PL2911671T3 - Pirazolopirydazyny oraz sposoby leczenia zwyrodnieniowych chorób siatkówki i utraty słuchu związanych z zespołem ushera - Google Patents

Pirazolopirydazyny oraz sposoby leczenia zwyrodnieniowych chorób siatkówki i utraty słuchu związanych z zespołem ushera

Info

Publication number
PL2911671T3
PL2911671T3 PL13848995T PL13848995T PL2911671T3 PL 2911671 T3 PL2911671 T3 PL 2911671T3 PL 13848995 T PL13848995 T PL 13848995T PL 13848995 T PL13848995 T PL 13848995T PL 2911671 T3 PL2911671 T3 PL 2911671T3
Authority
PL
Poland
Prior art keywords
pyrazolopyridazines
methods
hearing loss
degenerative diseases
loss associated
Prior art date
Application number
PL13848995T
Other languages
English (en)
Inventor
Roland Werner BURLI
William Rameshchandra Krishna ESMIEU
Christopher James Lock
Karine Fabienne MALAGU
Andrew Pate Owens
William Edward HARTE
Original Assignee
Usher Iii Initiative, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Usher Iii Initiative, Inc. filed Critical Usher Iii Initiative, Inc.
Publication of PL2911671T3 publication Critical patent/PL2911671T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
PL13848995T 2012-10-25 2013-10-25 Pirazolopirydazyny oraz sposoby leczenia zwyrodnieniowych chorób siatkówki i utraty słuchu związanych z zespołem ushera PL2911671T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201261718611P 2012-10-25 2012-10-25
US201361775402P 2013-03-08 2013-03-08
EP13848995.0A EP2911671B1 (en) 2012-10-25 2013-10-25 Pyrazolopyridazines and methods for treating retinal-degenerative diseases and hearing loss associated with usher syndrome
PCT/US2013/066939 WO2014066836A1 (en) 2012-10-25 2013-10-25 Pyrazolopyridazines and methods for treating retinal-degenerative diseases and hearing loss associated with usher syndrome

Publications (1)

Publication Number Publication Date
PL2911671T3 true PL2911671T3 (pl) 2018-11-30

Family

ID=50545356

Family Applications (1)

Application Number Title Priority Date Filing Date
PL13848995T PL2911671T3 (pl) 2012-10-25 2013-10-25 Pirazolopirydazyny oraz sposoby leczenia zwyrodnieniowych chorób siatkówki i utraty słuchu związanych z zespołem ushera

Country Status (11)

Country Link
EP (1) EP2911671B1 (pl)
JP (1) JP6291502B2 (pl)
AU (1) AU2013334139B2 (pl)
CA (1) CA2889494C (pl)
ES (1) ES2687854T3 (pl)
HK (1) HK1214180A1 (pl)
HU (1) HUE039970T2 (pl)
IL (1) IL238288B (pl)
PL (1) PL2911671T3 (pl)
WO (1) WO2014066836A1 (pl)
ZA (1) ZA201502655B (pl)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2701510B1 (en) 2011-04-25 2017-02-15 Usher III Initiative Pyrazolopyridazines and methods for treating retinal-degenerative diseases and hearing loss associated with usher syndrome
US9227976B2 (en) 2012-10-25 2016-01-05 Usher Iii Initiative, Inc. Pyrazolopyridazines and methods for treating retinal-degenerative diseases and hearing loss associated with usher syndrome
JP6290910B2 (ja) * 2012-10-25 2018-03-07 アッシャー・サード・イニシアティブ・インコーポレイテッド ピラゾロピリダジンならびに網膜変性疾患およびアッシャー症候群に伴う聴力損失を処置するための方法
WO2017045955A1 (en) * 2015-09-14 2017-03-23 Basf Se Heterobicyclic compounds
JP7399870B2 (ja) 2018-03-27 2023-12-18 ピーティーシー セラピューティクス, インコーポレイテッド ハンチントン病を処置するための化合物
JP7421507B2 (ja) * 2018-06-27 2024-01-24 ピーティーシー セラピューティクス, インコーポレイテッド ハンチントン病を処置するためのヘテロ環式およびヘテロアリール化合物
WO2020161208A1 (en) 2019-02-06 2020-08-13 Syngenta Crop Protection Ag Herbicidal fused pyridazine compounds
WO2020161209A1 (en) 2019-02-06 2020-08-13 Syngenta Crop Protection Ag Herbicidal fused pyridazine compounds
WO2023139091A1 (en) * 2022-01-19 2023-07-27 INSERM (Institut National de la Santé et de la Recherche Médicale) Geralexin and uses thereof for the treatment of retinal degenerative diseases

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0206723D0 (en) * 2002-03-21 2002-05-01 Glaxo Group Ltd Novel compounds
US20090306045A1 (en) * 2005-12-22 2009-12-10 Ira Mellman Inhibition of Glycogen Synthase Kinase and Methods of Treating Autoimmune or Immune Inflammatory Disease
US20100331297A1 (en) * 2007-11-07 2010-12-30 Foldrx Pharmaceuticals, Inc. Modulation of protein trafficking
EP2701510B1 (en) * 2011-04-25 2017-02-15 Usher III Initiative Pyrazolopyridazines and methods for treating retinal-degenerative diseases and hearing loss associated with usher syndrome
JP6290910B2 (ja) * 2012-10-25 2018-03-07 アッシャー・サード・イニシアティブ・インコーポレイテッド ピラゾロピリダジンならびに網膜変性疾患およびアッシャー症候群に伴う聴力損失を処置するための方法

Also Published As

Publication number Publication date
IL238288B (en) 2018-04-30
EP2911671A4 (en) 2016-09-14
JP6291502B2 (ja) 2018-03-14
EP2911671A1 (en) 2015-09-02
AU2013334139A1 (en) 2015-04-30
AU2013334139B2 (en) 2017-08-03
IL238288A0 (en) 2015-06-30
WO2014066836A1 (en) 2014-05-01
HUE039970T2 (hu) 2019-02-28
EP2911671B1 (en) 2018-06-27
CA2889494A1 (en) 2014-05-01
HK1214180A1 (zh) 2016-07-22
ES2687854T3 (es) 2018-10-29
CA2889494C (en) 2018-12-18
ZA201502655B (en) 2017-11-29
JP2015535257A (ja) 2015-12-10

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