PL4097091T3 - Postacie stałe mawakamtenu i sposób ich wytwarzania - Google Patents
Postacie stałe mawakamtenu i sposób ich wytwarzaniaInfo
- Publication number
- PL4097091T3 PL4097091T3 PL21706793.3T PL21706793T PL4097091T3 PL 4097091 T3 PL4097091 T3 PL 4097091T3 PL 21706793 T PL21706793 T PL 21706793T PL 4097091 T3 PL4097091 T3 PL 4097091T3
- Authority
- PL
- Poland
- Prior art keywords
- mavacamten
- preparation
- solid state
- state forms
- forms
- Prior art date
Links
- RLCLASQCAPXVLM-NSHDSACASA-N CC(C)n1c(=O)cc(N[C@@H](C)c2ccccc2)[nH]c1=O Chemical compound CC(C)n1c(=O)cc(N[C@@H](C)c2ccccc2)[nH]c1=O RLCLASQCAPXVLM-NSHDSACASA-N 0.000 title 1
- 229940069673 mavacamten Drugs 0.000 title 1
- 239000007787 solid Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/06—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D239/08—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms directly attached in position 2
- C07D239/10—Oxygen or sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
- C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202062966665P | 2020-01-28 | 2020-01-28 | |
| US202062980503P | 2020-02-24 | 2020-02-24 | |
| US202063008009P | 2020-04-10 | 2020-04-10 | |
| PCT/US2021/015358 WO2021154904A1 (en) | 2020-01-28 | 2021-01-28 | Solid state forms of mavacamten and process for preparation thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL4097091T3 true PL4097091T3 (pl) | 2025-01-27 |
Family
ID=74669560
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL21706793.3T PL4097091T3 (pl) | 2020-01-28 | 2021-01-28 | Postacie stałe mawakamtenu i sposób ich wytwarzania |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US20230057197A1 (pl) |
| EP (2) | EP4097091B1 (pl) |
| JP (1) | JP7795063B2 (pl) |
| CN (1) | CN115515941A (pl) |
| AU (1) | AU2021213748A1 (pl) |
| CA (1) | CA3165995A1 (pl) |
| ES (1) | ES3005093T3 (pl) |
| HR (1) | HRP20241597T1 (pl) |
| HU (1) | HUE069154T2 (pl) |
| IL (1) | IL294501A (pl) |
| PL (1) | PL4097091T3 (pl) |
| SI (1) | SI4097091T1 (pl) |
| WO (1) | WO2021154904A1 (pl) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUE069154T2 (hu) | 2020-01-28 | 2025-02-28 | Assia Chem Ind Ltd | A mavakamten szilárd állapotú formái és eljárás elõállításukra |
| CN112939876A (zh) * | 2021-03-10 | 2021-06-11 | 杭州科巢生物科技有限公司 | Mavacamten的晶型I及其制备方法 |
| WO2022189599A1 (en) * | 2021-03-12 | 2022-09-15 | Sandoz Ag | Crystalline forms of mavacamten for the treatment of hcm |
| CA3248508A1 (en) | 2022-04-13 | 2023-10-19 | Assia Chemical Industries Ltd. | SOLID STATE FORMS OF MAVACAMTEN AND THEIR PREPARATION METHOD |
| WO2024134368A1 (en) * | 2022-12-23 | 2024-06-27 | Aurobindo Pharma Limited | Solid state form of mavacamten |
| WO2025046606A1 (en) | 2023-08-26 | 2025-03-06 | Micro Labs Limited | Granules of mavacamten for oral administration |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SMT202000071T1 (it) * | 2013-06-21 | 2020-03-13 | Myokardia Inc | Composti di pirimidinadione contro le condizioni cardiache |
| CA3071948A1 (en) * | 2017-08-04 | 2019-02-07 | MyoKardia, Inc. | Mavacamten for use in the treatment of hypertrophic cardiomyopathy |
| EP4054588A4 (en) * | 2019-11-10 | 2023-12-13 | MyoKardia, Inc. | Methods of treatment with myosin modulator |
| HUE069154T2 (hu) | 2020-01-28 | 2025-02-28 | Assia Chem Ind Ltd | A mavakamten szilárd állapotú formái és eljárás elõállításukra |
| US20240082248A1 (en) | 2021-02-01 | 2024-03-14 | Dr. Reddy's Laboratories Limited | Process for preparation of mavacamten and solid state forms thereof |
| CN112939876A (zh) | 2021-03-10 | 2021-06-11 | 杭州科巢生物科技有限公司 | Mavacamten的晶型I及其制备方法 |
| WO2022189599A1 (en) | 2021-03-12 | 2022-09-15 | Sandoz Ag | Crystalline forms of mavacamten for the treatment of hcm |
| CA3248508A1 (en) | 2022-04-13 | 2023-10-19 | Assia Chemical Industries Ltd. | SOLID STATE FORMS OF MAVACAMTEN AND THEIR PREPARATION METHOD |
-
2021
- 2021-01-28 HU HUE21706793A patent/HUE069154T2/hu unknown
- 2021-01-28 EP EP21706793.3A patent/EP4097091B1/en active Active
- 2021-01-28 JP JP2022546095A patent/JP7795063B2/ja active Active
- 2021-01-28 US US17/792,754 patent/US20230057197A1/en not_active Abandoned
- 2021-01-28 AU AU2021213748A patent/AU2021213748A1/en active Pending
- 2021-01-28 SI SI202130229T patent/SI4097091T1/sl unknown
- 2021-01-28 IL IL294501A patent/IL294501A/en unknown
- 2021-01-28 PL PL21706793.3T patent/PL4097091T3/pl unknown
- 2021-01-28 ES ES21706793T patent/ES3005093T3/es active Active
- 2021-01-28 CN CN202180025380.2A patent/CN115515941A/zh active Pending
- 2021-01-28 HR HRP20241597TT patent/HRP20241597T1/hr unknown
- 2021-01-28 EP EP24197956.6A patent/EP4480538A3/en active Pending
- 2021-01-28 CA CA3165995A patent/CA3165995A1/en active Pending
- 2021-01-28 WO PCT/US2021/015358 patent/WO2021154904A1/en not_active Ceased
-
2024
- 2024-03-20 US US18/610,777 patent/US12258320B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN115515941A (zh) | 2022-12-23 |
| IL294501A (en) | 2022-09-01 |
| HUE069154T2 (hu) | 2025-02-28 |
| EP4097091B1 (en) | 2024-09-18 |
| US20230057197A1 (en) | 2023-02-23 |
| AU2021213748A1 (en) | 2022-08-25 |
| US12258320B2 (en) | 2025-03-25 |
| EP4480538A2 (en) | 2024-12-25 |
| US20240228442A1 (en) | 2024-07-11 |
| ES3005093T3 (en) | 2025-03-13 |
| JP7795063B2 (ja) | 2026-01-07 |
| WO2021154904A1 (en) | 2021-08-05 |
| SI4097091T1 (sl) | 2025-05-30 |
| CA3165995A1 (en) | 2021-08-05 |
| EP4480538A3 (en) | 2025-04-02 |
| JP2023512518A (ja) | 2023-03-27 |
| HRP20241597T1 (hr) | 2025-01-31 |
| EP4097091A1 (en) | 2022-12-07 |
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