PL2970260T3 - Imidazo[4,5-c]pyridine and pyrrolo[2,3-c]pyridine derivatives as ssao inhibitors - Google Patents

Imidazo[4,5-c]pyridine and pyrrolo[2,3-c]pyridine derivatives as ssao inhibitors

Info

Publication number
PL2970260T3
PL2970260T3 PL14711578T PL14711578T PL2970260T3 PL 2970260 T3 PL2970260 T3 PL 2970260T3 PL 14711578 T PL14711578 T PL 14711578T PL 14711578 T PL14711578 T PL 14711578T PL 2970260 T3 PL2970260 T3 PL 2970260T3
Authority
PL
Poland
Prior art keywords
pyridine
pyrrolo
imidazo
ssao inhibitors
derivatives
Prior art date
Application number
PL14711578T
Other languages
Polish (pl)
Inventor
Max Espensen
Lee Patient
David Evans
Iain Simpson
Edward Savory
Original Assignee
Proximagen Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Proximagen Llc filed Critical Proximagen Llc
Publication of PL2970260T3 publication Critical patent/PL2970260T3/en

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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
    • C07C53/15—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen containing halogen
    • C07C53/16—Halogenated acetic acids
    • C07C53/18—Halogenated acetic acids containing fluorine
PL14711578T 2013-03-13 2014-03-13 Imidazo[4,5-c]pyridine and pyrrolo[2,3-c]pyridine derivatives as ssao inhibitors PL2970260T3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1304526.5A GB201304526D0 (en) 2013-03-13 2013-03-13 New compounds
EP14711578.6A EP2970260B1 (en) 2013-03-13 2014-03-13 Imidazo[4,5-c]pyridine and pyrrolo[2,3-c]pyridine derivatives as ssao inhibitors
PCT/GB2014/050765 WO2014140592A1 (en) 2013-03-13 2014-03-13 Imidazo[4,5-c]pyridine and pyrrolo[2,3-c]pyridine derivatives as ssao inhibitors

Publications (1)

Publication Number Publication Date
PL2970260T3 true PL2970260T3 (en) 2019-10-31

Family

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PL14711578T PL2970260T3 (en) 2013-03-13 2014-03-13 Imidazo[4,5-c]pyridine and pyrrolo[2,3-c]pyridine derivatives as ssao inhibitors

Country Status (22)

Country Link
US (9) US9676769B2 (en)
EP (1) EP2970260B1 (en)
JP (2) JP6334577B2 (en)
KR (1) KR102187811B1 (en)
CN (1) CN105189494B (en)
AU (1) AU2014229763B2 (en)
BR (1) BR112015022011B1 (en)
CA (1) CA2902121C (en)
DK (1) DK2970260T3 (en)
EA (1) EA034066B1 (en)
ES (1) ES2727977T3 (en)
GB (1) GB201304526D0 (en)
HK (1) HK1214249A1 (en)
HU (1) HUE043456T2 (en)
MX (1) MX368149B (en)
NZ (1) NZ711229A (en)
PL (1) PL2970260T3 (en)
PT (1) PT2970260T (en)
SG (2) SG10201710801WA (en)
TR (1) TR201907590T4 (en)
WO (1) WO2014140592A1 (en)
ZA (1) ZA201506182B (en)

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SG10201710801WA (en) 2018-02-27
US20200347059A1 (en) 2020-11-05
CA2902121C (en) 2022-09-20
JP6334577B2 (en) 2018-05-30
PT2970260T (en) 2019-06-04
MX2015012010A (en) 2016-04-07
KR20150139832A (en) 2015-12-14
NZ711229A (en) 2020-07-31
US9951068B2 (en) 2018-04-24
US20200262835A1 (en) 2020-08-20
US9428498B2 (en) 2016-08-30
GB201304526D0 (en) 2013-04-24
HK1214249A1 (en) 2016-07-22
ES2727977T3 (en) 2019-10-21
US20140275040A1 (en) 2014-09-18
JP6705862B2 (en) 2020-06-03
BR112015022011A2 (en) 2017-07-18
US10968223B2 (en) 2021-04-06
EP2970260A1 (en) 2016-01-20
WO2014140592A1 (en) 2014-09-18
TR201907590T4 (en) 2019-06-21
US10766897B2 (en) 2020-09-08
AU2014229763B2 (en) 2017-10-19
AU2014229763A8 (en) 2015-09-24
US20160326172A1 (en) 2016-11-10
CN105189494B (en) 2017-04-26
AU2014229763A1 (en) 2015-09-10
US20160046622A1 (en) 2016-02-18
US9676769B2 (en) 2017-06-13
MX368149B (en) 2019-09-20
SG11201507182TA (en) 2015-10-29
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