PL3633681T3 - Sposób i system do przewidywania powinowactwa wiązania oraz sposób wytwarzania potencjalnie użytecznego peptydu wiążącego białka - Google Patents

Sposób i system do przewidywania powinowactwa wiązania oraz sposób wytwarzania potencjalnie użytecznego peptydu wiążącego białka

Info

Publication number
PL3633681T3
PL3633681T3 PL18198984.9T PL18198984T PL3633681T3 PL 3633681 T3 PL3633681 T3 PL 3633681T3 PL 18198984 T PL18198984 T PL 18198984T PL 3633681 T3 PL3633681 T3 PL 3633681T3
Authority
PL
Poland
Prior art keywords
generating
binding
candidate protein
affinity prediction
binding affinity
Prior art date
Application number
PL18198984.9T
Other languages
English (en)
Inventor
Marius Eidsaa
Richard STRATFORD
Trevor CLANCY
Original Assignee
Nec Oncoimmunity As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nec Oncoimmunity As filed Critical Nec Oncoimmunity As
Publication of PL3633681T3 publication Critical patent/PL3633681T3/pl

Links

Classifications

    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/30—Detection of binding sites or motifs
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B15/00—ICT specially adapted for analysing two-dimensional or three-dimensional molecular structures, e.g. structural or functional relations or structure alignment
    • G16B15/30—Drug targeting using structural data; Docking or binding prediction

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Theoretical Computer Science (AREA)
  • Medical Informatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biotechnology (AREA)
  • Evolutionary Biology (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Information Retrieval, Db Structures And Fs Structures Therefor (AREA)
  • Peptides Or Proteins (AREA)
PL18198984.9T 2018-10-05 2018-10-05 Sposób i system do przewidywania powinowactwa wiązania oraz sposób wytwarzania potencjalnie użytecznego peptydu wiążącego białka PL3633681T3 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP18198984.9A EP3633681B1 (en) 2018-10-05 2018-10-05 Method and system for binding affinity prediction and method of generating a candidate protein-binding peptide

Publications (1)

Publication Number Publication Date
PL3633681T3 true PL3633681T3 (pl) 2024-04-22

Family

ID=63787867

Family Applications (1)

Application Number Title Priority Date Filing Date
PL18198984.9T PL3633681T3 (pl) 2018-10-05 2018-10-05 Sposób i system do przewidywania powinowactwa wiązania oraz sposób wytwarzania potencjalnie użytecznego peptydu wiążącego białka

Country Status (8)

Country Link
US (1) US20210391032A1 (pl)
EP (1) EP3633681B1 (pl)
JP (1) JP7410138B2 (pl)
CN (1) CN113168887B (pl)
CA (1) CA3115180A1 (pl)
ES (1) ES2970582T3 (pl)
PL (1) PL3633681T3 (pl)
WO (1) WO2020070307A1 (pl)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021214081A2 (en) 2020-04-20 2021-10-28 Nec Oncoimmunity As Sars-cov-2 vaccines
CA3176326A1 (en) 2020-04-20 2021-10-28 Boris SIMOVSKI Method and system for identifying one or more candidate regions of one or more source proteins that are predicted to instigate an immunogenic response, and method for creating a vaccine
EP3901954A1 (en) 2020-04-20 2021-10-27 NEC OncoImmunity AS Method and system for identifying one or more candidate regions of one or more source proteins that are predicted to instigate an immunogenic response, and method for creating a vaccine
BR112022012316A2 (pt) 2020-04-20 2022-11-16 NEC Laboratories Europe GmbH Método implementado por computador de selecionar uma ou mais sequências de aminoácidos para inclusão em uma vacina a partir de um conjunto de sequências de aminoácidos candidatas imunogênicas previstas; método de criação de uma vacina; sistema para selecionar uma ou mais sequências de aminoácidos para inclusão em uma vacina a partir de um conjunto de sequências de aminoácidos candidatas imunogênicas previstas; e; meio legível por computador
CN111951887A (zh) * 2020-07-27 2020-11-17 深圳市新合生物医疗科技有限公司 基于深度学习的白细胞抗原与多肽结合亲和力预测方法
CN114120006B (zh) * 2020-08-28 2024-02-06 腾讯科技（深圳）有限公司 图像处理方法、装置、电子设备和计算机可读存储介质
WO2023230077A1 (en) * 2022-05-23 2023-11-30 Palepu Kalyan Contrastive learning for peptide based degrader design and uses thereof
CN115798595B (zh) * 2023-01-30 2023-05-09 深圳新合睿恩生物医疗科技有限公司 蛋白质序列的水解位点预测方法及装置、设备、存储介质
CN116844637B (zh) * 2023-07-07 2024-02-09 北京分子之心科技有限公司 一种获取第一源抗体序列对应的第二源蛋白质序列的方法与设备

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040072249A1 (en) * 2002-06-28 2004-04-15 Hoffman Stephen L. Methods for peptide-protein binding prediction
US8145437B2 (en) * 2005-06-24 2012-03-27 Jan Biro System and method to obtain oligo-peptides with specific high affinity to query proteins
JP5339111B2 (ja) * 2007-03-08 2013-11-13 国立大学法人 千葉大学 分子設計装置、分子設計方法及びプログラム
BR112012006727A2 (pt) * 2009-09-25 2019-09-24 Shanghai National Engineering Res Center Of Antibody Medicine Co Ltd método de aquisição de proteínas com alta afinidade por um desenho auxiliado por computador
US10706955B2 (en) 2010-03-23 2020-07-07 Iogenetics, Llc Bioinformatic processes for determination of peptide binding
CN102509029A (zh) * 2011-10-26 2012-06-20 重庆教育学院 人类1型双载蛋白Src同源结构域3结合肽的亲和力预测及分析方法
US20160132631A1 (en) * 2013-06-10 2016-05-12 Iogenetics, Llc Bioinformatic processes for determination of peptide binding
CN107038348B (zh) * 2017-05-04 2020-03-10 四川大学 基于蛋白-配体相互作用指纹图谱的药物靶标预测方法

Also Published As

Publication number Publication date
CN113168887B (zh) 2024-03-19
JP7410138B2 (ja) 2024-01-09
EP3633681A1 (en) 2020-04-08
US20210391032A1 (en) 2021-12-16
EP3633681C0 (en) 2024-01-03
WO2020070307A1 (en) 2020-04-09
CN113168887A (zh) 2021-07-23
JP2022512612A (ja) 2022-02-07
EP3633681B1 (en) 2024-01-03
CA3115180A1 (en) 2020-04-09
ES2970582T3 (es) 2024-05-29

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