PL427326A1 - Radiosensybilizator w postaci 5-jodo-4-tio-2'-deoksyurydyny do zastosowania w radioterapii <!--[if gte mso 9]><xml> <o:OfficeDocumentSettings> <o:RelyOnVML/> <o:AllowPNG/> </o:OfficeDocumentSettings> </xml><![endif]--> - Google Patents
Radiosensybilizator w postaci 5-jodo-4-tio-2'-deoksyurydyny do zastosowania w radioterapii <!--[if gte mso 9]><xml> <o:OfficeDocumentSettings> <o:RelyOnVML/> <o:AllowPNG/> </o:OfficeDocumentSettings> </xml><![endif]-->Info
- Publication number
- PL427326A1 PL427326A1 PL427326A PL42732618A PL427326A1 PL 427326 A1 PL427326 A1 PL 427326A1 PL 427326 A PL427326 A PL 427326A PL 42732618 A PL42732618 A PL 42732618A PL 427326 A1 PL427326 A1 PL 427326A1
- Authority
- PL
- Poland
- Prior art keywords
- radiosensitizer
- deoxyuridine
- radiotherapy
- iodo
- thio
- Prior art date
Links
- BNLCCMFWEQHLJL-RRKCRQDMSA-N 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodo-4-sulfanylidenepyrimidin-2-one Chemical compound OC[C@H]1O[C@H](C[C@@H]1O)n1cc(I)c(=S)[nH]c1=O BNLCCMFWEQHLJL-RRKCRQDMSA-N 0.000 title abstract 2
- 239000002534 radiation-sensitizing agent Substances 0.000 title abstract 2
- 238000001959 radiotherapy Methods 0.000 title abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 230000005855 radiation Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0038—Radiosensitizing, i.e. administration of pharmaceutical agents that enhance the effect of radiotherapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Przedmiotem zgłoszenia jest 5-jodo-4-tio-2'-deoksyurydyna do zastosowania w radioterapii jako radiosensybilizator, zwiększający efektywność działania promieniowania wobec komórek nowotworowych.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL427326A PL236657B1 (pl) | 2018-10-02 | 2018-10-02 | Radiosensybilizator do zastosowania w radioterapii |
| EP19200633.6A EP3632468B1 (en) | 2018-10-02 | 2019-09-30 | 5-iodo-4-thio-2'-deoxyuridine for use as a radiosensitizer in radiotherapy |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL427326A PL236657B1 (pl) | 2018-10-02 | 2018-10-02 | Radiosensybilizator do zastosowania w radioterapii |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL427326A1 true PL427326A1 (pl) | 2020-04-06 |
| PL236657B1 PL236657B1 (pl) | 2021-02-08 |
Family
ID=68502794
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL427326A PL236657B1 (pl) | 2018-10-02 | 2018-10-02 | Radiosensybilizator do zastosowania w radioterapii |
Country Status (2)
| Country | Link |
|---|---|
| EP (1) | EP3632468B1 (pl) |
| PL (1) | PL236657B1 (pl) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL448242A1 (pl) * | 2024-04-09 | 2025-10-13 | Uniwersytet Gdański | Pochodna 2'-deoksyadenozyny w postaci 8-benzylo(4-trifluorometoksy)-2'-deoksyadenozyny, sposób jej otrzymywania oraz jej zastosowanie jako radiosensybilizator |
-
2018
- 2018-10-02 PL PL427326A patent/PL236657B1/pl unknown
-
2019
- 2019-09-30 EP EP19200633.6A patent/EP3632468B1/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| PL236657B1 (pl) | 2021-02-08 |
| EP3632468B1 (en) | 2023-12-13 |
| EP3632468A1 (en) | 2020-04-08 |
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