PL380335A1 - Sekwencja dwunicowego ATN-RNA, interwencja interferencyjnym RNA ( iRnAi) oraz zastosowanie sekwencji dwunicowego ATN-RNA w terapii guzów mózgu - Google Patents

Sekwencja dwunicowego ATN-RNA, interwencja interferencyjnym RNA ( iRnAi) oraz zastosowanie sekwencji dwunicowego ATN-RNA w terapii guzów mózgu

Info

Publication number
PL380335A1
PL380335A1 PL380335A PL38033506A PL380335A1 PL 380335 A1 PL380335 A1 PL 380335A1 PL 380335 A PL380335 A PL 380335A PL 38033506 A PL38033506 A PL 38033506A PL 380335 A1 PL380335 A1 PL 380335A1
Authority
PL
Poland
Prior art keywords
rna
atn
stranded
sequence
double
Prior art date
Application number
PL380335A
Other languages
English (en)
Inventor
Jan Barciszewski
Mirosława Barciszewska
Leszek Rychlewski
Eliza Wyszko
Iwona Gawrońska
Ryszard Żukiel
Katarzyna Rolle
Stanisław Nowak
Original Assignee
Instytut Chemii Bioorganicznej Pan W Poznaniu
Bioinfobank Spółka Z Ograniczoną Odpowiedzialnością
Uniwersytet Medyczny Im. Karola Marcinkowskiego W Poznaniu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Instytut Chemii Bioorganicznej Pan W Poznaniu, Bioinfobank Spółka Z Ograniczoną Odpowiedzialnością, Uniwersytet Medyczny Im. Karola Marcinkowskiego W Poznaniu filed Critical Instytut Chemii Bioorganicznej Pan W Poznaniu
Priority to PL380335A priority Critical patent/PL380335A1/pl
Priority to PCT/PL2007/000054 priority patent/WO2008016317A2/en
Priority to EP07793958A priority patent/EP2121927B1/en
Priority to PL07793958T priority patent/PL2121927T3/pl
Priority to US12/375,916 priority patent/US8946400B2/en
Publication of PL380335A1 publication Critical patent/PL380335A1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1136—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against growth factors, growth regulators, cytokines, lymphokines or hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL380335A 2006-07-31 2006-07-31 Sekwencja dwunicowego ATN-RNA, interwencja interferencyjnym RNA ( iRnAi) oraz zastosowanie sekwencji dwunicowego ATN-RNA w terapii guzów mózgu PL380335A1 (pl)

Priority Applications (5)

Application Number Priority Date Filing Date Title
PL380335A PL380335A1 (pl) 2006-07-31 2006-07-31 Sekwencja dwunicowego ATN-RNA, interwencja interferencyjnym RNA ( iRnAi) oraz zastosowanie sekwencji dwunicowego ATN-RNA w terapii guzów mózgu
PCT/PL2007/000054 WO2008016317A2 (en) 2006-07-31 2007-07-30 A sequence of dsrna: atn-rna, intervention using irnai, use of a sequence of dsrna: atn-rna, a method of treating and inhibiting a brain tumor, a kit for inhibiting cancer cell which expresses tenascin, a method for a kit preparation in a brain tumor therapy
EP07793958A EP2121927B1 (en) 2006-07-31 2007-07-30 A sequence of dsrna: atn-rna, intervention using irnai, use of a sequence of dsrna: atn-rna, a method of treating and inhibiting a brain tumor, a kit for inhibiting cancer cell which expresses tenascin, a method for a kit preparation in a brain tumor therapy
PL07793958T PL2121927T3 (pl) 2006-07-31 2007-07-30 Sekwencja dsRNA: ATN-RNA, interwencja przy użyciu IRNAI, zastosowanie sekwencji dsRNA: ATN-RNA, sposób leczenia i inhibicji guza mózgu, zestaw do inhibicji komórek nowotworowych, które eksprymują tenascynę, sposób otrzymywania zestawu w terapii guzów mózgu
US12/375,916 US8946400B2 (en) 2006-07-31 2007-07-30 Sequence of dsRNA: ATN-RNA specific for tenascin-C

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL380335A PL380335A1 (pl) 2006-07-31 2006-07-31 Sekwencja dwunicowego ATN-RNA, interwencja interferencyjnym RNA ( iRnAi) oraz zastosowanie sekwencji dwunicowego ATN-RNA w terapii guzów mózgu

Publications (1)

Publication Number Publication Date
PL380335A1 true PL380335A1 (pl) 2008-02-04

Family

ID=38776304

Family Applications (2)

Application Number Title Priority Date Filing Date
PL380335A PL380335A1 (pl) 2006-07-31 2006-07-31 Sekwencja dwunicowego ATN-RNA, interwencja interferencyjnym RNA ( iRnAi) oraz zastosowanie sekwencji dwunicowego ATN-RNA w terapii guzów mózgu
PL07793958T PL2121927T3 (pl) 2006-07-31 2007-07-30 Sekwencja dsRNA: ATN-RNA, interwencja przy użyciu IRNAI, zastosowanie sekwencji dsRNA: ATN-RNA, sposób leczenia i inhibicji guza mózgu, zestaw do inhibicji komórek nowotworowych, które eksprymują tenascynę, sposób otrzymywania zestawu w terapii guzów mózgu

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL07793958T PL2121927T3 (pl) 2006-07-31 2007-07-30 Sekwencja dsRNA: ATN-RNA, interwencja przy użyciu IRNAI, zastosowanie sekwencji dsRNA: ATN-RNA, sposób leczenia i inhibicji guza mózgu, zestaw do inhibicji komórek nowotworowych, które eksprymują tenascynę, sposób otrzymywania zestawu w terapii guzów mózgu

Country Status (4)

Country Link
US (1) US8946400B2 (pl)
EP (1) EP2121927B1 (pl)
PL (2) PL380335A1 (pl)
WO (1) WO2008016317A2 (pl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011107586A1 (en) * 2010-03-05 2011-09-09 Novartis Forschungsstiftung, Zweigniederlassung, Friedrich Miescher Institute For Biomedical Research, Smoc1, tenascin-c and brain cancers
EP4526449A2 (en) * 2022-05-17 2025-03-26 Medicofarma Biotech SA Sirna molecule against human tenascin-c (tnc) and a pharmaceutical composition comprising it

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6506559B1 (en) * 1997-12-23 2003-01-14 Carnegie Institute Of Washington Genetic inhibition by double-stranded RNA
AUPP249298A0 (en) * 1998-03-20 1998-04-23 Ag-Gene Australia Limited Synthetic genes and genetic constructs comprising same I
AU5124199A (en) 1998-07-27 2000-02-21 Virginia Commonwealth University Exon deletion antisense drug design and therapy
WO2005095622A2 (en) 2004-03-26 2005-10-13 Van Andel Research Institute c-met siRNA ADENOVIRUS VECTORS INHIBIT CANCER CELL GROWTH, INVASION AND TUMORIGENICITY

Also Published As

Publication number Publication date
EP2121927A2 (en) 2009-11-25
EP2121927B1 (en) 2012-10-10
PL2121927T3 (pl) 2013-05-31
US20100076053A1 (en) 2010-03-25
WO2008016317A2 (en) 2008-02-07
US8946400B2 (en) 2015-02-03
WO2008016317A3 (en) 2008-03-20

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