PL1765298T3 - Method for producing a solid dosage form, which is safeguarded against abuse, while using a planetary gear extruder - Google Patents

Method for producing a solid dosage form, which is safeguarded against abuse, while using a planetary gear extruder

Info

Publication number
PL1765298T3
PL1765298T3 PL05757777T PL05757777T PL1765298T3 PL 1765298 T3 PL1765298 T3 PL 1765298T3 PL 05757777 T PL05757777 T PL 05757777T PL 05757777 T PL05757777 T PL 05757777T PL 1765298 T3 PL1765298 T3 PL 1765298T3
Authority
PL
Poland
Prior art keywords
producing
planetary gear
dosage form
solid dosage
safeguarded against
Prior art date
Application number
PL05757777T
Other languages
Polish (pl)
Inventor
Elisabeth Arkenau
Johannes Bartholomäus
Heinrich Kugelmann
Original Assignee
Gruenenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE102004032051A external-priority patent/DE102004032051A1/en
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Publication of PL1765298T3 publication Critical patent/PL1765298T3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
PL05757777T 2004-07-01 2005-06-29 Method for producing a solid dosage form, which is safeguarded against abuse, while using a planetary gear extruder PL1765298T3 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE102004032051A DE102004032051A1 (en) 2004-07-01 2004-07-01 Process for the preparation of a secured against misuse, solid dosage form
US10/890,704 US8114384B2 (en) 2004-07-01 2004-07-14 Process for the production of an abuse-proofed solid dosage form
PCT/EP2005/006983 WO2006002883A1 (en) 2004-07-01 2005-06-29 Method for producing a solid dosage form, which is safeguarded against abuse, while using a planetary gear extruder
EP05757777A EP1765298B1 (en) 2004-07-01 2005-06-29 Method for producing a solid dosage form, which is safeguarded against abuse, while using a planetary gear extruder

Publications (1)

Publication Number Publication Date
PL1765298T3 true PL1765298T3 (en) 2013-01-31

Family

ID=34972067

Family Applications (1)

Application Number Title Priority Date Filing Date
PL05757777T PL1765298T3 (en) 2004-07-01 2005-06-29 Method for producing a solid dosage form, which is safeguarded against abuse, while using a planetary gear extruder

Country Status (4)

Country Link
EP (1) EP1765298B1 (en)
AR (1) AR049839A1 (en)
PL (1) PL1765298T3 (en)
WO (1) WO2006002883A1 (en)

Families Citing this family (59)

* Cited by examiner, † Cited by third party
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EP1429739A1 (en) 2001-09-21 2004-06-23 Egalet A/S Polymer release system
WO2003024430A1 (en) 2001-09-21 2003-03-27 Egalet A/S Morphine polymer release system
US7776314B2 (en) 2002-06-17 2010-08-17 Grunenthal Gmbh Abuse-proofed dosage system
DE602004031096D1 (en) 2003-03-26 2011-03-03 Egalet As MORPHINE SYSTEM WITH CONTROLLED RELEASE
US20070048228A1 (en) 2003-08-06 2007-03-01 Elisabeth Arkenau-Maric Abuse-proofed dosage form
DE102004032051A1 (en) 2004-07-01 2006-01-19 Grünenthal GmbH Process for the preparation of a secured against misuse, solid dosage form
US8075872B2 (en) 2003-08-06 2011-12-13 Gruenenthal Gmbh Abuse-proofed dosage form
DE10336400A1 (en) 2003-08-06 2005-03-24 Grünenthal GmbH Anti-abuse dosage form
DE102005005446A1 (en) 2005-02-04 2006-08-10 Grünenthal GmbH Break-resistant dosage forms with sustained release
DE10361596A1 (en) 2003-12-24 2005-09-29 Grünenthal GmbH Process for producing an anti-abuse dosage form
DE102004032049A1 (en) 2004-07-01 2006-01-19 Grünenthal GmbH Anti-abuse, oral dosage form
DE102005005449A1 (en) 2005-02-04 2006-08-10 Grünenthal GmbH Process for producing an anti-abuse dosage form
SA07280459B1 (en) 2006-08-25 2011-07-20 بيورديو فارما إل. بي. Tamper Resistant Oral Pharmaceutical Dosage Forms Comprising an Opioid Analgesic
DE102007011485A1 (en) 2007-03-07 2008-09-11 Grünenthal GmbH Dosage form with more difficult abuse
AU2008258596B2 (en) 2007-06-04 2013-02-14 Egalet Ltd Controlled release pharmaceutical compositions for prolonged effect
BRPI0906467C1 (en) 2008-01-25 2021-05-25 Gruenenthal Gmbh pharmaceutical dosage form with modified tear-resistant outer shape and controlled release
LT2273983T (en) 2008-05-09 2016-10-25 Grünenthal GmbH Process for the preparation of an intermediate powder formulation and a final solid dosage form under usage of a spray congealing step
NZ594207A (en) 2009-02-06 2013-03-28 Egalet Ltd Immediate release composition resistant to abuse by intake of alcohol
AU2010265213B2 (en) 2009-06-24 2012-08-23 Egalet Ltd. Controlled release formulations
EP2456427B1 (en) 2009-07-22 2015-03-04 Grünenthal GmbH Hot-melt extruded controlled release dosage form
AU2010275754B2 (en) 2009-07-22 2014-05-15 Grünenthal GmbH Tamper-resistant dosage form for oxidation-sensitive opioids
WO2011095314A2 (en) 2010-02-03 2011-08-11 Grünenthal GmbH Preparation of a powdery pharmaceutical composition by means of an extruder
EP2366378A1 (en) 2010-03-01 2011-09-21 Dexcel Pharma Technologies Ltd. Sustained-release donepezil formulations
MX2013002293A (en) 2010-09-02 2013-05-09 Gruenenthal Gmbh Tamper resistant dosage form comprising an anionic polymer.
WO2012028319A1 (en) 2010-09-02 2012-03-08 Grünenthal GmbH Tamper resistant dosage form comprising inorganic salt
KR20130097201A (en) 2010-09-02 2013-09-02 그뤼넨탈 게엠베하 Tamper resistant dosage form comprising an anionic polymer
LT2736497T (en) 2011-07-29 2017-11-10 Grünenthal GmbH Tamper-resistant tablet providing immediate drug release
BR112014002022A2 (en) 2011-07-29 2017-02-21 Gruenenthal Gmbh tamper-resistant tablet providing immediate drug release
PE20141171A1 (en) 2011-10-06 2014-09-21 Gruenenthal Chemie ORAL PHARMACEUTICAL DOSAGE FORM RESISTANT TO ALTERATION INCLUDING OPIOID AGONIST AND OPIOID ANTAGONIST
EA201400590A1 (en) 2011-11-17 2014-11-28 Грюненталь Гмбх Resistance to fracture an oral pharmaceutical dosage form comprising a pharmacologically active ingredient opioid antagonist and / or a means, is disgusting, polyalkylene oxide and anionic polymers
EP2819657A1 (en) 2012-02-28 2015-01-07 Grünenthal GmbH Tamper-resistant pharmaceutical dosage form comprising nonionic surfactant
US20130225697A1 (en) 2012-02-28 2013-08-29 Grunenthal Gmbh Tamper-resistant dosage form comprising pharmacologically active compound and anionic polymer
AU2013248351B2 (en) 2012-04-18 2018-04-26 Grunenthal Gmbh Tamper resistant and dose-dumping resistant pharmaceutical dosage form
US10064945B2 (en) 2012-05-11 2018-09-04 Gruenenthal Gmbh Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc
ES2650945T3 (en) 2012-05-11 2018-01-23 Grünenthal GmbH Pharmaceutical resistant thermoformed pharmaceutical dosage form containing zinc
NZ704011A (en) 2012-07-06 2016-04-29 Egalet Ltd Abuse deterrent pharmaceutical compositions for controlled release
JP6466417B2 (en) 2013-05-29 2019-02-06 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング A tamper-resistant dosage form with a bimodal release profile
CA2907950A1 (en) 2013-05-29 2014-12-04 Grunenthal Gmbh Tamper-resistant dosage form containing one or more particles
EA032465B1 (en) 2013-07-12 2019-05-31 Грюненталь Гмбх Tamper-resistant oral pharmaceutical dosage form containing ethylene-vinyl acetate polymer and process for the production thereof
AU2014356581C1 (en) 2013-11-26 2020-05-28 Grunenthal Gmbh Preparation of a powdery pharmaceutical composition by means of cryo-milling
MX2016007848A (en) 2013-12-16 2016-09-07 Gruenenthal Gmbh Tamper resistant dosage form with bimodal release profile manufactured by co-extrusion.
CN106572980A (en) 2014-05-12 2017-04-19 格吕伦塔尔有限公司 Tamper resistant immediate release capsule formulation comprising tapentadol
CN106456550A (en) 2014-05-26 2017-02-22 格吕伦塔尔有限公司 Multiparticles safeguarded against ethanolic dose-dumping
EP3253376A1 (en) 2015-02-03 2017-12-13 Grünenthal GmbH Tamper-resistant dosage form comprising a polyethylene glycol graft copolymer
WO2016170094A1 (en) 2015-04-24 2016-10-27 Grünenthal GmbH Tamper-resistant fixed dose combination providing fast release of two drugs from particles
JP2018513864A (en) 2015-04-24 2018-05-31 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング Tamper resistant fixed dose combination resulting in rapid release of two drugs from particles and matrix
CA2983640A1 (en) 2015-04-24 2016-10-27 Grunenthal Gmbh Tamper-resistant fixed dose combination providing fast release of two drugs from different particles
AU2016251854A1 (en) 2015-04-24 2017-10-19 Grunenthal Gmbh Tamper-resistant dosage form with immediate release and resistance against solvent extraction
JP2018526414A (en) 2015-09-10 2018-09-13 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング Protection against oral overdose with abuse-inhibiting immediate release formulations
US20170296476A1 (en) 2016-04-15 2017-10-19 Grünenthal GmbH Modified release abuse deterrent dosage forms
CA3029869A1 (en) 2016-07-06 2018-01-11 Grunenthal Gmbh Reinforced pharmaceutical dosage form
CA3032598A1 (en) 2016-08-01 2018-02-08 Grunenthal Gmbh Tamper resistant dosage form comprising an anionic polysaccharide
AU2017310006A1 (en) 2016-08-12 2019-01-31 Grünenthal GmbH Tamper resistant formulation of ephedrine and its derivatives
CN111465390A (en) 2017-10-13 2020-07-28 格吕伦塔尔有限公司 Modified release abuse deterrent dosage forms
EP3473246A1 (en) 2017-10-19 2019-04-24 Capsugel Belgium NV Immediate release abuse deterrent formulations
TW202002957A (en) 2018-02-09 2020-01-16 德商歌林達有限公司 Tamper resistant formulation of ephedrine and its derivatives comprising a conversion inhibitor
EP3698776A1 (en) 2019-02-19 2020-08-26 Grünenthal GmbH Tamper-resistant dosage form with immediate release and resistance against solvent extraction
WO2021219576A1 (en) 2020-04-27 2021-11-04 Grünenthal GmbH Multiparticulate dosage form containing eva copolymer and additional excipient
WO2021219577A1 (en) 2020-04-27 2021-11-04 Grünenthal GmbH Dosage form comprising hot-melt extruded pellets containing eva copolymer and gliding agent

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001526229A (en) * 1997-12-22 2001-12-18 ユーロ−セルティーク，エス．エイ． How to prevent abuse of opioid dosage forms
DE19855440A1 (en) * 1998-12-01 2000-06-08 Basf Ag Process for the production of solid dosage forms by melt extrusion
DE19940944B4 (en) * 1999-08-31 2006-10-12 Grünenthal GmbH Retarded, oral, pharmaceutical dosage forms
US7144587B2 (en) * 2001-08-06 2006-12-05 Euro-Celtique S.A. Pharmaceutical formulation containing opioid agonist, opioid antagonist and bittering agent
DE10250084A1 (en) * 2002-10-25 2004-05-06 Grünenthal GmbH Dosage form protected against abuse

Also Published As

Publication number Publication date
AR049839A1 (en) 2006-09-06
EP1765298B1 (en) 2012-10-24
EP1765298A1 (en) 2007-03-28
WO2006002883A1 (en) 2006-01-12

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