PL408024A1 - 2,6-di(imidazo-1-yl)hexanoic acid and method of manufacturing it - Google Patents
2,6-di(imidazo-1-yl)hexanoic acid and method of manufacturing itInfo
- Publication number
- PL408024A1 PL408024A1 PL408024A PL40802414A PL408024A1 PL 408024 A1 PL408024 A1 PL 408024A1 PL 408024 A PL408024 A PL 408024A PL 40802414 A PL40802414 A PL 40802414A PL 408024 A1 PL408024 A1 PL 408024A1
- Authority
- PL
- Poland
- Prior art keywords
- imidazo
- hexanoic acid
- parts
- manufacturing
- formula
- Prior art date
Links
- WWZKQHOCKIZLMA-UHFFFAOYSA-N Caprylic acid Natural products CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 title abstract 4
- GONOPSZTUGRENK-UHFFFAOYSA-N benzyl(trichloro)silane Chemical compound Cl[Si](Cl)(Cl)CC1=CC=CC=C1 GONOPSZTUGRENK-UHFFFAOYSA-N 0.000 title abstract 4
- FUZZWVXGSFPDMH-UHFFFAOYSA-N n-hexanoic acid Natural products CCCCCC(O)=O FUZZWVXGSFPDMH-UHFFFAOYSA-N 0.000 title abstract 4
- 238000004519 manufacturing process Methods 0.000 title 1
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 2
- LEQAOMBKQFMDFZ-UHFFFAOYSA-N glyoxal Chemical compound O=CC=O LEQAOMBKQFMDFZ-UHFFFAOYSA-N 0.000 abstract 2
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 abstract 1
- 239000004472 Lysine Substances 0.000 abstract 1
- 229910021529 ammonia Inorganic materials 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 238000004821 distillation Methods 0.000 abstract 1
- 229940015043 glyoxal Drugs 0.000 abstract 1
- WSFSSNUMVMOOMR-NJFSPNSNSA-N methanone Chemical compound O=[14CH2] WSFSSNUMVMOOMR-NJFSPNSNSA-N 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000000376 reactant Substances 0.000 abstract 1
- 159000000000 sodium salts Chemical class 0.000 abstract 1
Landscapes
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Przedmiotem wynalazku jest kwas 2,6-di(imidazo-1-yl)heksanowy przedstawiony wzorem 1. Wynalazek ujawnia również sposób wytwarzania kwasu 2,6-di(imidazo-1-yl)heksanowego o wzorze 1 charakteryzujący się tym, że lizynę poddaje się reakcji z co najmniej dwiema częściami glioksalu, co najmniej dwiema częściami amoniaku i co najmniej dwiema częściami formaldehydu oraz z co najmniej jedną częścią zasady, przy czym reakcję prowadzi się w temperaturze 298-373 K w roztworze wodnym, aż do przereagowania substratów, po czym z mieszaniny usuwa się wszystkie lotne składniki przez destylację pod zmniejszonym ciśnieniem i otrzymuje się kwas 2,6-di(imidazo-1-yl)heksanowy, korzystnie w formie soli sodowej.The present invention relates to 2,6-di (imidazo-1-yl) hexanoic acid represented by formula 1. The invention also discloses a method of producing 2,6-di (imidazo-1-yl) hexanoic acid of formula 1 characterized in that lysine is subjected to react with at least two parts of glyoxal, at least two parts of ammonia and at least two parts of formaldehyde, and with at least one part of base, the reaction being carried out at a temperature of 298-373 K in aqueous solution until the reactants react, after which all volatile components are removed from the mixture by distillation under reduced pressure to give 2,6-di (imidazo-1-yl) hexanoic acid, preferably in the form of the sodium salt.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL408024A PL229033B1 (en) | 2014-04-28 | 2014-04-28 | 2,6-di(imidazo-1-yl)hexanoic acid and method of manufacturing it |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL408024A PL229033B1 (en) | 2014-04-28 | 2014-04-28 | 2,6-di(imidazo-1-yl)hexanoic acid and method of manufacturing it |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL408024A1 true PL408024A1 (en) | 2015-02-16 |
| PL229033B1 PL229033B1 (en) | 2018-05-30 |
Family
ID=52464732
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL408024A PL229033B1 (en) | 2014-04-28 | 2014-04-28 | 2,6-di(imidazo-1-yl)hexanoic acid and method of manufacturing it |
Country Status (1)
| Country | Link |
|---|---|
| PL (1) | PL229033B1 (en) |
-
2014
- 2014-04-28 PL PL408024A patent/PL229033B1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL229033B1 (en) | 2018-05-30 |
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