PL4377323T3 - Wytwarzanie dimerycznych środków kontrastowych - Google Patents

Wytwarzanie dimerycznych środków kontrastowych

Info

Publication number
PL4377323T3
PL4377323T3 PL22754878.1T PL22754878T PL4377323T3 PL 4377323 T3 PL4377323 T3 PL 4377323T3 PL 22754878 T PL22754878 T PL 22754878T PL 4377323 T3 PL4377323 T3 PL 4377323T3
Authority
PL
Poland
Prior art keywords
manufacturing
contrast agents
dimeric contrast
dimeric
agents
Prior art date
Application number
PL22754878.1T
Other languages
English (en)
Inventor
Andrea BANIN
Andrea BARALE
Valeria BOI
Sonia Gazzetto
Federica Buonsanti
Original Assignee
Bracco Imaging Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco Imaging Spa filed Critical Bracco Imaging Spa
Publication of PL4377323T3 publication Critical patent/PL4377323T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/003Compounds containing elements of Groups 3 or 13 of the Periodic Table without C-Metal linkages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10Organic compounds
    • A61K49/101Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
    • A61K49/106Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being cyclic, e.g. DOTA
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D257/00Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10Organic compounds
    • A61K49/12Macromolecular compounds
    • A61K49/122Macromolecular compounds dimers of complexes or complex-forming compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Radiology & Medical Imaging (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
PL22754878.1T 2021-07-27 2022-07-26 Wytwarzanie dimerycznych środków kontrastowych PL4377323T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP21187883 2021-07-27
PCT/EP2022/070901 WO2023006721A1 (en) 2021-07-27 2022-07-26 Manufacturing of dimeric contrast agents

Publications (1)

Publication Number Publication Date
PL4377323T3 true PL4377323T3 (pl) 2025-12-01

Family

ID=77367218

Family Applications (1)

Application Number Title Priority Date Filing Date
PL22754878.1T PL4377323T3 (pl) 2021-07-27 2022-07-26 Wytwarzanie dimerycznych środków kontrastowych

Country Status (13)

Country Link
US (1) US12290576B2 (pl)
EP (1) EP4377323B1 (pl)
JP (1) JP7774081B2 (pl)
KR (1) KR20240034693A (pl)
CN (1) CN117412980A (pl)
AU (1) AU2022317221A1 (pl)
BR (1) BR112023022921A2 (pl)
CA (1) CA3216972A1 (pl)
ES (1) ES3041651T3 (pl)
IL (1) IL308888A (pl)
MX (1) MX2023014582A (pl)
PL (1) PL4377323T3 (pl)
WO (1) WO2023006721A1 (pl)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4009119A1 (de) * 1990-03-19 1991-09-26 Schering Ag 1,4,7,10-tetraazacyclododecan-butyltriole, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel
DE4035760A1 (de) * 1990-11-08 1992-05-14 Schering Ag Mono-n-substituierte 1,4,7,10-tetraazacyclododecan-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel
IT1291624B1 (it) * 1997-04-18 1999-01-11 Bracco Spa Chelati complessi di metalli paramagnetici a bassa tossicita'
DE19849465A1 (de) * 1998-10-21 2000-04-27 Schering Ag Dimere Ionenpaare, Verfahren zu ihrer Herstellung und ihre Verwendung als Kontrastmittel
IT1304501B1 (it) * 1998-12-23 2001-03-19 Bracco Spa Uso di derivati di acidi biliari coniugati con complessi metallicicome "blood pool agents" per l'indagine diagnostica tramite risonanza
DK3386954T3 (da) * 2015-12-10 2021-02-15 Bracco Imaging Spa Dimere kontrastmidler
CN114845998B (zh) * 2019-12-13 2024-06-25 伯拉考成像股份公司 受保护的do3a的制备

Also Published As

Publication number Publication date
BR112023022921A2 (pt) 2024-02-27
WO2023006721A1 (en) 2023-02-02
AU2022317221A1 (en) 2023-11-16
US12290576B2 (en) 2025-05-06
US20240269330A1 (en) 2024-08-15
JP2024527691A (ja) 2024-07-26
EP4377323A1 (en) 2024-06-05
JP7774081B2 (ja) 2025-11-20
CN117412980A (zh) 2024-01-16
KR20240034693A (ko) 2024-03-14
EP4377323C0 (en) 2025-07-02
IL308888A (en) 2024-01-01
EP4377323B1 (en) 2025-07-02
CA3216972A1 (en) 2023-02-02
ES3041651T3 (en) 2025-11-13
MX2023014582A (es) 2023-12-13

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