PL437113A1 - Artificial TRAP cage, its use and method of its preparation - Google Patents

Artificial TRAP cage, its use and method of its preparation

Info

Publication number
PL437113A1
PL437113A1 PL437113A PL43711321A PL437113A1 PL 437113 A1 PL437113 A1 PL 437113A1 PL 437113 A PL437113 A PL 437113A PL 43711321 A PL43711321 A PL 43711321A PL 437113 A1 PL437113 A1 PL 437113A1
Authority
PL
Poland
Prior art keywords
preparation
cage
artificial
trap cage
linkers
Prior art date
Application number
PL437113A
Other languages
Polish (pl)
Inventor
Jonathan Heddle
Artur BIELA
Yusuke Azuma
Izabela STUPKA
Karolina MAJSTERKIEWICZ
Original Assignee
Uniwersytet Jagielloński
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uniwersytet Jagielloński filed Critical Uniwersytet Jagielloński
Priority to PL437113A priority Critical patent/PL437113A1/en
Priority to US18/547,256 priority patent/US20240122868A1/en
Priority to CA3209417A priority patent/CA3209417A1/en
Priority to JP2023551178A priority patent/JP2024507379A/en
Priority to CA3209414A priority patent/CA3209414A1/en
Priority to US18/547,274 priority patent/US20240139339A1/en
Priority to EP22710454.4A priority patent/EP4298117A1/en
Priority to PCT/PL2022/050010 priority patent/WO2022182261A1/en
Priority to JP2023551176A priority patent/JP2024507900A/en
Priority to CA3209412A priority patent/CA3209412A1/en
Priority to EP22710452.8A priority patent/EP4298115A1/en
Priority to EP22710453.6A priority patent/EP4298116A1/en
Priority to JP2023551177A priority patent/JP2024507901A/en
Priority to PCT/PL2022/050011 priority patent/WO2022182262A1/en
Priority to PCT/PL2022/050009 priority patent/WO2022182260A1/en
Publication of PL437113A1 publication Critical patent/PL437113A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Inorganic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)

Abstract

Przedmiotem niniejszego wynalazku jest sztuczna klatka TRAP obejmująca wybraną liczbę pierścieni TRAP, które są utrzymywane na miejscu przez molekularne łączniki sieciujące, przy czym łączniki sieciujące wybiera się ze względu na ich specyficzne właściwości, a klatki można zaprogramować tak, aby otwierały się lub pozostawały zamknięte na żądanie, w określonych warunkach. Przedmiotem zgłoszenia jest także zastosowanie powyższej klatki oraz sposób jej przygotowania.The present invention relates to an artificial TRAP cage comprising a selected number of TRAP rings that are held in place by molecular cross-linkers, the cross-linkers selected for their specific properties, and the cages can be programmed to open or remain closed on demand. , under certain conditions. The subject of the notification is also the use of the above cage and the method of its preparation.

PL437113A 2021-02-24 2021-02-24 Artificial TRAP cage, its use and method of its preparation PL437113A1 (en)

Priority Applications (15)

Application Number Priority Date Filing Date Title
PL437113A PL437113A1 (en) 2021-02-24 2021-02-24 Artificial TRAP cage, its use and method of its preparation
US18/547,256 US20240122868A1 (en) 2021-02-24 2022-02-24 An artificial trap-cage, its use and method of preparing thereof
CA3209417A CA3209417A1 (en) 2021-02-24 2022-02-24 An artificial protein-cage comprising encapsulated therein a guest cargo
JP2023551178A JP2024507379A (en) 2021-02-24 2022-02-24 Artificial TRAP cage, its use, and method of its preparation
CA3209414A CA3209414A1 (en) 2021-02-24 2022-02-24 An artificial trap-cage, its use and method of preparing thereof
US18/547,274 US20240139339A1 (en) 2021-02-24 2022-02-24 An artificial protein-cage decorated with particular molecules on the exterior
EP22710454.4A EP4298117A1 (en) 2021-02-24 2022-02-24 An artificial protein-cage comprising encapsulated therein a guest cargo
PCT/PL2022/050010 WO2022182261A1 (en) 2021-02-24 2022-02-24 An artificial trap-cage, its use and method of preparing thereof
JP2023551176A JP2024507900A (en) 2021-02-24 2022-02-24 Artificial protein cage decorated with specific molecules on the outside
CA3209412A CA3209412A1 (en) 2021-02-24 2022-02-24 An artificial protein-cage decorated with particular molecules on the exterior
EP22710452.8A EP4298115A1 (en) 2021-02-24 2022-02-24 An artificial protein-cage decorated with particular molecules on the exterior
EP22710453.6A EP4298116A1 (en) 2021-02-24 2022-02-24 An artificial trap-cage, its use and method of preparing thereof
JP2023551177A JP2024507901A (en) 2021-02-24 2022-02-24 Artificial protein cage containing guest cargo encapsulated within it
PCT/PL2022/050011 WO2022182262A1 (en) 2021-02-24 2022-02-24 An artificial protein-cage comprising encapsulated therein a guest cargo
PCT/PL2022/050009 WO2022182260A1 (en) 2021-02-24 2022-02-24 An artificial protein-cage decorated with particular molecules on the exterior

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL437113A PL437113A1 (en) 2021-02-24 2021-02-24 Artificial TRAP cage, its use and method of its preparation

Publications (1)

Publication Number Publication Date
PL437113A1 true PL437113A1 (en) 2022-08-29

Family

ID=83723961

Family Applications (1)

Application Number Title Priority Date Filing Date
PL437113A PL437113A1 (en) 2021-02-24 2021-02-24 Artificial TRAP cage, its use and method of its preparation

Country Status (1)

Country Link
PL (1) PL437113A1 (en)

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