PL411215A1 - Method for producing bimetallic silver-copper nanoparticles modified by polyphenols and their application as antiviral preparation - Google Patents

Method for producing bimetallic silver-copper nanoparticles modified by polyphenols and their application as antiviral preparation

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Publication number
PL411215A1
PL411215A1 PL411215A PL41121515A PL411215A1 PL 411215 A1 PL411215 A1 PL 411215A1 PL 411215 A PL411215 A PL 411215A PL 41121515 A PL41121515 A PL 41121515A PL 411215 A1 PL411215 A1 PL 411215A1
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PL
Poland
Prior art keywords
polyphenols
silver
copper
metal ions
application
Prior art date
Application number
PL411215A
Other languages
Polish (pl)
Other versions
PL234349B1 (en
Inventor
Jarosław Grobelny
Grzegorz Celichowski
Emilia Tomaszewska
Katarzyna Soliwoda
Małgorzata Krzyżowska
Piotr Orłowski
Original Assignee
Uniwersytet Łódzki
Wojskowy Instytut Higieny I Epidemiologii
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Uniwersytet Łódzki, Wojskowy Instytut Higieny I Epidemiologii filed Critical Uniwersytet Łódzki
Priority to PL411215A priority Critical patent/PL234349B1/en
Publication of PL411215A1 publication Critical patent/PL411215A1/en
Publication of PL234349B1 publication Critical patent/PL234349B1/en

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Abstract

Przedmiotem wynalazku jest sposób wytwarzania nanocząstek bimetalicznych srebrowo - miedziowych modyfikowanych polifenolami i ich zastosowanie w terapii przeciwwirusowej. Sposób polega na tym, że do wodnego roztworu soli srebra i miedzi o sumarycznym stężeniu jonów metalu wynoszącym od 10 do 200 ppm o temperaturze 60 - 100°C dodaje się wodny roztwór mieszaniny polifenoli i cytrynianu sodu, które pełnią odpowiednio rolę reduktorów i stabilizatorów powstających nanocząstek. W mieszaninie reakcyjnej nadmiar molowy cytrynianu sodu wynosi od 0,5 do 11 w przeliczeniu na łączną liczbę jonów metali, a nadmiar molowy polifenoli wynosi od 2 do 7 w przeliczeniu na łączną liczbę jonów metali. Opis obejmuje syntezy, w których zawartość miedzi w stosunku do srebra wynosi od 5 do 50% masowych. Ujawniono także zastosowanie nanocząstek srebrowo - miedziowych jako preparatu przeciwwirusowego.The subject of the invention is a method of producing silver-copper bimetallic nanoparticles modified with polyphenols and their use in antiviral therapy. The method consists in adding to the aqueous solution of silver and copper salts with a total concentration of metal ions ranging from 10 to 200 ppm at a temperature of 60 - 100 ° C, an aqueous solution of a mixture of polyphenols and sodium citrate, which act as reducing agents and stabilizers of the formed nanoparticles, respectively, is added. . In the reaction mixture, the molar excess of sodium citrate is from 0.5 to 11 based on the total number of metal ions, and the molar excess of polyphenols is from 2 to 7 calculated on the total number of metal ions. The description includes syntheses in which the copper content with respect to silver is between 5 and 50% by mass. The use of silver-copper nanoparticles as an antiviral preparation has also been disclosed.

PL411215A 2015-02-09 2015-02-09 Method for producing bimetallic silver-copper nanoparticles modified by polyphenols and their application as antiviral preparation PL234349B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL411215A PL234349B1 (en) 2015-02-09 2015-02-09 Method for producing bimetallic silver-copper nanoparticles modified by polyphenols and their application as antiviral preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL411215A PL234349B1 (en) 2015-02-09 2015-02-09 Method for producing bimetallic silver-copper nanoparticles modified by polyphenols and their application as antiviral preparation

Publications (2)

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PL411215A1 true PL411215A1 (en) 2016-08-16
PL234349B1 PL234349B1 (en) 2020-02-28

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Family Applications (1)

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PL411215A PL234349B1 (en) 2015-02-09 2015-02-09 Method for producing bimetallic silver-copper nanoparticles modified by polyphenols and their application as antiviral preparation

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PL (1) PL234349B1 (en)

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PL234349B1 (en) 2020-02-28

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