PL2276740T3 - Ulepszony sposób wytwarzania pochodnych chinolino-3-karboksyamidowych - Google Patents
Ulepszony sposób wytwarzania pochodnych chinolino-3-karboksyamidowychInfo
- Publication number
- PL2276740T3 PL2276740T3 PL09738481T PL09738481T PL2276740T3 PL 2276740 T3 PL2276740 T3 PL 2276740T3 PL 09738481 T PL09738481 T PL 09738481T PL 09738481 T PL09738481 T PL 09738481T PL 2276740 T3 PL2276740 T3 PL 2276740T3
- Authority
- PL
- Poland
- Prior art keywords
- improved process
- carboxamide derivatives
- preparing quinoline
- quinoline
- preparing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4704—2-Quinolinones, e.g. carbostyril
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN1041CH2008 | 2008-04-28 | ||
EP20090738481 EP2276740B8 (en) | 2008-04-28 | 2009-04-27 | Improved process for preparing quinoline-3-carboxamide derivatives |
PCT/IB2009/005780 WO2009133468A1 (en) | 2008-04-28 | 2009-04-27 | Improved process for preparing quinoline-3-carboxamide derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
PL2276740T3 true PL2276740T3 (pl) | 2015-01-30 |
Family
ID=40974402
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL09738481T PL2276740T3 (pl) | 2008-04-28 | 2009-04-27 | Ulepszony sposób wytwarzania pochodnych chinolino-3-karboksyamidowych |
Country Status (4)
Country | Link |
---|---|
US (2) | US8552194B2 (pl) |
EP (1) | EP2276740B8 (pl) |
PL (1) | PL2276740T3 (pl) |
WO (1) | WO2009133468A1 (pl) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8552194B2 (en) * | 2008-04-28 | 2013-10-08 | Actavis Group Ptc Ehf | Process for preparing quinoline-3-carboxamide derivatives |
US20120009226A1 (en) * | 2008-12-17 | 2012-01-12 | Actavis Group Ptc Ehf | Highly pure laquinimod or a pharmaceutically acceptable salt thereof |
AU2011223692A1 (en) | 2010-03-03 | 2012-10-25 | Teva Pharmaceutical Industries Ltd. | Treatment of lupus nephritis using laquinimod |
BR112012033465A2 (pt) * | 2010-07-09 | 2017-06-20 | Active Biotech Ab | método para preparar um composto |
JP2013544819A (ja) * | 2010-11-28 | 2013-12-19 | マピ ファーマ リミテッド | ラキニモドナトリウムのようなキノリン誘導体の調製のための中間の化合物およびプロセス |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE52670B1 (en) * | 1981-03-03 | 1988-01-20 | Leo Ab | Heterocyclic carboxamides,compositions containing such compounds,and processes for their preparation |
US6077851A (en) * | 1998-04-27 | 2000-06-20 | Active Biotech Ab | Quinoline derivatives |
US6875869B2 (en) * | 2002-06-12 | 2005-04-05 | Active Biotech Ab | Process for the manufacture of quinoline derivatives |
US8552194B2 (en) * | 2008-04-28 | 2013-10-08 | Actavis Group Ptc Ehf | Process for preparing quinoline-3-carboxamide derivatives |
-
2009
- 2009-04-27 US US12/989,796 patent/US8552194B2/en not_active Expired - Fee Related
- 2009-04-27 PL PL09738481T patent/PL2276740T3/pl unknown
- 2009-04-27 WO PCT/IB2009/005780 patent/WO2009133468A1/en active Application Filing
- 2009-04-27 EP EP20090738481 patent/EP2276740B8/en not_active Not-in-force
-
2013
- 2013-09-09 US US14/020,941 patent/US9006443B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US8552194B2 (en) | 2013-10-08 |
WO2009133468A1 (en) | 2009-11-05 |
EP2276740B8 (en) | 2015-02-18 |
US20140005401A1 (en) | 2014-01-02 |
EP2276740A1 (en) | 2011-01-26 |
EP2276740B1 (en) | 2014-08-13 |
US20110105756A1 (en) | 2011-05-05 |
US9006443B2 (en) | 2015-04-14 |
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