PL21186B1 - A method of producing an anti-rheumatism medicament from bee venom. - Google Patents
A method of producing an anti-rheumatism medicament from bee venom. Download PDFInfo
- Publication number
- PL21186B1 PL21186B1 PL21186A PL2118634A PL21186B1 PL 21186 B1 PL21186 B1 PL 21186B1 PL 21186 A PL21186 A PL 21186A PL 2118634 A PL2118634 A PL 2118634A PL 21186 B1 PL21186 B1 PL 21186B1
- Authority
- PL
- Poland
- Prior art keywords
- bee venom
- producing
- bee
- skin
- venom
- Prior art date
Links
- 239000003659 bee venom Substances 0.000 title claims description 9
- 239000003814 drug Substances 0.000 title claims 2
- 239000002085 irritant Substances 0.000 claims description 4
- 231100000021 irritant Toxicity 0.000 claims description 4
- 239000000126 substance Substances 0.000 claims description 4
- 239000003925 fat Substances 0.000 claims description 3
- 239000011521 glass Substances 0.000 claims description 3
- 239000000843 powder Substances 0.000 claims description 3
- BPQQTUXANYXVAA-UHFFFAOYSA-N Orthosilicate Chemical compound [O-][Si]([O-])([O-])[O-] BPQQTUXANYXVAA-UHFFFAOYSA-N 0.000 claims description 2
- 239000013078 crystal Substances 0.000 claims description 2
- 239000000203 mixture Substances 0.000 claims description 2
- 229940079593 drug Drugs 0.000 claims 1
- ZOJBYZNEUISWFT-UHFFFAOYSA-N allyl isothiocyanate Chemical compound C=CCN=C=S ZOJBYZNEUISWFT-UHFFFAOYSA-N 0.000 description 3
- 239000008164 mustard oil Substances 0.000 description 3
- 206010020565 Hyperaemia Diseases 0.000 description 2
- 239000002561 chemical irritant Substances 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 239000002435 venom Substances 0.000 description 2
- 210000001048 venom Anatomy 0.000 description 2
- 231100000611 venom Toxicity 0.000 description 2
- 230000037374 absorbed through the skin Effects 0.000 description 1
- QKSKPIVNLNLAAV-UHFFFAOYSA-N bis(2-chloroethyl) sulfide Chemical compound ClCCSCCCl QKSKPIVNLNLAAV-UHFFFAOYSA-N 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 239000002973 irritant agent Substances 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 239000006199 nebulizer Substances 0.000 description 1
- 230000037368 penetrate the skin Effects 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
Description
Znane jest dzialanie lecznicze jadu pszczelnego przy reumatyzmie i podobnych schorzeniach, stosowanego podskórnie lub doskórnie.Stosowanie jadu pszczelnego w celach leczniczych droga wstrzykiwan jest bardzo bolesne i klopiotiliwe i z reguly moze byc wykonywane tylko przez lekarza. Wszelkie próby wprowadzenia jadu pszczelnego do organizmu w postaci skutecznej innym spo¬ sobem, nie daly dotad dobrych wyników.Mozna stosowac równiez jad pszczelny przez wprowadzanie go na powierzchnie skóry. W tym celu jad taki miesza sie z jed¬ nym lub kilkoma srodkami, drazniacemu skóre, np. olejkiem gorczycznym, zdolnym wywolac hyperemje, i mieszanine taka mie¬ sza z tluszczami zwierzecemi lub cialami podobneimit, które z latwoscia sa wchlania¬ ne przez skóre.Stosowanie tego rodzaju srodków po¬ siada jednak wady. Tak np. skóra pewnych osób jest (bardzo wrazliwa na dzialanie ta¬ kich chemicznych srodków drazniacych, jak olejek gorczyczny, siarczek dwuchloroety- Iowy i t. d. Poza tern takie srodki draznia¬ ce, jak olejek gorczyczny, posiadaja bardzo nieprzyjemny zapach, który uniemozliwia stosowanie go u niektórych osób.Obecnie stwierdzono, iz tego rodzaju drazniace srodki chemiczne mozna dosko¬ nale zastapic drazniacemi srodkami mecha- nicznemi. Nie chodzi tu bowiem o prawdzi¬ wa hyperemje, lecz o mikroskopijnie drób-ne uszkotk&sm -nagkótiko* daieki czemu o- siaga sie rezoribcje jadu pszczelnego jeszcze predzej, niz w razie zastosowania,draznia¬ cych srodków chemicznych. ..Jata mecha¬ niczne srodki drazniace mozna stosowac np, drobniutkie krysztalki krzemianu, pro¬ szek szklany, aillbo rozdrobnione zadla pszczól, które sa tansze od srodków che¬ micznych. Wspomniane mechaniczne srodki drazniace miesza sie z substancjami, latwo przenikajaicemi skóre, np. tluszczami zwie- rzecemi i p^dobnietW iniafer j^lami, i do ma¬ sy tej dodaje jadu pszczelnego. Do osia¬ gniecia zadanego skujtku^ (reeodatcji jadu) wystarczy juz uzycie* ojko^o 5%\ proszku i szklanego. Przy stosowaniu takiej miesza¬ niny mozna poslugiwac sie wcieraczka. PLThe healing effect of bee venom in rheumatism and similar diseases, applied subcutaneously or intradermally, is known. The use of bee venom for therapeutic purposes by injection is very painful and problematic and, as a rule, can only be performed by a doctor. Any attempt to introduce bee venom into the body in an effective form by other means has not been successful so far. It is also possible to use bee venom by introducing it onto the skin. For this purpose, the venom is mixed with one or more skin-irritating agents, such as mustard oil, capable of inducing hyperemia, and mixed with animal fats or imitation bodies which are easily absorbed through the skin. However, the use of such agents has disadvantages. For example, the skin of some people (very sensitive to chemical irritants such as mustard oil, dichloroethyl sulfide, etc.). Besides, irritants such as mustard oil have a very unpleasant odor that makes it impossible to use it. It has now been found that such chemical irritants can be perfectly replaced by irritating mechanical agents, for this is not a true hyperemia, but a microscopically small lesion and a smear nebulizer. resorption of bee venom even sooner than when irritating chemicals are used ... I can use mechanical irritants, for example, fine silicate crystals, glass powder, or fine bee blasts, which are cheaper than chemicals The aforementioned mechanical irritants are mixed with substances that easily penetrate the skin, such as animal fats and also he jams, and he adds bee venom to this mass. To achieve the desired effect (venom re-addition) it is enough to use 5% of the powder and glass. When using such a mixture, a wiper may be used. PL
Claims (1)
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL21186B1 true PL21186B1 (en) | 1935-04-30 |
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