PL3117012T3 - Sposoby monitorowania terapii immunosupresyjnych u biorcy przeszczepu - Google Patents

Sposoby monitorowania terapii immunosupresyjnych u biorcy przeszczepu

Info

Publication number
PL3117012T3
PL3117012T3 PL15761889T PL15761889T PL3117012T3 PL 3117012 T3 PL3117012 T3 PL 3117012T3 PL 15761889 T PL15761889 T PL 15761889T PL 15761889 T PL15761889 T PL 15761889T PL 3117012 T3 PL3117012 T3 PL 3117012T3
Authority
PL
Poland
Prior art keywords
methods
transplant recipient
immunosuppressive therapies
monitoring
monitoring immunosuppressive
Prior art date
Application number
PL15761889T
Other languages
English (en)
Inventor
Robert Woodward
Marica Grskovic
Jim Yee
Mitch NELLES
David HILLER
Original Assignee
Caredx, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=54072508&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL3117012(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Caredx, Inc. filed Critical Caredx, Inc.
Publication of PL3117012T3 publication Critical patent/PL3117012T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/30ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL15761889T 2014-03-14 2015-03-13 Sposoby monitorowania terapii immunosupresyjnych u biorcy przeszczepu PL3117012T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461953582P 2014-03-14 2014-03-14
PCT/US2015/020603 WO2015138997A1 (en) 2014-03-14 2015-03-13 Methods of monitoring immunosuppressive therapies in a transplant recipient
EP15761889.3A EP3117012B1 (en) 2014-03-14 2015-03-13 Methods of monitoring immunosuppressive therapies in a transplant recipient

Publications (1)

Publication Number Publication Date
PL3117012T3 true PL3117012T3 (pl) 2019-08-30

Family

ID=54072508

Family Applications (1)

Application Number Title Priority Date Filing Date
PL15761889T PL3117012T3 (pl) 2014-03-14 2015-03-13 Sposoby monitorowania terapii immunosupresyjnych u biorcy przeszczepu

Country Status (15)

Country Link
US (9) US11767559B2 (pl)
EP (1) EP3117012B1 (pl)
CN (2) CN106536752B (pl)
AU (3) AU2015229083B2 (pl)
BR (1) BR112016021038B1 (pl)
CA (1) CA2970916A1 (pl)
DK (1) DK3117012T3 (pl)
ES (1) ES2726650T3 (pl)
HR (1) HRP20190759T1 (pl)
HU (1) HUE043288T2 (pl)
PL (1) PL3117012T3 (pl)
PT (1) PT3117012T (pl)
SI (1) SI3117012T1 (pl)
TR (1) TR201907106T4 (pl)
WO (1) WO2015138997A1 (pl)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11111544B2 (en) 2005-07-29 2021-09-07 Natera, Inc. System and method for cleaning noisy genetic data and determining chromosome copy number
US9424392B2 (en) 2005-11-26 2016-08-23 Natera, Inc. System and method for cleaning noisy genetic data from target individuals using genetic data from genetically related individuals
US11111543B2 (en) 2005-07-29 2021-09-07 Natera, Inc. System and method for cleaning noisy genetic data and determining chromosome copy number
WO2011041485A1 (en) 2009-09-30 2011-04-07 Gene Security Network, Inc. Methods for non-invasive prenatal ploidy calling
US20190284623A1 (en) * 2010-05-18 2019-09-19 Natera, Inc. Methods for non-invasive prenatal ploidy calling
US11408031B2 (en) 2010-05-18 2022-08-09 Natera, Inc. Methods for non-invasive prenatal paternity testing
US20190010543A1 (en) 2010-05-18 2019-01-10 Natera, Inc. Methods for simultaneous amplification of target loci
US10316362B2 (en) 2010-05-18 2019-06-11 Natera, Inc. Methods for simultaneous amplification of target loci
US11326208B2 (en) 2010-05-18 2022-05-10 Natera, Inc. Methods for nested PCR amplification of cell-free DNA
US9677118B2 (en) 2014-04-21 2017-06-13 Natera, Inc. Methods for simultaneous amplification of target loci
EP2854057B1 (en) 2010-05-18 2018-03-07 Natera, Inc. Methods for non-invasive pre-natal ploidy calling
US11322224B2 (en) 2010-05-18 2022-05-03 Natera, Inc. Methods for non-invasive prenatal ploidy calling
US11332785B2 (en) * 2010-05-18 2022-05-17 Natera, Inc. Methods for non-invasive prenatal ploidy calling
US11332793B2 (en) 2010-05-18 2022-05-17 Natera, Inc. Methods for simultaneous amplification of target loci
US11339429B2 (en) * 2010-05-18 2022-05-24 Natera, Inc. Methods for non-invasive prenatal ploidy calling
US11939634B2 (en) 2010-05-18 2024-03-26 Natera, Inc. Methods for simultaneous amplification of target loci
AU2011348100B2 (en) 2010-12-22 2016-08-25 Natera, Inc. Methods for non-invasive prenatal paternity testing
LT3004388T (lt) 2013-05-29 2019-01-25 Chronix Biomedical Donoro ne ląstelinės dnr aptikimas ir jos kiekio nustatymas organo transplantanto recipientų apytakoje
US10577655B2 (en) 2013-09-27 2020-03-03 Natera, Inc. Cell free DNA diagnostic testing standards
PL3117012T3 (pl) * 2014-03-14 2019-08-30 Caredx, Inc. Sposoby monitorowania terapii immunosupresyjnych u biorcy przeszczepu
CN113774132A (zh) 2014-04-21 2021-12-10 纳特拉公司 检测染色体片段中的突变和倍性
EP3164503A1 (en) 2014-07-03 2017-05-10 Multiplicom NV Methods for non-invasive detection of transplant health or rejection
WO2016183106A1 (en) 2015-05-11 2016-11-17 Natera, Inc. Methods and compositions for determining ploidy
CN106544407B (zh) * 2015-09-18 2019-11-08 广州华大基因医学检验所有限公司 确定受体cfDNA样本中供体来源cfDNA比例的方法
CN105483123B (zh) * 2015-11-23 2019-02-22 元码基因科技(北京)股份有限公司 遗传标记组合、个体基因身份证及其用途
US11485996B2 (en) 2016-10-04 2022-11-01 Natera, Inc. Methods for characterizing copy number variation using proximity-litigation sequencing
EP3535413A1 (en) * 2016-11-02 2019-09-11 The Medical College of Wisconsin, Inc. Methods for assessing risk using total and specific cell-free dna
CN106520982B (zh) * 2016-12-05 2019-11-08 中国人民解放军军事医学科学院放射与辐射医学研究所 一种用于身份鉴定的复合分型系统
US10011870B2 (en) 2016-12-07 2018-07-03 Natera, Inc. Compositions and methods for identifying nucleic acid molecules
CN107058562B (zh) * 2017-05-17 2018-04-10 成都仕康美生物科技有限公司 Snp位点的应用及其检测试剂盒
WO2018237075A1 (en) 2017-06-20 2018-12-27 The Medical College Of Wisconsin, Inc. ASSESSING THE RISK OF GRAFT COMPLICATION WITH TOTAL ACELLULAR DNA
CN110945144A (zh) * 2017-06-20 2020-03-31 威斯康星州立大学医学院 利用无细胞dna的移植患者监测
SG11202005474RA (en) * 2017-12-15 2020-07-29 Acrannolife Genomics Pvt Ltd A non-invasive method for monitoring transplanted organ status in organ-transplant recipients
CN107937571B (zh) * 2018-01-16 2021-12-07 良培基因生物科技(武汉)有限公司 一种基于信息snp集及其引物的核酸质谱亲权鉴定方法
EP3517629A1 (en) 2018-01-30 2019-07-31 Myway Genetics S.r.L. Use of cfdna fragments as biomarkers in patients after organ transplantation
US11525159B2 (en) 2018-07-03 2022-12-13 Natera, Inc. Methods for detection of donor-derived cell-free DNA
EP3847280A1 (en) * 2018-09-07 2021-07-14 Sequenom, Inc. Methods, and systems to detect transplant rejection
WO2020076957A1 (en) * 2018-10-09 2020-04-16 Tai Diagnostics, Inc. Cell lysis assay for cell-free dna analysis
US20220073989A1 (en) * 2018-12-20 2022-03-10 The Regents Of The University Of California Optimizing Detection of Transplant Injury by Donor-Derived Cell-Free DNA
WO2020172164A1 (en) * 2019-02-19 2020-08-27 Sequenom, Inc. Compositions, methods, and systems to detect hematopoietic stem cell transplantation status
US11931674B2 (en) 2019-04-04 2024-03-19 Natera, Inc. Materials and methods for processing blood samples
EP4106872A4 (en) * 2020-03-06 2024-04-10 Denovo Biopharma Llc COMPOSITIONS AND METHODS FOR EVALUATING THE EFFICACY OF NEUROTRANSMITTER TRANSPORTER INHIBITORS
US20210395835A1 (en) * 2020-06-19 2021-12-23 Caredx, Inc. Methods for monitoring allogeneic cells
CN113061666A (zh) * 2020-12-30 2021-07-02 中南大学湘雅二医院 肝移植后巨细胞病毒的检测方法、应用及系统
CA3226436A1 (en) * 2021-07-23 2023-01-26 Megan E. Mcnamara Use of circulating cell-free methylated dna to detect tissue damage
US20230348985A1 (en) * 2022-03-21 2023-11-02 CarexDx, Inc. Methods for non-invasively monitoring organ health in cross-species transplantation

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE39920E1 (en) 1997-05-30 2007-11-13 Xenomics, Inc. Methods for detection of nucleic acid sequences in urine
US6132997A (en) 1999-05-28 2000-10-17 Agilent Technologies Method for linear mRNA amplification
ES2532153T3 (es) * 2008-07-18 2015-03-24 Trovagene, Inc. Métodos para la detección de secuencias de ácidos nucleicos "ultracortos" basados en PCR
JP2013509883A (ja) 2009-11-06 2013-03-21 ザ ボード オブ トラスティーズ オブ ザ リーランド スタンフォード ジュニア ユニバーシティ 臓器移植患者における移植片拒絶反応の非侵襲的診断方法
US20120034603A1 (en) * 2010-08-06 2012-02-09 Tandem Diagnostics, Inc. Ligation-based detection of genetic variants
US10131947B2 (en) * 2011-01-25 2018-11-20 Ariosa Diagnostics, Inc. Noninvasive detection of fetal aneuploidy in egg donor pregnancies
CN102618626B (zh) * 2011-01-30 2014-05-14 杭州优思达生物技术有限公司 一种快速单核苷酸多态性的检测方法及试剂盒
US20130024127A1 (en) 2011-07-19 2013-01-24 John Stuelpnagel Determination of source contributions using binomial probability calculations
US20150211070A1 (en) * 2011-09-22 2015-07-30 Immu-Metrix, Llc Compositions and methods for analyzing heterogeneous samples
AU2012321053B2 (en) 2011-10-07 2018-04-19 Murdoch Childrens Research Institute Diagnostic assay for tissue transplantation status
CN103374518B (zh) * 2012-04-12 2018-03-27 维里纳塔健康公司 拷贝数变异的检测和分类
US10385396B2 (en) 2012-04-19 2019-08-20 The Medical College Of Wisconsin, Inc. Highly sensitive surveillance using detection of cell free DNA
LT3004388T (lt) * 2013-05-29 2019-01-25 Chronix Biomedical Donoro ne ląstelinės dnr aptikimas ir jos kiekio nustatymas organo transplantanto recipientų apytakoje
PL3117012T3 (pl) 2014-03-14 2019-08-30 Caredx, Inc. Sposoby monitorowania terapii immunosupresyjnych u biorcy przeszczepu
JP2020515278A (ja) 2017-04-04 2020-05-28 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー ドナー遺伝子型の非存在下での移植由来循環セルフリーdnaの定量化
CN110770839A (zh) 2017-06-20 2020-02-07 伊鲁米那股份有限公司 来自未知基因型贡献者的dna混合物的精确计算分解的方法
WO2018236911A1 (en) 2017-06-20 2018-12-27 Illumina, Inc. METHODS AND SYSTEMS FOR DECOMPOSING AND QUANTIFYING DNA MIXTURES FROM MULTIPLE CONTRIBUTORS HAVING KNOWN OR UNKNOWN GENOTYPES
WO2020172164A1 (en) 2019-02-19 2020-08-27 Sequenom, Inc. Compositions, methods, and systems to detect hematopoietic stem cell transplantation status
US20210395835A1 (en) 2020-06-19 2021-12-23 Caredx, Inc. Methods for monitoring allogeneic cells

Also Published As

Publication number Publication date
AU2015229083A1 (en) 2016-09-08
AU2021204489B2 (en) 2023-04-27
EP3117012B1 (en) 2019-02-20
EP3117012A1 (en) 2017-01-18
AU2021204489A1 (en) 2021-07-29
US20230399694A1 (en) 2023-12-14
US20230407394A1 (en) 2023-12-21
CA2970916A1 (en) 2015-09-17
US20230399695A1 (en) 2023-12-14
AU2023208145A1 (en) 2023-08-17
US20230407395A1 (en) 2023-12-21
SI3117012T1 (sl) 2019-07-31
HUE043288T2 (hu) 2019-08-28
EP3117012A4 (en) 2017-08-30
ES2726650T3 (es) 2019-10-08
BR112016021038A2 (pt) 2017-08-15
CN106536752B (zh) 2021-08-06
US20230399696A1 (en) 2023-12-14
US11767559B2 (en) 2023-09-26
CN106536752A (zh) 2017-03-22
TR201907106T4 (tr) 2019-06-21
CN113528645A (zh) 2021-10-22
HRP20190759T1 (hr) 2019-06-14
US20230407392A1 (en) 2023-12-21
WO2015138997A1 (en) 2015-09-17
US20230407396A1 (en) 2023-12-21
AU2015229083B2 (en) 2021-06-17
DK3117012T3 (da) 2019-05-13
US20160145682A1 (en) 2016-05-26
US20230407393A1 (en) 2023-12-21
BR112016021038B1 (pt) 2023-12-12
PT3117012T (pt) 2019-05-30

Similar Documents

Publication Publication Date Title
HUE043288T2 (hu) Eljárások immunszuppresszív terápiák monitorozására transzplantátum recipiensben
IL276593B (en) Improved methods for producing adoptive cell therapies
PL3182503T3 (pl) Pakiet akumulatorowy
IL248761B (en) Unique inorganic particles
GB201407805D0 (en) Battery condition determination
GB201413086D0 (en) Methods
HK1231632A1 (zh) 電池
HK1213974A1 (zh) 儲藏箱以及冰箱
PL3145818T3 (pl) Zespół oraz sposób do magazynowania pojemników
HK1223075A1 (zh) 收納箱
SG11201704473WA (en) New methods and uses
GB201401197D0 (en) Battery pack
GB201402666D0 (en) Sequestration of lithium
HUE045669T2 (hu) A softbitek tárolására szolgáló technika
AP00770S1 (en) Gas container
GB201411985D0 (en) Battery
GB201408091D0 (en) Methods and uses
HK1202220A2 (en) Rechargeable battery
GB201415685D0 (en) Methods
SG10201403640XA (en) Stem cells
GB201420088D0 (en) Battery modules and methods for their manufacture
AU362175S (en) Battery pack
GB201413395D0 (en) Cell separation methods
GB201416073D0 (en) Methods and uses
GB201406991D0 (en) Methods