PL3633681T3 - Sposób i system do przewidywania powinowactwa wiązania oraz sposób wytwarzania potencjalnie użytecznego peptydu wiążącego białka - Google Patents
Sposób i system do przewidywania powinowactwa wiązania oraz sposób wytwarzania potencjalnie użytecznego peptydu wiążącego białkaInfo
- Publication number
- PL3633681T3 PL3633681T3 PL18198984.9T PL18198984T PL3633681T3 PL 3633681 T3 PL3633681 T3 PL 3633681T3 PL 18198984 T PL18198984 T PL 18198984T PL 3633681 T3 PL3633681 T3 PL 3633681T3
- Authority
- PL
- Poland
- Prior art keywords
- generating
- binding
- candidate protein
- affinity prediction
- binding affinity
- Prior art date
Links
- 238000000034 method Methods 0.000 title 2
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
Classifications
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
- G16B20/30—Detection of binding sites or motifs
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B15/00—ICT specially adapted for analysing two-dimensional or three-dimensional molecular structures, e.g. structural or functional relations or structure alignment
- G16B15/30—Drug targeting using structural data; Docking or binding prediction
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Spectroscopy & Molecular Physics (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Theoretical Computer Science (AREA)
- Medical Informatics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Biotechnology (AREA)
- Evolutionary Biology (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Crystallography & Structural Chemistry (AREA)
- Information Retrieval, Db Structures And Fs Structures Therefor (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP18198984.9A EP3633681B1 (en) | 2018-10-05 | 2018-10-05 | Method and system for binding affinity prediction and method of generating a candidate protein-binding peptide |
Publications (1)
Publication Number | Publication Date |
---|---|
PL3633681T3 true PL3633681T3 (pl) | 2024-04-22 |
Family
ID=63787867
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL18198984.9T PL3633681T3 (pl) | 2018-10-05 | 2018-10-05 | Sposób i system do przewidywania powinowactwa wiązania oraz sposób wytwarzania potencjalnie użytecznego peptydu wiążącego białka |
Country Status (8)
Country | Link |
---|---|
US (1) | US20210391032A1 (pl) |
EP (1) | EP3633681B1 (pl) |
JP (1) | JP7410138B2 (pl) |
CN (1) | CN113168887B (pl) |
CA (1) | CA3115180A1 (pl) |
ES (1) | ES2970582T3 (pl) |
PL (1) | PL3633681T3 (pl) |
WO (1) | WO2020070307A1 (pl) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN116406472A (zh) | 2020-04-20 | 2023-07-07 | Nec奥克尔姆内特公司 | 用于鉴定经预测以激发免疫原性响应的一种或多种源蛋白的一个或多个候选区的方法和系统以及用于产生疫苗的方法 |
EP4138895A2 (en) | 2020-04-20 | 2023-03-01 | NEC OncoImmunity AS | Sars-cov-2 vaccines |
AU2020443560B2 (en) | 2020-04-20 | 2024-03-21 | Nec Corporation | A method and a system for optimal vaccine design |
EP3901954A1 (en) | 2020-04-20 | 2021-10-27 | NEC OncoImmunity AS | Method and system for identifying one or more candidate regions of one or more source proteins that are predicted to instigate an immunogenic response, and method for creating a vaccine |
CN114120006B (zh) * | 2020-08-28 | 2024-02-06 | 腾讯科技(深圳)有限公司 | 图像处理方法、装置、电子设备和计算机可读存储介质 |
WO2023230077A1 (en) * | 2022-05-23 | 2023-11-30 | Palepu Kalyan | Contrastive learning for peptide based degrader design and uses thereof |
CN115798595B (zh) * | 2023-01-30 | 2023-05-09 | 深圳新合睿恩生物医疗科技有限公司 | 蛋白质序列的水解位点预测方法及装置、设备、存储介质 |
CN116844637B (zh) * | 2023-07-07 | 2024-02-09 | 北京分子之心科技有限公司 | 一种获取第一源抗体序列对应的第二源蛋白质序列的方法与设备 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040072249A1 (en) * | 2002-06-28 | 2004-04-15 | Hoffman Stephen L. | Methods for peptide-protein binding prediction |
US8145437B2 (en) * | 2005-06-24 | 2012-03-27 | Jan Biro | System and method to obtain oligo-peptides with specific high affinity to query proteins |
JP5339111B2 (ja) * | 2007-03-08 | 2013-11-13 | 国立大学法人 千葉大学 | 分子設計装置、分子設計方法及びプログラム |
JP2013505707A (ja) * | 2009-09-25 | 2013-02-21 | 上海抗体薬物国家工程研究中心有限公司 | コンピュータ支援設計により高親和性の抗体又はタンパク質分子を得る方法 |
WO2011119484A1 (en) * | 2010-03-23 | 2011-09-29 | Iogenetics, Llc | Bioinformatic processes for determination of peptide binding |
CN102509029A (zh) * | 2011-10-26 | 2012-06-20 | 重庆教育学院 | 人类1型双载蛋白Src同源结构域3结合肽的亲和力预测及分析方法 |
US20160132631A1 (en) * | 2013-06-10 | 2016-05-12 | Iogenetics, Llc | Bioinformatic processes for determination of peptide binding |
CN107038348B (zh) * | 2017-05-04 | 2020-03-10 | 四川大学 | 基于蛋白-配体相互作用指纹图谱的药物靶标预测方法 |
-
2018
- 2018-10-05 ES ES18198984T patent/ES2970582T3/es active Active
- 2018-10-05 PL PL18198984.9T patent/PL3633681T3/pl unknown
- 2018-10-05 EP EP18198984.9A patent/EP3633681B1/en active Active
-
2019
- 2019-10-04 JP JP2021518717A patent/JP7410138B2/ja active Active
- 2019-10-04 CA CA3115180A patent/CA3115180A1/en active Pending
- 2019-10-04 WO PCT/EP2019/076954 patent/WO2020070307A1/en active Application Filing
- 2019-10-04 US US17/282,708 patent/US20210391032A1/en active Pending
- 2019-10-04 CN CN201980079028.XA patent/CN113168887B/zh active Active
Also Published As
Publication number | Publication date |
---|---|
EP3633681A1 (en) | 2020-04-08 |
EP3633681C0 (en) | 2024-01-03 |
EP3633681B1 (en) | 2024-01-03 |
CN113168887A (zh) | 2021-07-23 |
CA3115180A1 (en) | 2020-04-09 |
JP2022512612A (ja) | 2022-02-07 |
US20210391032A1 (en) | 2021-12-16 |
CN113168887B (zh) | 2024-03-19 |
JP7410138B2 (ja) | 2024-01-09 |
WO2020070307A1 (en) | 2020-04-09 |
ES2970582T3 (es) | 2024-05-29 |
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