PL2007B1

PL2007B1 - A method of producing highly active bacteria, yeasts or microbes.

Info

Publication number: PL2007B1
Application number: PL2007A
Authority: PL
Filing date: 1924-02-04
Publication date: 1925-05-30

Description

Wykryto, ze wlasnosc bakteryj, droz¬ dzy lub mikrobów niszczenia innych bak¬ teryj mozna tak silnie rozwinac i wyko¬ rzystac, przenoszac ich hodowle na inne kultury bakteryj, ze w ten sposób mozna otrzymywac nowe rodzaje lekarstw i szcze¬ pionek, znacznie przewyzszajace srodki stosowane w tym celu i znajdujace sie o- becnie w handlu.To wspólne rozwijanie sie bakteryj, po¬ siadajacych wlasnosc tepienia innych bak¬ teryj i trawienia bialka, albo bakteryj, prze¬ ciwdzialajacych fermentacji, z bakterjami zwalczanemi lub przesiedlanie hodowli pierwszych na podobne kultury zwalczane powieksza tak dalece wlasnosc niszczyciel¬ ska bakteryj i t. p., iz te ostatnie nabie¬ raja zdolnosci niszczenia zwalczanego cia¬ la w tak krótkim przeciagu czasu, ze sa¬ me nie zdazaja w okresie tym wywrzec dzialania szkodliwego.Jesli np. rozwijac i hodowac na kultu¬ rach tyfusowych np. Kazzilus subtilis, al¬ bo mesentericus, albo mycoides i prze¬ siedlac je systematycznie, co pewien! o- kres czasu, kilkakrotnie na nowe kultury tyfusowe, to otrzymujemy, po przeróbce sposobami zwyklem! lub znanemi, szcze¬ pionki, o dzialaniu znacznie przewyzsza- jacem znajdujace sie w handlu srodki, sto¬ sowane obecnie do celów profilaktyki i im- munizacji. To samo zachodzi np,, skoro bakterje, posiadajace wlasnosci niszcze¬ nia innych bakteryj, hodowac na gronkow-cach lub na bacylach tuberkulicznych i, przez systematyczne przenoszenie na in¬ ne kultury tuberkulicznej, skierow&c ich dzialanie przeciw tym tylko ostatnim. W ten sposób mozna wogóle otrzymywac le¬ karstwa i szczepionki o stopniu dzialania znacznie wyzszym od znanych obecnie.Szczepionki te i lekarstwa wykazuja ponadto te wyzszosc, iz mozna je jaknajdo- kladniej wypróbowac na zwierzetach, po^ dobnie, jak to czynimy £ surowicami sto- sowanemi w chorobach zakaznych.Sposób powyzszy mozna ponadto sto¬ sowac i do innych, niekoniecznie farma¬ ceutycznych celów, np. dla wytwarzania odpowiednich w sensie technicznym droz* dzy, co oznacza znaczny postep w sposo¬ bach pracy. PLIt has been found that the property of bacteria, yeast or microbes to destroy other bacteria can be so strongly developed and exploited by transferring their cultures to other cultures of bacteria that new types of drugs and vaccines can be obtained in this way, far exceeding the resources used for this purpose and presently commercially available. This is the joint development of bacteria that have the property of suppressing other bacteria and digesting protein, or bacteria that prevent fermentation, with the bacteria that are to be combated, or the resettlement of primary cultures to similar cultures the target increases the destructive properties of bacteria and so on that the latter acquire the ability to destroy the target body in such a short period of time that they themselves do not have a chance of causing a harmful effect during this period. typhus cultures, for example, Kazzilus subtilis, or mesentericus, or mycoides, and relocate them systematically, to be sure! the period of time, several times for new typhus cultures, we get it, after processing in the usual ways! or a known vaccine with an effect far exceeding that of the commercial agents currently used for prophylaxis and immunization. The same is true, for example, if bacteria having the property of destroying other bacteria are grown on staphylococci or tubercular bacilli and, by systematic transfer to other tubercular cultures, direct their action against only the latter. In this way it is possible to obtain medications and vaccines with a degree of action much higher than those known today. Moreover, these vaccines and drugs show the superiority that they can be tested in animals as well as we do with sera. The above method can also be used for other, not necessarily pharmaceutical, purposes, for example for the production of technically suitable yeast, which means a significant progress in working methods. PL

Claims

Patent claims. 1. A method of producing particularly active bacteria, various types of yeast or microbes, characterized by the fact that bacteria, yeasts or microbes having properties destroy others, digest the protein or counteract the fermentation caused by other bacteria, yeasts or microbes develop and resettles together on an appropriate nutrient with bacteria, yeasts or microbes, on which the given bacteria have a lethal effect.

2. A variant of the method according to claim 1 for the preparation of more active drugs and vaccines, characterized by the fact that bacteria, yeasts or microbes having other or similar properties, such as baszilus subtilis, mesentericus, mycoides, and so on are cultivated and develop on a suitable nutrient with the bacteria to be controlled by a vaccine or medicine, and the cultures thus obtained are processed as usual into vaccines and drugs. Kalle & Co. Aktienfesellschaf vol. Zastepca: M, Skrzypkowski, patent attorney. Print by L. Boguslawski, Warsaw. PL