) PL247425B1 (en)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102174013A (en) * 2011-03-10 2011-09-07 江苏长青农化股份有限公司 New synthesis technology of acetamiprid
CN106187868A (en) * 2016-07-15 2016-12-07 南通天泽化工有限公司 A kind of preparation method of Acetamiprid
CN107501172A (en) * 2017-09-03 2017-12-22 江苏长青农化股份有限公司 The production technology of Acetamiprid
CN111808018B (en) * 2020-08-14 2022-06-14 青岛恒宁生物科技有限公司 A kind of production technology of acetamiprid
CN114605319A (en) * 2020-12-09 2022-06-10 南通天泽化工有限公司 Preparation method of acetamiprid

Also Published As

Publication number Publication date
PL247425B1 (en) 2025-06-30

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