PL396494A1 - Method for determining blood groups and a system for determining blood groups - Google Patents

Method for determining blood groups and a system for determining blood groups

Info

Publication number
PL396494A1
PL396494A1 PL396494A PL39649411A PL396494A1 PL 396494 A1 PL396494 A1 PL 396494A1 PL 396494 A PL396494 A PL 396494A PL 39649411 A PL39649411 A PL 39649411A PL 396494 A1 PL396494 A1 PL 396494A1
Authority
PL
Poland
Prior art keywords
determining blood
blood groups
detector
microfluidic channel
connector
Prior art date
Application number
PL396494A
Other languages
Polish (pl)
Other versions
PL219803B1 (en
Inventor
Sylwia Makulska
Sławomir Jakieła
Piotr Garstecki
Original Assignee
Instytut Chemii Fizycznej Polskiej Akademii Nauk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Instytut Chemii Fizycznej Polskiej Akademii Nauk filed Critical Instytut Chemii Fizycznej Polskiej Akademii Nauk
Priority to PL396494A priority Critical patent/PL219803B1/en
Priority to NL2009403A priority patent/NL2009403C2/en
Publication of PL396494A1 publication Critical patent/PL396494A1/en
Publication of PL219803B1 publication Critical patent/PL219803B1/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
    • B01F25/43—Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction
    • B01F25/433—Mixing tubes wherein the shape of the tube influences the mixing, e.g. mixing tubes with varying cross-section or provided with inwardly extending profiles
    • B01F25/4331—Mixers with bended, curved, coiled, wounded mixing tubes or comprising elements for bending the flow
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B01F33/302—Micromixers the materials to be mixed flowing in the form of droplets
    • B01F33/3021—Micromixers the materials to be mixed flowing in the form of droplets the components to be mixed being combined in a single independent droplet, e.g. these droplets being divided by a non-miscible fluid or consisting of independent droplets
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/80—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood groups or blood types or red blood cells
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0883—Serpentine channels
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Clinical Laboratory Science (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)

Abstract

Przedmiotem wynalazku jest sposób oznaczania grupy krwi, obejmujący otrzymanie próbki (11) poprzez zmieszanie materiału badanego (8) z materiałem wzorcowym (9) oraz detekcję aglutynacji w tak otrzymanej próbce (11), charakteryzujący się tym, że wspomnianego zmieszania materiału badanego (8) z materiałem wzorcowym (9) dokonuje się w kanale (3) układu mikroprzepływowego. Wynalazek obejmuje także układ do oznaczania grupy krwi, obejmujący pierwszy kanał mikroprzepływowy (1) i drugi kanał mikroprzepływowy (2), łączące się w złączu (3) oraz trzeci kanał mikroprzepływowy (5), prowadzący od tego złącza (3) do pierwszego detektora (6), charakteryzujący się tym, że wspomnianym pierwszym detektorem (6) jest detektor czuły na zmianę natężenia światła.The subject of the invention is a method for determining blood group, comprising obtaining a sample (11) by mixing a test material (8) with a reference material (9) and detecting agglutination in the sample (11) thus obtained, characterized in that said mixing of the test material (8) with the reference material (9) is carried out in a channel (3) of a microfluidic system. The invention also includes a system for determining blood group, comprising a first microfluidic channel (1) and a second microfluidic channel (2), connecting in a connector (3), and a third microfluidic channel (5), leading from said connector (3) to a first detector (6), characterized in that said first detector (6) is a detector sensitive to a change in light intensity.

PL396494A 2011-09-30 2011-09-30 Method for determining blood groups and a system for determining blood groups PL219803B1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
PL396494A PL219803B1 (en) 2011-09-30 2011-09-30 Method for determining blood groups and a system for determining blood groups
NL2009403A NL2009403C2 (en) 2011-09-30 2012-09-03 Method for determination of blood group and system for the same.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL396494A PL219803B1 (en) 2011-09-30 2011-09-30 Method for determining blood groups and a system for determining blood groups

Publications (2)

Publication Number Publication Date
PL396494A1 true PL396494A1 (en) 2013-04-02
PL219803B1 PL219803B1 (en) 2015-07-31

Family

ID=48040876

Family Applications (1)

Application Number Title Priority Date Filing Date
PL396494A PL219803B1 (en) 2011-09-30 2011-09-30 Method for determining blood groups and a system for determining blood groups

Country Status (2)

Country Link
NL (1) NL2009403C2 (en)
PL (1) PL219803B1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3025781A1 (en) 2014-11-28 2016-06-01 Geomobile Sp. z o.o. A method for determinig agglutination

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3025781A1 (en) 2014-11-28 2016-06-01 Geomobile Sp. z o.o. A method for determinig agglutination

Also Published As

Publication number Publication date
NL2009403A (en) 2013-04-03
NL2009403C2 (en) 2013-08-14
PL219803B1 (en) 2015-07-31

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