PL3007732T3 - Dwufunkcyjne środki chelatujące oparte na szkielecie 1,4-diazepiny (DAZA) do nieinwazyjnego obrazowania molekularnego - Google Patents

Dwufunkcyjne środki chelatujące oparte na szkielecie 1,4-diazepiny (DAZA) do nieinwazyjnego obrazowania molekularnego

Info

Publication number
PL3007732T3
PL3007732T3 PL14724082T PL14724082T PL3007732T3 PL 3007732 T3 PL3007732 T3 PL 3007732T3 PL 14724082 T PL14724082 T PL 14724082T PL 14724082 T PL14724082 T PL 14724082T PL 3007732 T3 PL3007732 T3 PL 3007732T3
Authority
PL
Poland
Prior art keywords
daza
chelating agents
molecular imaging
agents based
bifunctional chelating
Prior art date
Application number
PL14724082T
Other languages
English (en)
Inventor
Frank RÖSCH
Bradley Peter WALDRON
David Parker
Original Assignee
Johannes-Gutenberg-Universität Mainz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Johannes-Gutenberg-Universität Mainz filed Critical Johannes-Gutenberg-Universität Mainz
Publication of PL3007732T3 publication Critical patent/PL3007732T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0482—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group chelates from cyclic ligands, e.g. DOTA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0489—Phosphates or phosphonates, e.g. bone-seeking phosphonates

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
PL14724082T 2013-06-11 2014-05-14 Dwufunkcyjne środki chelatujące oparte na szkielecie 1,4-diazepiny (DAZA) do nieinwazyjnego obrazowania molekularnego PL3007732T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102013106066.8A DE102013106066A1 (de) 2013-06-11 2013-06-11 Bifunktionelle Chelatbildner auf der Basis des 1,4-Diazepin-Gerüsts (DAZA) für die nicht invasive molekulare Bilddarstellung
EP14724082.4A EP3007732B1 (en) 2013-06-11 2014-05-14 Bifunctional chelating agents based on the 1,4-diazepine scaffold (daza) for non-invasive molecular imaging
PCT/EP2014/059874 WO2014198478A2 (en) 2013-06-11 2014-05-14 Bifunctional chelating agents based on the 1,4-diazepine scaffold (daza) for non-invasive molecular imaging

Publications (1)

Publication Number Publication Date
PL3007732T3 true PL3007732T3 (pl) 2019-03-29

Family

ID=52009005

Family Applications (1)

Application Number Title Priority Date Filing Date
PL14724082T PL3007732T3 (pl) 2013-06-11 2014-05-14 Dwufunkcyjne środki chelatujące oparte na szkielecie 1,4-diazepiny (DAZA) do nieinwazyjnego obrazowania molekularnego

Country Status (5)

Country Link
US (1) US10130722B2 (pl)
EP (1) EP3007732B1 (pl)
DE (1) DE102013106066A1 (pl)
PL (1) PL3007732T3 (pl)
WO (1) WO2014198478A2 (pl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10729669B2 (en) 2015-07-28 2020-08-04 University Of Iowa Research Foundation Compositions and methods for treating cancer
WO2017223565A1 (en) * 2016-06-24 2017-12-28 University Of Iowa Research Foundation Compositions and methods of treating melanoma
CA3045466A1 (en) 2016-12-01 2018-06-07 Regeneron Pharmaceuticals, Inc. Radiolabeled anti-pd-l1 antibodies for immuno-pet imaging
DE102017129405A1 (de) 2017-12-11 2019-06-13 Universitätsklinikum Jena Neue DAZA-Chelatoren als Liganden in der Leberbildgebung
US11529335B2 (en) 2020-07-31 2022-12-20 University Of Iowa Research Foundation Compositions and methods for treating cancer

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20011518A1 (it) 2001-07-17 2003-01-17 Bracco Imaging Spa Leganti azotati multidentati capaci di complessare ioni metallici e loro uso in diagnostica e in terapia
US7893223B2 (en) 2001-07-17 2011-02-22 Bracco Imaging S.P.A. Multidentate AZA ligands able to complex metal ions and the use thereof in diagnostics and therapy
EP1964846A1 (en) * 2007-02-27 2008-09-03 Bracco Imaging, S.P.A. Process for the preparation of contrast agents

Also Published As

Publication number Publication date
US10130722B2 (en) 2018-11-20
WO2014198478A3 (en) 2015-02-05
EP3007732A2 (en) 2016-04-20
DE102013106066A1 (de) 2014-12-11
EP3007732B1 (en) 2018-09-26
WO2014198478A2 (en) 2014-12-18
US20160136309A1 (en) 2016-05-19

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