PL356465A1 - Sposób wytwarzania 17beta-hydroksy-7alfa-metylo-19-nor-17alfa-pregn-5(10)-en-20-yn-3-onu - Google Patents

Sposób wytwarzania 17beta-hydroksy-7alfa-metylo-19-nor-17alfa-pregn-5(10)-en-20-yn-3-onu

Info

Publication number
PL356465A1
PL356465A1 PL02356465A PL35646502A PL356465A1 PL 356465 A1 PL356465 A1 PL 356465A1 PL 02356465 A PL02356465 A PL 02356465A PL 35646502 A PL35646502 A PL 35646502A PL 356465 A1 PL356465 A1 PL 356465A1
Authority
PL
Poland
Prior art keywords
7alpha
17alpha
17beta
pregn
yne
Prior art date
Application number
PL02356465A
Other languages
English (en)
Inventor
Jacek Martynow
Andrzej Kutner
Wiesław Szelejewski
Wanda Wojciechowska
Hanna Fitak
Original Assignee
ANPHARM Przedsiębiorstwo Farmaceutyczne S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ANPHARM Przedsiębiorstwo Farmaceutyczne S.A. filed Critical ANPHARM Przedsiębiorstwo Farmaceutyczne S.A.
Priority to PL02356465A priority Critical patent/PL356465A1/pl
Priority to AU2003278652A priority patent/AU2003278652A1/en
Priority to EP03770184A priority patent/EP1556407A2/en
Priority to PCT/PL2003/000099 priority patent/WO2004031204A2/en
Priority to US10/530,139 priority patent/US20060111332A1/en
Publication of PL356465A1 publication Critical patent/PL356465A1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0081—Substituted in position 17 alfa and 17 beta
    • C07J1/0088—Substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
    • C07J1/0096—Alkynyl derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/005—Ketals
    • C07J21/006—Ketals at position 3
PL02356465A 2002-10-04 2002-10-04 Sposób wytwarzania 17beta-hydroksy-7alfa-metylo-19-nor-17alfa-pregn-5(10)-en-20-yn-3-onu PL356465A1 (pl)

Priority Applications (5)

Application Number Priority Date Filing Date Title
PL02356465A PL356465A1 (pl) 2002-10-04 2002-10-04 Sposób wytwarzania 17beta-hydroksy-7alfa-metylo-19-nor-17alfa-pregn-5(10)-en-20-yn-3-onu
AU2003278652A AU2003278652A1 (en) 2002-10-04 2003-10-01 Process and intermediates to prepare 17.beta.-hydroxy-7.alfa.-methyl-19-nor-17.alfa.-pregn-5(10)-en-20-yn-3-one
EP03770184A EP1556407A2 (en) 2002-10-04 2003-10-01 Process and intermediates to prepare 17.beta.-hydroxy-7.alfa.-methyl-19-nor-17.alfa.-pregn-5(10)-en-20-yn-3-one
PCT/PL2003/000099 WO2004031204A2 (en) 2002-10-04 2003-10-01 Process and intermediates to prepare 17.beta.-hydroxy-7.alfa.-methyl-19-nor-17.alfa.-pregn-5(10)-en-20-yn-3-one
US10/530,139 US20060111332A1 (en) 2002-10-04 2003-10-01 Process and intermediates to prepare17beta-hydroxy-7alpha-methyl-19-nor-17alpha-pregn -5(10)-en-20-yn-3-one

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL02356465A PL356465A1 (pl) 2002-10-04 2002-10-04 Sposób wytwarzania 17beta-hydroksy-7alfa-metylo-19-nor-17alfa-pregn-5(10)-en-20-yn-3-onu

Publications (1)

Publication Number Publication Date
PL356465A1 true PL356465A1 (pl) 2004-04-05

Family

ID=32065086

Family Applications (1)

Application Number Title Priority Date Filing Date
PL02356465A PL356465A1 (pl) 2002-10-04 2002-10-04 Sposób wytwarzania 17beta-hydroksy-7alfa-metylo-19-nor-17alfa-pregn-5(10)-en-20-yn-3-onu

Country Status (5)

Country Link
US (1) US20060111332A1 (pl)
EP (1) EP1556407A2 (pl)
AU (1) AU2003278652A1 (pl)
PL (1) PL356465A1 (pl)
WO (1) WO2004031204A2 (pl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1861373A2 (en) 2005-03-10 2007-12-05 Mallinckrodt, Inc. Processes for preparing morphinans and intermediates thereof
CN110981930B (zh) * 2019-12-31 2021-04-20 浙江仙居君业药业有限公司 一种替勃龙的合成方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2806030A (en) * 1954-03-20 1957-09-10 Syntex Sa Cyclopentanophenanthrene derivatives and process for the preparation thereof
NL125069C (pl) * 1963-12-24
NL128815C (pl) * 1965-03-16
NL146838B (nl) * 1966-06-24 1975-08-15 Organon Nv Werkwijze voor het bereiden van (delta)5(10)-3- keto-19-norsteroiden.
US3558776A (en) * 1968-06-14 1971-01-26 Upjohn Co Pharmaceutical composition comprising 17alpha - ethynyl -17beta - hydroxy - 7alpha - methyl -5(10)-estrene-3-one
US3904611A (en) * 1972-10-16 1975-09-09 Syntex Corp Preparation of 17' -propadienyl steroids
US4035376A (en) * 1972-10-24 1977-07-12 Janssen Pharmaceutica N.V. Aroyl-substituted phenylacetic acid derivatives
US3928398A (en) * 1973-11-01 1975-12-23 Richardson Merrell Inc Derivatives of 7{60 -methylestr-4-en-3{60 ,17{62 -diol
US4308265A (en) * 1979-10-05 1981-12-29 United States Of America 7α-Methylnorethindrone enanthate and its use in long term suppression of fertility in female mammals
US4252800A (en) * 1979-10-05 1981-02-24 United States Of America 7α-methylnorethindrone enanthate and its use in long term suppression of fertility in female mammals
DE3337179A1 (de) * 1983-10-10 1985-05-23 Schering AG, 1000 Berlin und 4709 Bergkamen Estran- und androstan-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende praeparate
FR2610933B1 (fr) * 1987-02-18 1989-06-09 Roussel Uclaf Nouveaux 19-nor steroides substitues en position 7, leur preparation, leur application comme medicaments, les compositions pharmaceutiques les renfermant
ID28463A (id) * 1998-10-16 2001-05-24 Akzo Nobel Nv KOMPOSISI DENGAN KEMURNIAN TINGGI YANG TERDIRI DARI (7α, 17α)-17-HIDROKSI-7-METIL-19-NOR-17-PREGN-5(10)-EN-20-IN-3-ON

Also Published As

Publication number Publication date
EP1556407A2 (en) 2005-07-27
WO2004031204A2 (en) 2004-04-15
AU2003278652A1 (en) 2004-04-23
AU2003278652A8 (en) 2004-04-23
WO2004031204A3 (en) 2004-07-01
US20060111332A1 (en) 2006-05-25

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Legal Events

Date Code Title Description
DISC Decisions on discontinuance of the proceedings (taken after the publication of the particulars of the applications)