PL438650A1 - Method for producing complexes of proteins with bacterial lipopolysaccharides, their use, a vaccine comprising an immunogenic LPS/protein complex and method for producing a vaccine - Google Patents

Method for producing complexes of proteins with bacterial lipopolysaccharides, their use, a vaccine comprising an immunogenic LPS/protein complex and method for producing a vaccine

Info

Publication number
PL438650A1
PL438650A1 PL438650A PL43865021A PL438650A1 PL 438650 A1 PL438650 A1 PL 438650A1 PL 438650 A PL438650 A PL 438650A PL 43865021 A PL43865021 A PL 43865021A PL 438650 A1 PL438650 A1 PL 438650A1
Authority
PL
Poland
Prior art keywords
vaccine
producing
lps
proteins
protein complex
Prior art date
Application number
PL438650A
Other languages
Polish (pl)
Inventor
Tomasz LIPIŃSKI
Jakub Siednienko
Original Assignee
Biovetika Spółka Z Ograniczoną Odpowiedzialnością
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biovetika Spółka Z Ograniczoną Odpowiedzialnością filed Critical Biovetika Spółka Z Ograniczoną Odpowiedzialnością
Priority to PL438650A priority Critical patent/PL438650A1/en
Priority to PCT/IB2022/057067 priority patent/WO2023007456A1/en
Publication of PL438650A1 publication Critical patent/PL438650A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/385—Haptens or antigens, bound to carriers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/025—Enterobacteriales, e.g. Enterobacter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/025—Enterobacteriales, e.g. Enterobacter
    • A61K39/0258—Escherichia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/025—Enterobacteriales, e.g. Enterobacter
    • A61K39/0275—Salmonella
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/105—Delta proteobacteriales, e.g. Lawsonia; Epsilon proteobacteriales, e.g. campylobacter, helicobacter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6081—Albumin; Keyhole limpet haemocyanin [KLH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6087—Polysaccharides; Lipopolysaccharides [LPS]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/62—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier
    • A61K2039/622—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier non-covalent binding
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/807—Hapten conjugated with peptide or protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Przedmiotem wynalazku jest sposób wytwarzania kompleksów immunologicznych lipopolisacharyd bakteryjny (LPS)/białko, zastosowanie kompleksu LPS/białko do indukcji odpowiedzi immunologicznej, sposób wytwarzania szczepionki weterynaryjnej zawierającej kompleks immunologiczny LPS/białko oraz szczepionka weterynaryjna wytwarzana tym sposobem.The present invention relates to a method for producing bacterial lipopolysaccharide (LPS)/protein immune complexes, the use of an LPS/protein complex for inducing an immune response, a method for producing a veterinary vaccine comprising an LPS/protein immune complex, and a veterinary vaccine produced by the method.

PL438650A 2021-07-30 2021-07-30 Method for producing complexes of proteins with bacterial lipopolysaccharides, their use, a vaccine comprising an immunogenic LPS/protein complex and method for producing a vaccine PL438650A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
PL438650A PL438650A1 (en) 2021-07-30 2021-07-30 Method for producing complexes of proteins with bacterial lipopolysaccharides, their use, a vaccine comprising an immunogenic LPS/protein complex and method for producing a vaccine
PCT/IB2022/057067 WO2023007456A1 (en) 2021-07-30 2022-07-29 A method for producing complexes of proteins with bacterial lipopolysaccharides, the use thereof, a vaccine comprising an lps/protein immunogenic complex and a method for producing the vaccine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL438650A PL438650A1 (en) 2021-07-30 2021-07-30 Method for producing complexes of proteins with bacterial lipopolysaccharides, their use, a vaccine comprising an immunogenic LPS/protein complex and method for producing a vaccine

Publications (1)

Publication Number Publication Date
PL438650A1 true PL438650A1 (en) 2023-02-06

Family

ID=83598567

Family Applications (1)

Application Number Title Priority Date Filing Date
PL438650A PL438650A1 (en) 2021-07-30 2021-07-30 Method for producing complexes of proteins with bacterial lipopolysaccharides, their use, a vaccine comprising an immunogenic LPS/protein complex and method for producing a vaccine

Country Status (2)

Country Link
PL (1) PL438650A1 (en)
WO (1) WO2023007456A1 (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL217758B1 (en) * 2008-09-29 2014-08-29 Inst Immunologii I Terapii Doświadczalnej Pan Method of bonding bacterial lipopolysaccharides into the solid phase

Also Published As

Publication number Publication date
WO2023007456A1 (en) 2023-02-02

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