PL3701009T3 - Prezentacja heterologicznych cząsteczek na komórkach bakteryjnych i pęcherzykach błonowych - Google Patents

Prezentacja heterologicznych cząsteczek na komórkach bakteryjnych i pęcherzykach błonowych

Info

Publication number
PL3701009T3
PL3701009T3 PL18800517.7T PL18800517T PL3701009T3 PL 3701009 T3 PL3701009 T3 PL 3701009T3 PL 18800517 T PL18800517 T PL 18800517T PL 3701009 T3 PL3701009 T3 PL 3701009T3
Authority
PL
Poland
Prior art keywords
display
bacterial cells
membrane vesicles
heterologous molecules
heterologous
Prior art date
Application number
PL18800517.7T
Other languages
English (en)
Inventor
Hendrik Bart VAN DEN BERG VAN SAPAROEA
Wouter Simon Petrus Jong
Joen Luirink
Original Assignee
Abera Bioscience Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abera Bioscience Ab filed Critical Abera Bioscience Ab
Publication of PL3701009T3 publication Critical patent/PL3701009T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245—Escherichia (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C07K14/3156—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/7056—Lectin superfamily, e.g. CD23, CD72
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/569—Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2503/00—Use of cells in diagnostics
    • C12N2503/02—Drug screening

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pulmonology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
PL18800517.7T 2017-10-25 2018-10-25 Prezentacja heterologicznych cząsteczek na komórkach bakteryjnych i pęcherzykach błonowych PL3701009T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP17198241 2017-10-25
PCT/EP2018/079355 WO2019081685A1 (en) 2017-10-25 2018-10-25 EXPOSURE OF HETEROLOGOUS MOLECULES TO BACTERIAL CELLS AND MEMBRANE VESICLES

Publications (1)

Publication Number Publication Date
PL3701009T3 true PL3701009T3 (pl) 2025-04-14

Family

ID=64270821

Family Applications (1)

Application Number Title Priority Date Filing Date
PL18800517.7T PL3701009T3 (pl) 2017-10-25 2018-10-25 Prezentacja heterologicznych cząsteczek na komórkach bakteryjnych i pęcherzykach błonowych

Country Status (5)

Country Link
US (1) US11059868B2 (pl)
EP (2) EP4524157A3 (pl)
ES (1) ES3015058T3 (pl)
PL (1) PL3701009T3 (pl)
WO (1) WO2019081685A1 (pl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB202009411D0 (en) * 2020-06-19 2020-08-05 Prokarium Ltd Autotransporter systems
CN112773901B (zh) * 2021-01-29 2022-03-15 国家纳米科学中心 细菌外膜囊泡载体及其制备方法与应用
AU2023293070A1 (en) * 2022-06-13 2025-01-09 Trustees Of Tufts College Methods for spore display
WO2025132910A2 (en) * 2023-12-22 2025-06-26 Abera Bioscience Ab Cell-free production method and uses
WO2025242766A1 (en) 2024-05-22 2025-11-27 Abera Bioscience Ab Pneumococcal vaccine

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2450054T3 (en) 2007-04-12 2018-08-13 Stichting Katholieke Univ New virulence factors of Streptococcus pneumoniae
GB201002362D0 (en) 2010-02-11 2010-03-31 Isis Innovation Peptide tag systems that spontaneously form an irreversible link to protein partners via isopeptide bonds
WO2012041899A1 (en) 2010-09-28 2012-04-05 Xbrane Bioscience Ab Fusion protein for secretory protein expression
US9862048B2 (en) 2010-10-07 2018-01-09 Illinois Tool Works Inc. Method and apparatus for monitoring weld cell
AU2016207099C1 (en) * 2015-01-15 2021-02-04 University Of Copenhagen Virus-like particle with efficient epitope display
US20160222372A1 (en) 2015-01-30 2016-08-04 The Government Of The United States Of America, As Represented By The Secretary Of The Navy Enzyme/Protein Packaged Bacterial Vesicles for Therapeutic Delivery
GB201509782D0 (en) 2015-06-05 2015-07-22 Isis Innovation Methods and products for fusion protein synthesis
US20170258885A1 (en) 2016-03-14 2017-09-14 Abera Bioscience Ab Fusion protein comprising streptococcal antigen

Also Published As

Publication number Publication date
EP4524157A2 (en) 2025-03-19
EP3701009A1 (en) 2020-09-02
EP3701009B1 (en) 2024-12-18
WO2019081685A1 (en) 2019-05-02
ES3015058T3 (en) 2025-04-29
EP4524157A3 (en) 2025-06-18
US20200377556A1 (en) 2020-12-03
EP3701009C0 (en) 2024-12-18
US11059868B2 (en) 2021-07-13

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