PL408984A1 - New analogues of 1,2,4-triazolophthalazines - Google Patents

New analogues of 1,2,4-triazolophthalazines

Info

Publication number
PL408984A1
PL408984A1 PL408984A PL40898414A PL408984A1 PL 408984 A1 PL408984 A1 PL 408984A1 PL 408984 A PL408984 A PL 408984A PL 40898414 A PL40898414 A PL 40898414A PL 408984 A1 PL408984 A1 PL 408984A1
Authority
PL
Poland
Prior art keywords
triazolophthalazines
analogues
new analogues
new
triazolphthalazine
Prior art date
Application number
PL408984A
Other languages
Polish (pl)
Other versions
PL224661B1 (en
Inventor
Andrzej Niewiadomy
Monika M. Karpińska
Joanna Wietrzyk
Joanna Matysiak
Mariusz Gagoś
Original Assignee
Uniwersytet Przyrodniczy W Lublinie
Instytut Przemysłu Organicznego
Instytut Immunologii i Terapii Doświadczalnej
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uniwersytet Przyrodniczy W Lublinie, Instytut Przemysłu Organicznego, Instytut Immunologii i Terapii Doświadczalnej filed Critical Uniwersytet Przyrodniczy W Lublinie
Priority to PL408984A priority Critical patent/PL224661B1/en
Priority to PCT/PL2015/000116 priority patent/WO2016013948A1/en
Publication of PL408984A1 publication Critical patent/PL408984A1/en
Publication of PL224661B1 publication Critical patent/PL224661B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Przedmiotem wynalazku są nowe analogi 1,2,4-triazoloftalazyn o wzorze ogólnym I, ze zróżnicowanym rodzajem podstawienia układu 2,4-dihydroksyfenylowego. Analogi wykazują właściwości antyproliferacyjne. Ujawniono także sposób otrzymywania nowych analogów.The present invention relates to new 1,2,4-triazolphthalazine analogues of general formula I, with different types of substitution of the 2,4-dihydroxyphenyl system. Analogs have antiproliferative properties. Also disclosed is the method of obtaining new analogues.

PL408984A 2014-07-25 2014-07-25 New analogues of 1,2,4-triazolophthalazines PL224661B1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
PL408984A PL224661B1 (en) 2014-07-25 2014-07-25 New analogues of 1,2,4-triazolophthalazines
PCT/PL2015/000116 WO2016013948A1 (en) 2014-07-25 2015-07-22 Analogs of 1,2,4-triazolophthalazines as anticancer drugs and a process for their preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL408984A PL224661B1 (en) 2014-07-25 2014-07-25 New analogues of 1,2,4-triazolophthalazines

Publications (2)

Publication Number Publication Date
PL408984A1 true PL408984A1 (en) 2016-02-01
PL224661B1 PL224661B1 (en) 2017-01-31

Family

ID=54015159

Family Applications (1)

Application Number Title Priority Date Filing Date
PL408984A PL224661B1 (en) 2014-07-25 2014-07-25 New analogues of 1,2,4-triazolophthalazines

Country Status (2)

Country Link
PL (1) PL224661B1 (en)
WO (1) WO2016013948A1 (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8343977B2 (en) * 2009-12-30 2013-01-01 Arqule, Inc. Substituted triazolo-pyrimidine compounds

Also Published As

Publication number Publication date
PL224661B1 (en) 2017-01-31
WO2016013948A1 (en) 2016-01-28

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