PL359926A1 - Agonist anti-trk-c monoclonal antibodies - Google Patents

Agonist anti-trk-c monoclonal antibodies

Info

Publication number
PL359926A1
PL359926A1 PL35992601A PL35992601A PL359926A1 PL 359926 A1 PL359926 A1 PL 359926A1 PL 35992601 A PL35992601 A PL 35992601A PL 35992601 A PL35992601 A PL 35992601A PL 359926 A1 PL359926 A1 PL 359926A1
Authority
PL
Poland
Prior art keywords
monoclonal antibodies
agonist anti
trk
trkc
antibodies
Prior art date
Application number
PL35992601A
Other languages
Polish (pl)
Other versions
PL208113B1 (en
Inventor
Brigitte Devaux
Jo-Anne S. Hongo
Leonard G. Presta
David L. Shelton
Original Assignee
Genentech, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech, Inc. filed Critical Genentech, Inc.
Publication of PL359926A1 publication Critical patent/PL359926A1/en
Publication of PL208113B1 publication Critical patent/PL208113B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Neurology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The invention concerns agonist anti-trkC monoclonal antibodies which mimic certain biological activities of NT-3, the native ligand of trkC. The invention further concerns the use of such antibodies in the prevention and/or treatment of cellular degeneration, including nerve cell damage associated with acute nervous cell system injury and chronic neurodegenerative diseases, including peripheral neuropathy.
PL359926A 2000-06-22 2001-06-22 Agonist anti-trk-c monoclonal antibodies PL208113B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US21314100P 2000-06-22 2000-06-22
US23831900P 2000-10-05 2000-10-05
PCT/US2001/020153 WO2001098361A2 (en) 2000-06-22 2001-06-22 Agonist anti-trk-c monoclonal antibodies

Publications (2)

Publication Number Publication Date
PL359926A1 true PL359926A1 (en) 2004-09-06
PL208113B1 PL208113B1 (en) 2011-03-31

Family

ID=26907807

Family Applications (1)

Application Number Title Priority Date Filing Date
PL359926A PL208113B1 (en) 2000-06-22 2001-06-22 Agonist anti-trk-c monoclonal antibodies

Country Status (17)

Country Link
US (4) US7384632B2 (en)
EP (1) EP1292680B1 (en)
JP (1) JP2004500873A (en)
KR (1) KR100823764B1 (en)
CN (1) CN100519749C (en)
AT (1) ATE446366T1 (en)
AU (2) AU7142201A (en)
BR (1) BR0112272A (en)
CA (1) CA2412494C (en)
DE (1) DE60140252D1 (en)
DK (1) DK1292680T3 (en)
HU (1) HU228310B1 (en)
IL (2) IL153375A0 (en)
MX (1) MXPA02012602A (en)
NZ (1) NZ523105A (en)
PL (1) PL208113B1 (en)
WO (1) WO2001098361A2 (en)

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Also Published As

Publication number Publication date
US20120045443A1 (en) 2012-02-23
MXPA02012602A (en) 2003-05-14
PL208113B1 (en) 2011-03-31
CA2412494A1 (en) 2001-12-27
AU7142201A (en) 2002-01-02
IL153375A0 (en) 2003-07-06
DK1292680T3 (en) 2010-03-08
EP1292680B1 (en) 2009-10-21
US20070036794A1 (en) 2007-02-15
CN1447857A (en) 2003-10-08
ATE446366T1 (en) 2009-11-15
US20040137513A1 (en) 2004-07-15
WO2001098361A9 (en) 2003-03-06
AU2001271422B2 (en) 2005-12-22
US7384632B2 (en) 2008-06-10
EP1292680A2 (en) 2003-03-19
HUP0300841A2 (en) 2004-06-28
IL153375A (en) 2009-06-15
BR0112272A (en) 2003-05-06
CA2412494C (en) 2012-10-23
CN100519749C (en) 2009-07-29
WO2001098361A3 (en) 2002-05-02
US7615383B2 (en) 2009-11-10
HUP0300841A3 (en) 2005-11-28
KR100823764B1 (en) 2008-04-21
DE60140252D1 (en) 2009-12-03
US20100003261A1 (en) 2010-01-07
KR20030036240A (en) 2003-05-09
WO2001098361A2 (en) 2001-12-27
NZ523105A (en) 2004-07-30
HU228310B1 (en) 2013-03-28
JP2004500873A (en) 2004-01-15

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