PL2343052T3 - Hydrophilic filtration during manufacture of vaccine adjuvants - Google Patents

Hydrophilic filtration during manufacture of vaccine adjuvants

Info

Publication number
PL2343052T3
PL2343052T3 PL10252044T PL10252044T PL2343052T3 PL 2343052 T3 PL2343052 T3 PL 2343052T3 PL 10252044 T PL10252044 T PL 10252044T PL 10252044 T PL10252044 T PL 10252044T PL 2343052 T3 PL2343052 T3 PL 2343052T3
Authority
PL
Poland
Prior art keywords
during manufacture
vaccine adjuvants
filtration during
hydrophilic filtration
hydrophilic
Prior art date
Application number
PL10252044T
Other languages
Polish (pl)
Inventor
Gottfried Kraus
Robert Eskes
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43971135&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2343052(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PL2343052T3 publication Critical patent/PL2343052T3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B01F27/27—Mixers with stator-rotor systems, e.g. with intermeshing teeth or cylinders or having orifices
    • B01F27/271—Mixers with stator-rotor systems, e.g. with intermeshing teeth or cylinders or having orifices with means for moving the materials to be mixed radially between the surfaces of the rotor and the stator
    • B01F27/2711—Mixers with stator-rotor systems, e.g. with intermeshing teeth or cylinders or having orifices with means for moving the materials to be mixed radially between the surfaces of the rotor and the stator provided with intermeshing elements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/80—Mixing plants; Combinations of mixers
    • B01F33/81—Combinations of similar mixers, e.g. with rotary stirring devices in two or more receptacles
    • B01F33/811—Combinations of similar mixers, e.g. with rotary stirring devices in two or more receptacles in two or more consecutive, i.e. successive, mixing receptacles or being consecutively arranged
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
PL10252044T 2009-12-03 2010-12-03 Hydrophilic filtration during manufacture of vaccine adjuvants PL2343052T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28351709P 2009-12-03 2009-12-03
EP10252044.2A EP2343052B1 (en) 2009-12-03 2010-12-03 Hydrophilic filtration during manufacture of vaccine adjuvants

Publications (1)

Publication Number Publication Date
PL2343052T3 true PL2343052T3 (en) 2013-11-29

Family

ID=43971135

Family Applications (1)

Application Number Title Priority Date Filing Date
PL10252044T PL2343052T3 (en) 2009-12-03 2010-12-03 Hydrophilic filtration during manufacture of vaccine adjuvants

Country Status (22)

Country Link
US (3) US10213383B2 (en)
EP (3) EP2601933B1 (en)
JP (2) JP5754860B2 (en)
KR (2) KR101616735B1 (en)
CN (2) CN104688687A (en)
AU (1) AU2010325748B2 (en)
BR (1) BR112012013425A2 (en)
CA (1) CA2780425C (en)
CL (1) CL2012001268A1 (en)
DK (1) DK2343052T3 (en)
EA (1) EA025622B1 (en)
ES (3) ES2558056T3 (en)
HK (2) HK1159995A1 (en)
HR (1) HRP20130623T1 (en)
IL (1) IL219627B (en)
MX (1) MX2012005598A (en)
NZ (1) NZ599881A (en)
PL (1) PL2343052T3 (en)
PT (1) PT2343052E (en)
SG (1) SG10201501612RA (en)
SI (2) SI2601933T1 (en)
WO (1) WO2011067669A2 (en)

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DE102009056884B4 (en) 2009-12-03 2021-03-18 Novartis Ag Vaccine Adjuvants and Improved Methods for Making Same
MX2012005598A (en) 2009-12-03 2012-05-29 Novartis Ag Hydrophilic filtration during manufacture of vaccine adjuvants.
EP2506833B1 (en) † 2009-12-03 2014-04-16 Novartis AG Arranging interaction and back pressure chambers for microfluidization
PT3103784T (en) 2010-05-12 2019-05-20 Novartis Ag Manufacture of an oil-in-water emulsion comprising squalene
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RU2014140521A (en) 2012-03-08 2016-04-27 Новартис Аг ADJUVANT COMPOSITIONS OF BOOSTER VACCINES
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KR20170063750A (en) 2014-09-26 2017-06-08 세퀴러스 유케이 리미티드 Vaccination of immunocompromised subjects
EP3226904B1 (en) 2014-12-02 2019-03-06 Novartis AG Manufacture of surfactant-containing compositions
EP3393481A1 (en) * 2015-12-23 2018-10-31 Novartis Ag Oil-in-water emulsions including retinoic acid
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EP4171514A1 (en) * 2020-06-30 2023-05-03 Seqirus UK Limited Cold filtration of oil-in-water emulsion adjuvants
CN113876943A (en) * 2020-07-03 2022-01-04 神州细胞工程有限公司 Concentrated oil-in-water type submicron emulsion adjuvant and preparation method thereof

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Also Published As

Publication number Publication date
JP5754860B2 (en) 2015-07-29
IL219627B (en) 2018-05-31
JP2015098499A (en) 2015-05-28
US10213383B2 (en) 2019-02-26
EP2506832A2 (en) 2012-10-10
US20190201337A1 (en) 2019-07-04
KR101616735B1 (en) 2016-04-29
CA2780425A1 (en) 2011-06-09
ES2461852T3 (en) 2014-05-21
HK1175407A1 (en) 2013-07-05
CN102858322B (en) 2015-04-29
SG10201501612RA (en) 2015-04-29
KR101625623B1 (en) 2016-05-31
US20130129786A1 (en) 2013-05-23
PT2343052E (en) 2013-08-28
AU2010325748B2 (en) 2014-04-17
WO2011067669A3 (en) 2011-08-04
WO2011067669A2 (en) 2011-06-09
EP2506832B1 (en) 2014-02-26
SI2601933T1 (en) 2015-12-31
CL2012001268A1 (en) 2012-08-03
SI2506832T1 (en) 2014-06-30
NZ599881A (en) 2014-01-31
HK1159995A1 (en) 2012-08-10
HRP20130623T1 (en) 2013-09-30
EA025622B1 (en) 2017-01-30
JP2013512890A (en) 2013-04-18
EP2601933B1 (en) 2015-10-07
ES2558056T3 (en) 2016-02-01
EP2601933A1 (en) 2013-06-12
DK2343052T3 (en) 2013-09-02
BR112012013425A2 (en) 2020-11-03
KR20120101652A (en) 2012-09-14
US10799454B2 (en) 2020-10-13
EP2343052A1 (en) 2011-07-13
CA2780425C (en) 2014-02-04
AU2010325748A1 (en) 2012-05-31
EP2343052B1 (en) 2013-06-12
KR20150041812A (en) 2015-04-17
CN102858322A (en) 2013-01-02
MX2012005598A (en) 2012-05-29
ES2426969T3 (en) 2013-10-28
EA201270519A1 (en) 2012-12-28
US20210077395A1 (en) 2021-03-18
IL219627A0 (en) 2012-07-31
CN104688687A (en) 2015-06-10

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