PL423711A1 - Method for obtaining degradable hydrogels based on derivatives of trehalose and their applications - Google Patents
Method for obtaining degradable hydrogels based on derivatives of trehalose and their applicationsInfo
- Publication number
- PL423711A1 PL423711A1 PL423711A PL42371117A PL423711A1 PL 423711 A1 PL423711 A1 PL 423711A1 PL 423711 A PL423711 A PL 423711A PL 42371117 A PL42371117 A PL 42371117A PL 423711 A1 PL423711 A1 PL 423711A1
- Authority
- PL
- Poland
- Prior art keywords
- trehalose
- derivatives
- applications
- hydrogels
- obtaining
- Prior art date
Links
Abstract
Przedmiotem zgłoszenia jest sposób otrzymywania hydrożeli o zróżnicowanej degradowalności, mających zastosowanie jako nośniki związków biologicznie aktywnych, który polega na tym, że do syntezy hydrożeli wykorzystano czynniki sieciujące będące diacetalowymi, benzylidenowymi pochodnymi trehalozy z wielokrotnymi (n=1-25) ugrupowaniami, etoksylowymi lub propyloksylowymi zakończonymi grupami (met)akrylowymi. Przedmiotem zgłoszenia jest także zastosowanie hydrożeli jako degradowalnych nośników związków biologicznie aktywnych, w szczególności białek, peptydów, oligonukleotydów w roztworach o pH 3,5 - 7,0.The subject of the application is a method of obtaining hydrogels of various degradability, which are used as carriers of biologically active compounds, which consists in the fact that for the synthesis of hydrogels cross-linking agents were used which are diacetal, benzylidene trehalose derivatives with multiple (n = 1-25) ethoxy or propyloxy moieties completed (meth) acrylic groups. The subject of the application is also the use of hydrogels as degradable carriers of biologically active compounds, in particular proteins, peptides, oligonucleotides in solutions with a pH of 3.5 - 7.0.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PL423711A PL236444B1 (en) | 2017-12-04 | 2017-12-04 | Method for obtaining degradable hydrogels based on derivatives of trehalose and their applications |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PL423711A PL236444B1 (en) | 2017-12-04 | 2017-12-04 | Method for obtaining degradable hydrogels based on derivatives of trehalose and their applications |
Publications (2)
Publication Number | Publication Date |
---|---|
PL423711A1 true PL423711A1 (en) | 2019-06-17 |
PL236444B1 PL236444B1 (en) | 2021-01-11 |
Family
ID=66809672
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL423711A PL236444B1 (en) | 2017-12-04 | 2017-12-04 | Method for obtaining degradable hydrogels based on derivatives of trehalose and their applications |
Country Status (1)
Country | Link |
---|---|
PL (1) | PL236444B1 (en) |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1994014523A1 (en) * | 1992-12-24 | 1994-07-07 | Ferngas Salzgitter Gmbh | Method of treating contaminated media in dust form |
US5474915A (en) * | 1990-05-08 | 1995-12-12 | University Of Iowa Research Foundation | Method of making poly(sugar acrylates) using hydrolytic enzymes |
PL338859A1 (en) * | 1997-08-20 | 2000-11-20 | Rhone Poulenc Agrochimie | Androctonin coding gene, vector containing same and transformed plants immune to a disease obtained by using them |
WO2016025551A1 (en) * | 2014-08-12 | 2016-02-18 | The Regents Of The University Of California | Trehalose hydrogels for stabilization and delivery of proteins |
-
2017
- 2017-12-04 PL PL423711A patent/PL236444B1/en unknown
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5474915A (en) * | 1990-05-08 | 1995-12-12 | University Of Iowa Research Foundation | Method of making poly(sugar acrylates) using hydrolytic enzymes |
WO1994014523A1 (en) * | 1992-12-24 | 1994-07-07 | Ferngas Salzgitter Gmbh | Method of treating contaminated media in dust form |
PL338859A1 (en) * | 1997-08-20 | 2000-11-20 | Rhone Poulenc Agrochimie | Androctonin coding gene, vector containing same and transformed plants immune to a disease obtained by using them |
WO2016025551A1 (en) * | 2014-08-12 | 2016-02-18 | The Regents Of The University Of California | Trehalose hydrogels for stabilization and delivery of proteins |
Also Published As
Publication number | Publication date |
---|---|
PL236444B1 (en) | 2021-01-11 |
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