PL2888243T3 - Acrylamide compounds as histamine h3 receptor ligands - Google Patents
Acrylamide compounds as histamine h3 receptor ligandsInfo
- Publication number
- PL2888243T3 PL2888243T3 PL12844650T PL12844650T PL2888243T3 PL 2888243 T3 PL2888243 T3 PL 2888243T3 PL 12844650 T PL12844650 T PL 12844650T PL 12844650 T PL12844650 T PL 12844650T PL 2888243 T3 PL2888243 T3 PL 2888243T3
- Authority
- PL
- Poland
- Prior art keywords
- histamine
- receptor ligands
- acrylamide compounds
- acrylamide
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C55/00—Saturated compounds having more than one carboxyl group bound to acyclic carbon atoms
- C07C55/02—Dicarboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN3464CH2012 | 2012-08-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2888243T3 true PL2888243T3 (en) | 2017-01-31 |
Family
ID=54187093
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL12844650T PL2888243T3 (en) | 2012-08-23 | 2012-12-05 | Acrylamide compounds as histamine h3 receptor ligands |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US9328092B2 (en) |
| EP (1) | EP2888243B1 (en) |
| JP (1) | JP5981654B2 (en) |
| KR (1) | KR101707343B1 (en) |
| CN (1) | CN104540812B (en) |
| AP (1) | AP2014008139A0 (en) |
| AU (1) | AU2012388383C1 (en) |
| BR (1) | BR112015001524B1 (en) |
| CA (1) | CA2878217C (en) |
| CY (1) | CY1118035T1 (en) |
| DK (1) | DK2888243T3 (en) |
| EA (1) | EA025136B1 (en) |
| ES (1) | ES2592819T3 (en) |
| HK (1) | HK1204620A1 (en) |
| HR (1) | HRP20161167T1 (en) |
| HU (1) | HUE030901T2 (en) |
| IL (1) | IL236437A (en) |
| LT (1) | LT2888243T (en) |
| ME (1) | ME02519B (en) |
| MX (1) | MX360001B (en) |
| PL (1) | PL2888243T3 (en) |
| PT (1) | PT2888243T (en) |
| RS (1) | RS55158B1 (en) |
| SG (1) | SG11201408423XA (en) |
| SI (1) | SI2888243T1 (en) |
| SM (1) | SMT201600336B (en) |
| WO (1) | WO2014030170A1 (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11313246B2 (en) | 2016-11-30 | 2022-04-26 | General Electric Company | Gas turbine engine wash system |
| WO2022113008A1 (en) | 2020-11-27 | 2022-06-02 | Richter Gedeon Nyrt. | Histamine h3 receptor antagonists/inverse agonists for the treatment of autism spectrum disorder |
| CN116693470A (en) * | 2022-03-02 | 2023-09-05 | 杭州百诚医药科技股份有限公司 | Histamine H3 receptor inhibitor and medical application thereof |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2004247320A1 (en) * | 2003-06-12 | 2004-12-23 | Novo Nordisk A/S | 1-aryl-4-(aryloxycarbonyl)-piperazine derivatives for use as inhibitors of hormone sensitive lipase |
| US8008301B2 (en) | 2004-04-01 | 2011-08-30 | Eli Lilly And Company | Histamine H3 receptor agents, preparation and therapeutic uses |
| RU2387638C2 (en) * | 2004-06-02 | 2010-04-27 | Ф.Хофманн-ля Рош АГ | Naphthalene derivatives suitable for use as ligands of histamine 3 receptors |
| EP1761519B1 (en) | 2004-06-21 | 2008-05-07 | F.Hoffmann-La Roche Ag | Indole derivatives as histamine receptor antagonists |
| MX2007002274A (en) | 2004-08-23 | 2007-05-07 | Lilly Co Eli | Histamine h3 receptor agents, preparation and therapeutic uses. |
| WO2007062997A1 (en) * | 2005-11-30 | 2007-06-07 | F. Hoffmann-La Roche Ag | 1,1-dioxo-thiomorpholinyl indolyl methanone derivatives for use as h3 modulators |
| KR20090015098A (en) | 2006-05-30 | 2009-02-11 | 에프. 호프만-라 로슈 아게 | Piperidinyl pyrimidine derivatives |
| JP2010534217A (en) * | 2007-07-25 | 2010-11-04 | エフ．ホフマン−ラ ロシュ アーゲー | Benzofuran- and benzo [B] thiophene-2-carboxylic acid amide derivatives and their use as histamine 3 receptor modulators |
| US20090170869A1 (en) | 2007-09-06 | 2009-07-02 | Desmond John Best | Piperazine derivative having affinity for the histamine h3 receptor |
| WO2009100120A2 (en) | 2008-02-04 | 2009-08-13 | Neurogen Corporation | Pyridinyl-substituted piperazinyl oxoethyl tetrahydropyrazolopyridines |
| CA2719985A1 (en) | 2008-03-31 | 2009-10-08 | Evotec Ag | Tetrahydronaphthyridines and aza derivatives thereof as histamine h3 receptor antagonists |
| CN102015636B (en) | 2008-05-08 | 2014-08-13 | 埃沃特克股份有限公司 | Azetidines and cyclobutanes as histamine H3 receptor antagonists |
| CA2812970C (en) * | 2010-09-02 | 2015-01-13 | Suven Life Sciences Limited | Heterocyclyl compounds as histamine h3 receptor ligands |
-
2012
- 2012-12-05 KR KR1020157001952A patent/KR101707343B1/en active IP Right Grant
- 2012-12-05 ES ES12844650.7T patent/ES2592819T3/en active Active
- 2012-12-05 AP AP2014008139A patent/AP2014008139A0/en unknown
- 2012-12-05 WO PCT/IN2012/000796 patent/WO2014030170A1/en active Application Filing
- 2012-12-05 SI SI201230707A patent/SI2888243T1/en unknown
- 2012-12-05 JP JP2015528009A patent/JP5981654B2/en active Active
- 2012-12-05 US US14/419,474 patent/US9328092B2/en active Active
- 2012-12-05 MX MX2015000064A patent/MX360001B/en active IP Right Grant
- 2012-12-05 BR BR112015001524-7A patent/BR112015001524B1/en active IP Right Grant
- 2012-12-05 LT LTEP12844650.7T patent/LT2888243T/en unknown
- 2012-12-05 ME MEP-2016-190A patent/ME02519B/en unknown
- 2012-12-05 CA CA2878217A patent/CA2878217C/en active Active
- 2012-12-05 AU AU2012388383A patent/AU2012388383C1/en active Active
- 2012-12-05 HU HUE12844650A patent/HUE030901T2/en unknown
- 2012-12-05 EP EP12844650.7A patent/EP2888243B1/en active Active
- 2012-12-05 PL PL12844650T patent/PL2888243T3/en unknown
- 2012-12-05 EA EA201590413A patent/EA025136B1/en unknown
- 2012-12-05 CN CN201280075253.4A patent/CN104540812B/en active Active
- 2012-12-05 PT PT128446507T patent/PT2888243T/en unknown
- 2012-12-05 DK DK12844650.7T patent/DK2888243T3/en active
- 2012-12-05 RS RS20160783A patent/RS55158B1/en unknown
- 2012-12-05 SG SG11201408423XA patent/SG11201408423XA/en unknown
-
2014
- 2014-12-24 IL IL236437A patent/IL236437A/en active IP Right Grant
-
2015
- 2015-06-02 HK HK15105257.0A patent/HK1204620A1/en unknown
-
2016
- 2016-09-13 HR HRP20161167TT patent/HRP20161167T1/en unknown
- 2016-09-22 CY CY20161100943T patent/CY1118035T1/en unknown
- 2016-09-23 SM SM201600336T patent/SMT201600336B/en unknown
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