PL419802A1 - [(1R,4R,6S)-3-Ethenyl-4,7,7-trimethylbicyclo[4.1.0]hept-3-ylo]acetate ethyl and method for producing it - Google Patents

[(1R,4R,6S)-3-Ethenyl-4,7,7-trimethylbicyclo[4.1.0]hept-3-ylo]acetate ethyl and method for producing it

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Publication number
PL419802A1
PL419802A1 PL419802A PL41980216A PL419802A1 PL 419802 A1 PL419802 A1 PL 419802A1 PL 419802 A PL419802 A PL 419802A PL 41980216 A PL41980216 A PL 41980216A PL 419802 A1 PL419802 A1 PL 419802A1
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PL
Poland
Prior art keywords
hept
trimethylbicyclo
ethenyl
producing
ylo
Prior art date
Application number
PL419802A
Other languages
Polish (pl)
Other versions
PL230279B1 (en
Inventor
Stanisław Lochyński
Agata Kozioł
Jakub Frątczak
Original Assignee
Politechnika Wrocławska
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Politechnika Wrocławska filed Critical Politechnika Wrocławska
Priority to PL419802A priority Critical patent/PL230279B1/en
Publication of PL419802A1 publication Critical patent/PL419802A1/en
Publication of PL230279B1 publication Critical patent/PL230279B1/en

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Abstract

Zgłoszenie dotyczy [(1R,4R,6S)-3-etenylo-4,7,7-trimetylobicyklo[4.1.0]hept-3-ylo]octanem etylu, o wzorze 1. Zgłoszenie zawiera też sposób wytwarzania [(1R,4R,6S)-3-etenylo-4,7,7-trimetylobicyklo[4.1.0]hept-3-ylo]octanu etylu o wzorze 1 znamienny tym, (2E)-2-[(1R,4R,6S)-4,7,7-trimetylobicyklo[4.1.0]hept-3-ylideno]etanol poddaje się reakcji przegrupowania Claisena, przy czym reakcję prowadzi się w koszu grzejnym w temperaturze 137°C, a przebieg reakcji kontroluje się za pomocą chromatografii cienkowarstwowej, a po zakończeniu procesu oddestylowuje się nadmiar ortooctanu etylu, a produkt oczyszcza się za pomocą chromatografii kolumnowej.The application relates to [(1R, 4R, 6S) -3-ethenyl-4,7,7-trimethyl-bicyclo [4.1.0] hept-3-yl] with ethyl acetate, of formula 1. The application also contains a method for producing [(1R, 4R , 6S) -3-ethenyl-4,7,7-trimethylbicyclo [4.1.0] hept-3-yl] acetate of formula 1 characterized by (2E) -2 - [(1R, 4R, 6S) -4 , 7,7-trimethylbicyclo [4.1.0] hept-3-ylidene] ethanol is subjected to a Claisen rearrangement reaction, the reaction is carried out in a heating basket at 137 ° C, and the course of the reaction is controlled by thin layer chromatography, and then at the end of the process, excess ethyl orthoacetate is distilled off and the product is purified by column chromatography.

PL419802A 2016-12-14 2016-12-14 [(1R,4R,6S)-3-Ethenyl-4,7,7-trimethylbicyclo[4.1.0]hept-3-ylo]acetate ethyl and method for producing it PL230279B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL419802A PL230279B1 (en) 2016-12-14 2016-12-14 [(1R,4R,6S)-3-Ethenyl-4,7,7-trimethylbicyclo[4.1.0]hept-3-ylo]acetate ethyl and method for producing it

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL419802A PL230279B1 (en) 2016-12-14 2016-12-14 [(1R,4R,6S)-3-Ethenyl-4,7,7-trimethylbicyclo[4.1.0]hept-3-ylo]acetate ethyl and method for producing it

Publications (2)

Publication Number Publication Date
PL419802A1 true PL419802A1 (en) 2018-01-03
PL230279B1 PL230279B1 (en) 2018-10-31

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Family Applications (1)

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PL419802A PL230279B1 (en) 2016-12-14 2016-12-14 [(1R,4R,6S)-3-Ethenyl-4,7,7-trimethylbicyclo[4.1.0]hept-3-ylo]acetate ethyl and method for producing it

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Publication number Publication date
PL230279B1 (en) 2018-10-31

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