PL2376101T3 - Elektory beta-arestyny oraz ich kompozycje i sposoby stosowania - Google Patents

Elektory beta-arestyny oraz ich kompozycje i sposoby stosowania

Info

Publication number
PL2376101T3
PL2376101T3 PL09836520T PL09836520T PL2376101T3 PL 2376101 T3 PL2376101 T3 PL 2376101T3 PL 09836520 T PL09836520 T PL 09836520T PL 09836520 T PL09836520 T PL 09836520T PL 2376101 T3 PL2376101 T3 PL 2376101T3
Authority
PL
Poland
Prior art keywords
beta
compositions
methods
arrestin effectors
arrestin
Prior art date
Application number
PL09836520T
Other languages
English (en)
Inventor
Dennis Yamashita
Xiao-Tao Chen
Original Assignee
Trevena Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Trevena Inc filed Critical Trevena Inc
Publication of PL2376101T3 publication Critical patent/PL2376101T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/14Angiotensins: Related peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Virology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
PL09836520T 2008-12-29 2009-12-28 Elektory beta-arestyny oraz ich kompozycje i sposoby stosowania PL2376101T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14112608P 2008-12-29 2008-12-29
EP09836520.8A EP2376101B1 (en) 2008-12-29 2009-12-28 Beta-arrestin effectors and compositions and methods of use thereof
PCT/US2009/006719 WO2010077339A2 (en) 2008-12-29 2009-12-28 β-ARRESTIN EFFECTORS AND COMPOSITIONS AND METHODS OF USE THEREOF

Publications (1)

Publication Number Publication Date
PL2376101T3 true PL2376101T3 (pl) 2016-03-31

Family

ID=42310455

Family Applications (1)

Application Number Title Priority Date Filing Date
PL09836520T PL2376101T3 (pl) 2008-12-29 2009-12-28 Elektory beta-arestyny oraz ich kompozycje i sposoby stosowania

Country Status (16)

Country Link
US (7) US8486885B2 (pl)
EP (1) EP2376101B1 (pl)
JP (1) JP5647146B2 (pl)
CN (1) CN102333536B (pl)
AU (1) AU2009333883B2 (pl)
CA (1) CA2748340C (pl)
CY (1) CY1117184T1 (pl)
DK (1) DK2376101T3 (pl)
ES (1) ES2558629T3 (pl)
HR (1) HRP20151440T1 (pl)
HU (1) HUE026131T2 (pl)
NZ (1) NZ594302A (pl)
PL (1) PL2376101T3 (pl)
PT (1) PT2376101E (pl)
SI (1) SI2376101T1 (pl)
WO (1) WO2010077339A2 (pl)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE026131T2 (en) 2008-12-29 2016-05-30 Trevena Inc Beta-arresin effector and preparations and methods for their use
CN104168907A (zh) 2012-01-31 2014-11-26 特维娜有限公司 β-抑制蛋白效应器及其组合物与使用方法
CA2938986A1 (en) 2014-02-07 2015-08-13 Trevena, Inc. Crystalline and amorphous forms of a beta-arrestin effector
US9611293B2 (en) 2014-05-19 2017-04-04 Trevena, Inc. Synthesis of beta-arrestin effectors
CN104162146B (zh) * 2014-08-06 2016-12-07 中国人民解放军第二军医大学 β-抑制蛋白-1在制备预防或治疗心梗药物中的应用
WO2016196750A1 (en) * 2015-06-03 2016-12-08 Trevena, Inc. Beta-arrestin effectors and compositions and methods of use thereof
JOP20170133B1 (ar) * 2016-06-02 2022-03-15 Ferring Bv عوامل مضادة لمستقبل أنجيوتنسين-1
TWI776812B (zh) * 2016-06-02 2022-09-11 荷蘭商菲林公司 血管收縮素-1-受體拮抗劑
WO2018005591A1 (en) 2016-06-29 2018-01-04 Universite De Montreal Biarylmethyl heterocycles
WO2021216529A1 (en) * 2020-04-21 2021-10-28 Trevena, Inc. β-ARRESTIN EFFECTORS AND COMPOSITIONS AND METHODS OF USE THEREOF

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US3751404A (en) 1971-02-12 1973-08-07 Morton Norwich Products Inc L-prolyl-l-arginyl-l-volyl-l-tyrosyl-l-volyl-l-histidyl-l-prolyl-glycine
DE2360794C2 (de) 1973-12-06 1984-12-06 Hoechst Ag, 6230 Frankfurt Verfahren zur Herstellung von Peptiden
US3932624A (en) * 1974-06-17 1976-01-13 Morton-Norwich Products, Inc. Method for prolonging the inhibitory effect of saralasin on angiotensin II
JPS5825980B2 (ja) * 1976-02-12 1983-05-31 ヤマサ醤油株式会社 サイクリックヌクレオチドの定量法
US4298523A (en) 1980-06-17 1981-11-03 Ortho Pharmaceutical Corporation Methods and compositions for preparation of H-ARG-X-Z-Y-TYR-R
US4547489A (en) * 1984-06-11 1985-10-15 Ortho Pharmaceutical Corporation Conformationally restricted thymopentin-like compounds
US5182264A (en) * 1986-03-07 1993-01-26 Schering Corporation Angiotensin II receptor blockers as antiglaucoma agents
DE68903907T2 (de) 1988-09-05 1993-06-09 Sankyo Co Cyclisches peptid, seine herstellung und seine verwendung zur behandlung von cardiovasculaeren stoerungen.
GB8822483D0 (en) * 1988-09-24 1988-10-26 Medical Res Council Developments relating to mas oncogene
US5401629A (en) * 1990-08-07 1995-03-28 The Salk Institute Biotechnology/Industrial Associates, Inc. Assay methods and compositions useful for measuring the transduction of an intracellular signal
WO1992003145A1 (en) 1990-08-27 1992-03-05 Peptide Technology Ltd. Method of treating viral infection
AU1256692A (en) 1991-02-06 1992-09-07 Schering Corporation Combination of an angiotensin II antagonist or renin inhibitor with a neutral endopeptidase inhibitor
ES2168312T3 (es) 1993-09-24 2002-06-16 Univ Southern California Utilizacion de angiotensina iii y sus analogos para la reparacion tisular.
US5955430A (en) * 1993-09-24 1999-09-21 University Of Southern California Use of angiotensin II fragments and analogs thereof in tissue repair
ATE300287T1 (de) * 1994-02-08 2005-08-15 Novartis Pharma Gmbh Behandlung von normaldruckglaukom mit valsartan
US5958884A (en) * 1997-04-11 1999-09-28 The Brigham And Women's Hospital, Inc. Compositions and methods for treating erectile dysfunction
CA2315266C (en) 1997-12-12 2004-08-10 University Of Southern California Wound healing compositions
US20040214836A1 (en) * 1998-05-29 2004-10-28 Cheresh David A. Method of treatment of myocardial infarction
US6541669B1 (en) * 1998-06-08 2003-04-01 Theravance, Inc. β2-adrenergic receptor agonists
US20050202029A1 (en) * 2003-10-03 2005-09-15 The Board Of Trustees Of The Leland Stanford Junior University Family of cystatin-related chemoattractant proteins
US20070286863A1 (en) * 2006-05-17 2007-12-13 Christopher Sinal CMKLR regulation of adipogenesis and adipocyte metabolic function
WO2008130217A1 (en) * 2006-08-08 2008-10-30 Applied Nanosystems B.V. Cyclic angiotensin analogs
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CA2692372A1 (en) 2007-06-27 2008-12-31 Clayton Corporation Dispensing system and method of use
CA2723372A1 (en) 2008-05-05 2009-11-12 University Of Rochester Methods and compositions for the treatment or prevention of pathological cardiac remodeling and heart failure
US8038992B2 (en) * 2008-05-10 2011-10-18 The Board Of Trustees Of The Leland Stanford Junior University Target for regulating multiple sclerosis
WO2010019811A2 (en) * 2008-08-15 2010-02-18 The Board Of Trustees Of The Leland Stanford Junior University Methods for screening for modulators of ccrl2
HUE026131T2 (en) 2008-12-29 2016-05-30 Trevena Inc Beta-arresin effector and preparations and methods for their use
WO2011035332A1 (en) 2009-09-21 2011-03-24 Chemocentryx, Inc. Pyrrolidinone carboxamide derivatives as chemerin-r ( chemr23 ) modulators
US8450316B2 (en) 2010-06-24 2013-05-28 Trustees Of Tufts College Niacin mimetics, and methods of use thereof
WO2012150890A1 (en) 2011-05-02 2012-11-08 Lipidor Ab Antibacterial composition

Also Published As

Publication number Publication date
HRP20151440T1 (hr) 2016-01-29
CN102333536B (zh) 2014-08-13
ES2558629T3 (es) 2016-02-05
PT2376101E (pt) 2016-02-04
DK2376101T3 (en) 2016-01-18
NZ594302A (en) 2013-07-26
HUE026131T2 (en) 2016-05-30
EP2376101B1 (en) 2015-12-02
US20140336123A1 (en) 2014-11-13
US20140357562A1 (en) 2014-12-04
US8993511B2 (en) 2015-03-31
AU2009333883B2 (en) 2015-05-21
US8809260B2 (en) 2014-08-19
WO2010077339A3 (en) 2011-02-24
US20170298094A1 (en) 2017-10-19
US20140005114A1 (en) 2014-01-02
US20150166604A1 (en) 2015-06-18
JP2012514033A (ja) 2012-06-21
HK1162955A1 (zh) 2012-09-07
SI2376101T1 (sl) 2016-02-29
CY1117184T1 (el) 2017-04-05
EP2376101A4 (en) 2012-11-28
EP2376101A2 (en) 2011-10-19
JP5647146B2 (ja) 2014-12-24
US9534017B2 (en) 2017-01-03
US20100184701A1 (en) 2010-07-22
US8796204B2 (en) 2014-08-05
AU2009333883A1 (en) 2011-08-18
US20130274176A1 (en) 2013-10-17
CN102333536A (zh) 2012-01-25
US8486885B2 (en) 2013-07-16
CA2748340A1 (en) 2010-07-08
WO2010077339A2 (en) 2010-07-08
CA2748340C (en) 2017-01-24

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