PL3920912T3 - Leczenie ciliopatii przy użyciu inhibitorów syntazy glukozyloceramidowej (gcs) - Google Patents
Leczenie ciliopatii przy użyciu inhibitorów syntazy glukozyloceramidowej (gcs)Info
- Publication number
- PL3920912T3 PL3920912T3 PL20709049.9T PL20709049T PL3920912T3 PL 3920912 T3 PL3920912 T3 PL 3920912T3 PL 20709049 T PL20709049 T PL 20709049T PL 3920912 T3 PL3920912 T3 PL 3920912T3
- Authority
- PL
- Poland
- Prior art keywords
- ciliopathies
- gcs
- inhibitors
- treatment
- glucosylceramide synthase
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962800993P | 2019-02-04 | 2019-02-04 | |
| US201962851430P | 2019-05-22 | 2019-05-22 | |
| PCT/US2020/016588 WO2020163337A1 (en) | 2019-02-04 | 2020-02-04 | Treatment of ciliopathies using inhibitors of glucosylceramide synthase (gcs) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3920912T3 true PL3920912T3 (pl) | 2025-11-12 |
Family
ID=69740838
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL20709049.9T PL3920912T3 (pl) | 2019-02-04 | 2020-02-04 | Leczenie ciliopatii przy użyciu inhibitorów syntazy glukozyloceramidowej (gcs) |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20220110922A1 (pl) |
| EP (1) | EP3920912B1 (pl) |
| JP (1) | JP7633169B2 (pl) |
| CN (1) | CN114040762A (pl) |
| AU (1) | AU2020218185B2 (pl) |
| CA (1) | CA3128043A1 (pl) |
| ES (1) | ES3040555T3 (pl) |
| HU (1) | HUE072626T2 (pl) |
| PL (1) | PL3920912T3 (pl) |
| PT (1) | PT3920912T (pl) |
| WO (1) | WO2020163337A1 (pl) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JOP20130273B1 (ar) | 2012-09-11 | 2021-08-17 | Genzyme Corp | مثبطات انزيم (سينثاز) غلوكوسيل سيراميد |
| IL295255A (en) | 2020-02-03 | 2022-10-01 | Genzyme Corp | Methods for treating neurological symptoms associated with lysosomal storage diseases |
| MX2023001014A (es) | 2020-07-24 | 2023-03-01 | Genzyme Corp | Composiciones farmaceuticas que comprenden venglustat. |
| WO2022169004A1 (ko) * | 2021-02-05 | 2022-08-11 | 연세대학교 산학협력단 | 신규한 fabp4 억제제를 유효성분으로 포함하는 섬모형성 촉진용 조성물 |
| EP4201403A1 (en) | 2021-12-21 | 2023-06-28 | Som Innovation Biotech, S.L. | Compounds tirapazamine and quazinone for use in the treatment of gm2 gangliosidoses |
| CN115350278A (zh) * | 2022-07-11 | 2022-11-18 | 清华大学 | 提高细胞内鞘脂类物质含量的试剂在制备纤毛异常相关疾病药物中的用途 |
| WO2024116127A1 (en) | 2022-12-01 | 2024-06-06 | Genzyme Corporation | Venglustat in combination with a strong or moderate inhibitor of cyp3a4 |
| WO2025178019A1 (ja) * | 2024-02-19 | 2025-08-28 | 国立大学法人大阪大学 | 繊毛病治療用医薬組成物 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE640616A (pl) | 1962-12-19 | |||
| US3492397A (en) | 1967-04-07 | 1970-01-27 | Warner Lambert Pharmaceutical | Sustained release dosage in the pellet form and process thereof |
| US4060598A (en) | 1967-06-28 | 1977-11-29 | Boehringer Mannheim G.M.B.H. | Tablets coated with aqueous resin dispersions |
| US3538214A (en) | 1969-04-22 | 1970-11-03 | Merck & Co Inc | Controlled release medicinal tablets |
| US4173626A (en) | 1978-12-11 | 1979-11-06 | Merck & Co., Inc. | Sustained release indomethacin |
| LT3673906T (lt) | 2011-03-18 | 2025-08-11 | Genzyme Corporation | Gliukozilceramido sintazės inhibitoriai |
| JOP20130273B1 (ar) | 2012-09-11 | 2021-08-17 | Genzyme Corp | مثبطات انزيم (سينثاز) غلوكوسيل سيراميد |
| JO3713B1 (ar) | 2013-03-15 | 2021-01-31 | Genzyme Corp | أشكال ملح (s)-كوينوكليدين-3-يل(2-(2-(4-فلوروفينيل)ثيازول-4-يل)بروبان-2-يل)كارباميت |
| TW201642855A (zh) * | 2015-03-10 | 2016-12-16 | 健臻公司 | 用於治療蛋白質病變之方法 |
| JP6895963B2 (ja) * | 2015-11-18 | 2021-06-30 | ジェンザイム・コーポレーション | 多発性嚢胞腎のバイオマーカーおよびその使用 |
| US10588888B2 (en) * | 2017-07-17 | 2020-03-17 | Children's Hospital Medical Center | CNS-accessible pharmacological chaperones for treatment of acid β-glucosidase-related disease states |
-
2020
- 2020-02-04 PT PT207090499T patent/PT3920912T/pt unknown
- 2020-02-04 EP EP20709049.9A patent/EP3920912B1/en active Active
- 2020-02-04 US US17/428,502 patent/US20220110922A1/en active Pending
- 2020-02-04 AU AU2020218185A patent/AU2020218185B2/en active Active
- 2020-02-04 HU HUE20709049A patent/HUE072626T2/hu unknown
- 2020-02-04 JP JP2021545384A patent/JP7633169B2/ja active Active
- 2020-02-04 ES ES20709049T patent/ES3040555T3/es active Active
- 2020-02-04 CA CA3128043A patent/CA3128043A1/en active Pending
- 2020-02-04 CN CN202080025851.5A patent/CN114040762A/zh active Pending
- 2020-02-04 PL PL20709049.9T patent/PL3920912T3/pl unknown
- 2020-02-04 WO PCT/US2020/016588 patent/WO2020163337A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| JP2022519131A (ja) | 2022-03-18 |
| PT3920912T (pt) | 2025-09-09 |
| CN114040762A (zh) | 2022-02-11 |
| EP3920912A1 (en) | 2021-12-15 |
| AU2020218185A1 (en) | 2021-08-26 |
| EP3920912B1 (en) | 2025-06-11 |
| ES3040555T3 (en) | 2025-11-03 |
| WO2020163337A1 (en) | 2020-08-13 |
| US20220110922A1 (en) | 2022-04-14 |
| CA3128043A1 (en) | 2020-08-13 |
| JP7633169B2 (ja) | 2025-02-19 |
| AU2020218185B2 (en) | 2025-01-23 |
| HUE072626T2 (hu) | 2025-11-28 |
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