PL341396A1 - Modified syntheses of diacetoxycephalosporin c (daocs) and its roentgenographic structure - Google Patents

Modified syntheses of diacetoxycephalosporin c (daocs) and its roentgenographic structure

Info

Publication number
PL341396A1
PL341396A1 PL98341396A PL34139698A PL341396A1 PL 341396 A1 PL341396 A1 PL 341396A1 PL 98341396 A PL98341396 A PL 98341396A PL 34139698 A PL34139698 A PL 34139698A PL 341396 A1 PL341396 A1 PL 341396A1
Authority
PL
Poland
Prior art keywords
diacetoxycephalosporin
daocs
roentgenographic
syntheses
modified
Prior art date
Application number
PL98341396A
Inventor
Christopher Joseph Schofield
Jack Edward Baldwin
Peter L Roach
Matthew D Lloyd
Karl Harlos
Inger Andersson
Janos Hajdu
Van Scheltinga Anke Terwisscha
Karin Valegard
S Ramaswamy
Original Assignee
Isis Innovation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9727370.0A external-priority patent/GB9727370D0/en
Priority claimed from GBGB9813644.3A external-priority patent/GB9813644D0/en
Application filed by Isis Innovation filed Critical Isis Innovation
Publication of PL341396A1 publication Critical patent/PL341396A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Cephalosporin Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL98341396A 1997-12-24 1998-12-24 Modified syntheses of diacetoxycephalosporin c (daocs) and its roentgenographic structure PL341396A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9727370.0A GB9727370D0 (en) 1997-12-24 1997-12-24 Processed based on the structure of deacetoxycephalosporin c synthase
GBGB9813644.3A GB9813644D0 (en) 1998-06-24 1998-06-24 Structure of a cephalosporin synthase
PCT/GB1998/003860 WO1999033994A1 (en) 1997-12-24 1998-12-24 Modified deacetoxycephalosporin c synthase (daocs) and x-ray structure

Publications (1)

Publication Number Publication Date
PL341396A1 true PL341396A1 (en) 2001-04-09

Family

ID=26312856

Family Applications (1)

Application Number Title Priority Date Filing Date
PL98341396A PL341396A1 (en) 1997-12-24 1998-12-24 Modified syntheses of diacetoxycephalosporin c (daocs) and its roentgenographic structure

Country Status (8)

Country Link
EP (1) EP1047785A1 (en)
JP (1) JP2002500015A (en)
CN (1) CN1284997A (en)
AU (1) AU1772099A (en)
CA (1) CA2316401A1 (en)
PL (1) PL341396A1 (en)
SK (1) SK9762000A3 (en)
WO (1) WO1999033994A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0011185D0 (en) * 2000-05-09 2000-06-28 Synpac Pharmaceuticals Limited Protein
US6699699B2 (en) * 2002-03-26 2004-03-02 Synmax Biochemical Co., Ltd. Mutated penicillin expandases
US9404139B2 (en) * 2012-01-10 2016-08-02 Orchid Chemicals & Pharmaceuticals Limited Mutated cephalosporin hydroxylase and its application in deacetylcephalosporanic acid synthesis
CN114958877B (en) * 2022-06-14 2024-02-20 河南省健康元生物医药研究院有限公司 Deacetylated oxo cephalosporin C synthetase mutant, encoding gene and application thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5082772A (en) * 1988-10-24 1992-01-21 Eli Lilly And Company Process for preparing deacetylcephalosporin c
US5318896A (en) * 1991-09-11 1994-06-07 Merck & Co., Inc. Recombinant expandase bioprocess for preparing 7-aminodesacetoxy cephalosporanic acid (7-ADCA)
WO1997020053A2 (en) * 1995-11-27 1997-06-05 Gist-Brocades B.V. Improved process for the production of semi-synthetic cephalosporins via expandase activity on penicillin g
GB9621486D0 (en) * 1996-10-15 1996-12-04 Isis Innovation Oxygenase enzymes & method

Also Published As

Publication number Publication date
SK9762000A3 (en) 2001-02-12
JP2002500015A (en) 2002-01-08
CN1284997A (en) 2001-02-21
AU1772099A (en) 1999-07-19
CA2316401A1 (en) 1999-07-08
EP1047785A1 (en) 2000-11-02
WO1999033994A1 (en) 1999-07-08

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