PL401447A1 - Pharmaceutical composition, method for manufacture and the medical use of a combination of xylitol and nystatin in the treatment of Candida mycoses - Google Patents
Pharmaceutical composition, method for manufacture and the medical use of a combination of xylitol and nystatin in the treatment of Candida mycosesInfo
- Publication number
- PL401447A1 PL401447A1 PL401447A PL40144712A PL401447A1 PL 401447 A1 PL401447 A1 PL 401447A1 PL 401447 A PL401447 A PL 401447A PL 40144712 A PL40144712 A PL 40144712A PL 401447 A1 PL401447 A1 PL 401447A1
- Authority
- PL
- Poland
- Prior art keywords
- nystatin
- xylitol
- pharmaceutical composition
- lollipop
- combination
- Prior art date
Links
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 title abstract 5
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 title abstract 5
- 229960000988 nystatin Drugs 0.000 title abstract 5
- VQOXZBDYSJBXMA-NQTDYLQESA-N nystatin A1 Chemical compound O[C@H]1[C@@H](N)[C@H](O)[C@@H](C)O[C@H]1O[C@H]1/C=C/C=C/C=C/C=C/CC/C=C/C=C/[C@H](C)[C@@H](O)[C@@H](C)[C@H](C)OC(=O)C[C@H](O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@](O)(C[C@H](O)[C@H]2C(O)=O)O[C@H]2C1 VQOXZBDYSJBXMA-NQTDYLQESA-N 0.000 title abstract 5
- 239000000811 xylitol Substances 0.000 title abstract 5
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 title abstract 5
- 229960002675 xylitol Drugs 0.000 title abstract 5
- 235000010447 xylitol Nutrition 0.000 title abstract 5
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 3
- 241000222120 Candida <Saccharomycetales> Species 0.000 title 1
- 208000031888 Mycoses Diseases 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 235000011475 lollipops Nutrition 0.000 abstract 6
- 239000000975 dye Substances 0.000 abstract 3
- 239000000796 flavoring agent Substances 0.000 abstract 2
- 235000019634 flavors Nutrition 0.000 abstract 2
- 208000002474 Tinea Diseases 0.000 abstract 1
- 241000893966 Trichophyton verrucosum Species 0.000 abstract 1
- 229920000609 methyl cellulose Polymers 0.000 abstract 1
- 239000001923 methylcellulose Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Landscapes
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Przedmiotem wynalazku jest kompozycja farmaceutyczna w postaci lizaka, która zawiera kombinację substancji nystatyny oraz ksylitolu, aromat oraz barwnik. Sposób wytwarzania kompozycji farmaceutycznej w postaci lizaka gdzie podgrzewa się ksylitol do temperatury 95-99°C i miesza się z nystatyną w dawce 100000 - 500000 j.m., następnie dodaje się pożądany barwnik i aromat w proporcjach do smaku, wylewa się formę lizaka, którą się następnie schładza. Sposób wytwarzania kompozycji farmaceutycznej w postaci lizaka gdzie na zimno miesza się nystatynę w dawce 100000 - 500000 j.m., sproszkowany ksylitol, aromaty, barwniki oraz metylocelulozę 1% i wodę 2%, następnie prasuje się w formę lizaka i osusza próżniowo. Zastosowanie medyczne kombinacji substancji nystatyny i ksylitolu do wytwarzania formy farmaceutycznej w postaci lizaka do stosowania do leczenia grzybicy.The present invention relates to a pharmaceutical composition in the form of a lollipop, which comprises a combination of nystatin and xylitol, an aroma and a dye. The method of producing the pharmaceutical composition in the form of a lollipop where the xylitol is heated to a temperature of 95-99 ° C and mixed with nystatin in a dose of 100,000 - 500,000 IU, then the desired dye and flavor are added in proportion to taste, the lollipop is poured, which is then cools. A method of producing a pharmaceutical composition in the form of a lollipop where nystatin in a dose of 100,000 - 500,000 IU is mixed cold, powdered xylitol, flavors, dyes and methylcellulose 1% and water 2%, then pressed into a lollipop and vacuum dried. Medical use of the combination of the substance nystatin and xylitol for the preparation of a pharmaceutical form in the form of a lollipop for use in the treatment of ringworm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL401447A PL401447A1 (en) | 2012-10-31 | 2012-10-31 | Pharmaceutical composition, method for manufacture and the medical use of a combination of xylitol and nystatin in the treatment of Candida mycoses |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL401447A PL401447A1 (en) | 2012-10-31 | 2012-10-31 | Pharmaceutical composition, method for manufacture and the medical use of a combination of xylitol and nystatin in the treatment of Candida mycoses |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL401447A1 true PL401447A1 (en) | 2014-05-12 |
Family
ID=50636930
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL401447A PL401447A1 (en) | 2012-10-31 | 2012-10-31 | Pharmaceutical composition, method for manufacture and the medical use of a combination of xylitol and nystatin in the treatment of Candida mycoses |
Country Status (1)
| Country | Link |
|---|---|
| PL (1) | PL401447A1 (en) |
-
2012
- 2012-10-31 PL PL401447A patent/PL401447A1/en unknown
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