PL442547A1 - 4-Arylthiosemicarbazide derivatives for use in the treatment of toxoplasmosis - Google Patents

4-Arylthiosemicarbazide derivatives for use in the treatment of toxoplasmosis

Info

Publication number
PL442547A1
PL442547A1 PL442547A PL44254722A PL442547A1 PL 442547 A1 PL442547 A1 PL 442547A1 PL 442547 A PL442547 A PL 442547A PL 44254722 A PL44254722 A PL 44254722A PL 442547 A1 PL442547 A1 PL 442547A1
Authority
PL
Poland
Prior art keywords
arylthiosemicarbazide
toxoplasmosis
derivatives
treatment
syrup
Prior art date
Application number
PL442547A
Other languages
Polish (pl)
Inventor
Katarzyna Dzitko
Adrian Bekier
Justyna Gatkowska
Maciej Chyb
Original Assignee
Uniwersytet Łódzki
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uniwersytet Łódzki filed Critical Uniwersytet Łódzki
Priority to PL442547A priority Critical patent/PL442547A1/en
Publication of PL442547A1 publication Critical patent/PL442547A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • A61K31/175—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine having the group, >N—C(O)—N=N— or, e.g. carbonohydrazides, carbazones, semicarbazides, semicarbazones; Thioanalogues thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Przedmiotem zgłoszenia są pochodne 4-arylotiosemikarbazydu o wzorze 2a i 6a do zastosowania w leczeniu toksoplazmozy w postaci tabletek, proszku, granulek, kapsułek, syropu oraz roztworu do wstrzykiwania.The subject of the application are 4-arylthiosemicarbazide derivatives of formula 2a and 6a for use in the treatment of toxoplasmosis in the form of tablets, powder, granules, capsules, syrup and solution for injection.

PL442547A 2022-10-18 2022-10-18 4-Arylthiosemicarbazide derivatives for use in the treatment of toxoplasmosis PL442547A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL442547A PL442547A1 (en) 2022-10-18 2022-10-18 4-Arylthiosemicarbazide derivatives for use in the treatment of toxoplasmosis

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL442547A PL442547A1 (en) 2022-10-18 2022-10-18 4-Arylthiosemicarbazide derivatives for use in the treatment of toxoplasmosis

Publications (1)

Publication Number Publication Date
PL442547A1 true PL442547A1 (en) 2024-04-22

Family

ID=90790600

Family Applications (1)

Application Number Title Priority Date Filing Date
PL442547A PL442547A1 (en) 2022-10-18 2022-10-18 4-Arylthiosemicarbazide derivatives for use in the treatment of toxoplasmosis

Country Status (1)

Country Link
PL (1) PL442547A1 (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL426156A1 (en) * 2018-06-29 2020-01-02 Uniwersytet Medyczny W Lublinie 4-iodophenyl-1-(4-methylimidazol-5-yl)thiosemicarbazide derivatives, method of their preparation and medical use

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL426156A1 (en) * 2018-06-29 2020-01-02 Uniwersytet Medyczny W Lublinie 4-iodophenyl-1-(4-methylimidazol-5-yl)thiosemicarbazide derivatives, method of their preparation and medical use

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BEKIER A. I IN.: "J Enzyme Inhib Med Chem. 2021 Dec;36(1):1145-1164. doi: 10.1080/14756366.2021.1931164", "4-ARYLTHIOSEMICARBAZIDE DERIVATIVES AS A NEW CLASS OF TYROSINASE INHIBITORS AND ANTI-TOXOPLASMA GONDII AGENTS" *
PANETH A. I IN.: "Molecules. 2019 Apr 24;24(8):1618. doi: 10.3390/molecules24081618", "DISCOVERY OF POTENT AND SELECTIVE HALOGEN-SUBSTITUTED IMIDAZOLE-THIOSEMICARBAZIDES FOR INHIBITION OF TOXOPLASMA GONDII GROWTH IN VITRO VIA STRUCTURE-BASED DESIGN" *
PANETH A. I IN.: "Molecules. 2019 Feb 10;24(3):614. doi: 10.3390/molecules24030614", "SYSTEMATIC IDENTIFICATION OF THIOSEMICARBAZIDES FOR INHIBITION OF TOXOPLASMA GONDII GROWTH IN VITRO" *

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