PL424245A1 - Method for obtaining 7-methoxy-1,2,3-tris(4-methoxyphenyl)-1,2,3,4-tetrahydronaphthalene - Google Patents
Method for obtaining 7-methoxy-1,2,3-tris(4-methoxyphenyl)-1,2,3,4-tetrahydronaphthaleneInfo
- Publication number
- PL424245A1 PL424245A1 PL424245A PL42424518A PL424245A1 PL 424245 A1 PL424245 A1 PL 424245A1 PL 424245 A PL424245 A PL 424245A PL 42424518 A PL42424518 A PL 42424518A PL 424245 A1 PL424245 A1 PL 424245A1
- Authority
- PL
- Poland
- Prior art keywords
- tetrahydronaphthalene
- methoxyphenyl
- tris
- methoxy
- obtaining
- Prior art date
Links
Abstract
Przedmiotem zgłoszenia jest sposób otrzymywania 7-metoksy-1,2,3-tris(4-metoksyfenylo)-1,2,3,4-tetrahydronaftalenu o wzorze 1. Sposób ten polega na tym, że (E)-4,4'-dimetoksystilben rozpuszcza się w chlorku metylenu, dodaje się jod 1-1 mol/mol w stosunku do stilbenu i miesza przez co najmniej 20 godzin w temperaturze 20 - 30°C, następnie do mieszaniny reakcyjnej dodaje się wodę i poddaje kilkakrotnie ekstrakcji a połączone fazy organiczne przemywa się wodnym roztworem pirosiarczynu sodu, a następnie wodą po czym warstwę organiczną suszy się bezwodnym MgSO4 i zatęża.The subject of the application is a method for obtaining 7-methoxy-1,2,3-tris (4-methoxyphenyl) -1,2,3,4-tetrahydronaphthalene of formula 1. This method consists in the fact that (E) -4,4 ' -dimethoxystilbene is dissolved in methylene chloride, iodine 1-1 mol / mol is added to stilbene and stirred for at least 20 hours at 20-30 ° C, then water is added to the reaction mixture and extracted several times and the combined phases the organic was washed with aqueous sodium metabisulfite and then with water, and the organic layer was dried over anhydrous MgSO 4 and concentrated.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PL424245A PL233977B1 (en) | 2018-01-10 | 2018-01-10 | Method for obtaining 7-methoxy-1,2,3-tris(4-methoxyphenyl)-1,2,3,4-tetrahydronaphthalene |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PL424245A PL233977B1 (en) | 2018-01-10 | 2018-01-10 | Method for obtaining 7-methoxy-1,2,3-tris(4-methoxyphenyl)-1,2,3,4-tetrahydronaphthalene |
Publications (2)
Publication Number | Publication Date |
---|---|
PL424245A1 true PL424245A1 (en) | 2019-07-15 |
PL233977B1 PL233977B1 (en) | 2019-12-31 |
Family
ID=67209664
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL424245A PL233977B1 (en) | 2018-01-10 | 2018-01-10 | Method for obtaining 7-methoxy-1,2,3-tris(4-methoxyphenyl)-1,2,3,4-tetrahydronaphthalene |
Country Status (1)
Country | Link |
---|---|
PL (1) | PL233977B1 (en) |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1670458A1 (en) * | 2003-10-08 | 2006-06-21 | Schering Aktiengesellschaft | 1-amino-2-oxy-substituted tetrahydronaphtalene derivatives, methods for the production thereof, and their use as antiphlogistics |
KR20080053895A (en) * | 2006-12-11 | 2008-06-16 | 메르크 파텐트 게엠베하 | Stilbene derivatives, liquid-crystal mixtures and electro-optical displays |
EP1994005A1 (en) * | 2006-03-15 | 2008-11-26 | Bayer Schering Pharma Aktiengesellschaft | Tetrahydronaphthaline derivatives, methods for the production and use thereof as anti-inflammatory agents |
-
2018
- 2018-01-10 PL PL424245A patent/PL233977B1/en unknown
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1670458A1 (en) * | 2003-10-08 | 2006-06-21 | Schering Aktiengesellschaft | 1-amino-2-oxy-substituted tetrahydronaphtalene derivatives, methods for the production thereof, and their use as antiphlogistics |
EP1994005A1 (en) * | 2006-03-15 | 2008-11-26 | Bayer Schering Pharma Aktiengesellschaft | Tetrahydronaphthaline derivatives, methods for the production and use thereof as anti-inflammatory agents |
KR20080053895A (en) * | 2006-12-11 | 2008-06-16 | 메르크 파텐트 게엠베하 | Stilbene derivatives, liquid-crystal mixtures and electro-optical displays |
Also Published As
Publication number | Publication date |
---|---|
PL233977B1 (en) | 2019-12-31 |
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