PL250072B1 - Fosfonowy analog argininy Cbz-Arg<sup>P</sup>(OPh)<sub>2</sub> do zastosowania jako środek przeciwbakteryjny - Google Patents

Fosfonowy analog argininy Cbz-Arg<sup>P</sup>(OPh)<sub>2</sub> do zastosowania jako środek przeciwbakteryjny

Info

Publication number
PL250072B1
PL250072B1 PL445140A PL44514023A PL250072B1 PL 250072 B1 PL250072 B1 PL 250072B1 PL 445140 A PL445140 A PL 445140A PL 44514023 A PL44514023 A PL 44514023A PL 250072 B1 PL250072 B1 PL 250072B1
Authority
PL
Poland
Prior art keywords
argp
oph
cbz
phosphonate
antibacterial agent
Prior art date
Application number
PL445140A
Other languages
English (en)
Other versions
PL445140A1 (pl
Inventor
Ewa Burchacka
Original Assignee
Politechnika Wrocławska
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Politechnika Wrocławska filed Critical Politechnika Wrocławska
Priority to PL445140A priority Critical patent/PL250072B1/pl
Publication of PL445140A1 publication Critical patent/PL445140A1/pl
Publication of PL250072B1 publication Critical patent/PL250072B1/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Emergency Medicine (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Przedmiotem wynalazku jest zastosowanie fosfonowego analogu argininy Cbz-ArgP(OPh)2 o wzorze 1 jako środka przeciwbakteryjnego do eliminowania bakterii wybranych z grupy: Finegoldia magna, Escherichia coli, Staphylococcus aureus, Serratia marcescens.
PL445140A 2023-06-06 2023-06-06 Fosfonowy analog argininy Cbz-Arg<sup>P</sup>(OPh)<sub>2</sub> do zastosowania jako środek przeciwbakteryjny PL250072B1 (pl)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL445140A PL250072B1 (pl) 2023-06-06 2023-06-06 Fosfonowy analog argininy Cbz-Arg<sup>P</sup>(OPh)<sub>2</sub> do zastosowania jako środek przeciwbakteryjny

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL445140A PL250072B1 (pl) 2023-06-06 2023-06-06 Fosfonowy analog argininy Cbz-Arg<sup>P</sup>(OPh)<sub>2</sub> do zastosowania jako środek przeciwbakteryjny

Publications (2)

Publication Number Publication Date
PL445140A1 PL445140A1 (pl) 2024-12-09
PL250072B1 true PL250072B1 (pl) 2026-08-10

Family

ID=93799879

Family Applications (1)

Application Number Title Priority Date Filing Date
PL445140A PL250072B1 (pl) 2023-06-06 2023-06-06 Fosfonowy analog argininy Cbz-Arg<sup>P</sup>(OPh)<sub>2</sub> do zastosowania jako środek przeciwbakteryjny

Country Status (1)

Country Link
PL (1) PL250072B1 (pl)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL236446B1 (pl) * 2017-12-14 2021-01-11 Politechnika Wroclawska Zastosowanie fosfonowych analogów lizyny oraz argininy w leczeniu chorób wywołanych przez wirusa Zika

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL236446B1 (pl) * 2017-12-14 2021-01-11 Politechnika Wroclawska Zastosowanie fosfonowych analogów lizyny oraz argininy w leczeniu chorób wywołanych przez wirusa Zika

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
BURCHACKA E. ET AL.,: "Biochimie, Volume 103, 08.2014., pp 137-143", SUBSTRATE PROFILING OF FINEGOLDIA MAGNA SUFA PROTEASE, INHIBITOR SCREENING AND APPLICATION TO PREVENT HUMAN FIBRINOGEN DEGRADATION AND BACTERIA GROWTH IN VITRO *
KOMAGAL KANNAN SIVARAMAN ET AL.,: "J. Med. Chem. 2013, 56, pp 5213−5217", SYNTHESIS AND STRUCTURE−ACTIVITY RELATIONSHIPS OF PHOSPHONIC ARGININE MIMETICS AS INHIBITORS OF THE M1 AND M17 AMINOPEPTIDASES FROM PLASMODIUM FALCIPARUM *

Also Published As

Publication number Publication date
PL445140A1 (pl) 2024-12-09